PDB: 223790 resultsInfo pagesStatus searchChemie searchBIRD

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4DES	Crystal Structure of the Wild Type TTR Binding Chrysin (TTRwt:CHR) Descriptor: Transthyretin, chrysin Authors: Trivella, D.B.B, Polikarpov, I. Deposit date: 2012-01-21 Release date: 2012-11-21 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis. J.Struct.Biol., 180, 2012
2OCB	Crystal structure of human RAB9B in complex with a GTP analogue Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-9B, ... Authors: Hong, B, Shen, L, Walker, J.R, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) Deposit date: 2006-12-20 Release date: 2007-01-02 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of human RAB9B in complex with a GTP analogue To be Published
4HV1	Laser-induced microfragmentation of lysozyme crystals allows X-ray nanodiffraction characterization of individual domains (lb4) Descriptor: Lysozyme C Authors: Pechkova, E, Belmonte, L, Riekel, C, Popov, D, Koenig, C, Nicolini, C. Deposit date: 2012-11-05 Release date: 2013-11-20 Last modified: 2014-04-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Laser-induced microfragmentation of lysozyme crystals allows X-ray nanodiffraction characterization of individual domains To be Published
4HV2	Laser-induced microfragmentation of lysozyme crystals allows X-ray nanodiffraction characterization of individual domains (lb5) Descriptor: Lysozyme C Authors: Pechkova, E, Belmonte, L, Riekel, C, Popov, D, Koenig, C, Nicolini, C. Deposit date: 2012-11-05 Release date: 2013-11-20 Last modified: 2014-04-16 Method: X-RAY DIFFRACTION (2.501 Å) Cite: Laser-induced microfragmentation of lysozyme crystals allows X-ray nanodiffraction characterization of individual domains To be Published
3H12	Crystal structure of putative mandelate racemase from Bordetella Bronchiseptica RB50 Descriptor: SODIUM ION, mandelate racemase Authors: Malashkevich, V.N, Toro, R, Morano, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2009-04-10 Release date: 2009-04-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of putative mandelate racemase from Bordetella Bronchiseptica RB50 To be Published
4HVA	Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6 Descriptor: Caspase-6, N-[(2R)-1-(3-cyanophenyl)-3-hydroxypropan-2-yl]-5-(3,4-dimethoxyphenyl)furan-3-carboxamide, VEID Inhibitor Authors: Murray, J.M, Steffek, M. Deposit date: 2012-11-05 Release date: 2013-03-20 Method: X-RAY DIFFRACTION (2.074 Å) Cite: Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6. Plos One, 7, 2012
4HZ3	MthK pore crystallized in presence of TBSb Descriptor: Calcium-gated potassium channel mthK, HEXANE-1,6-DIOL, POTASSIUM ION Authors: Posson, D.J, McCoy, J.G, Nimigean, C.M. Deposit date: 2012-11-14 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The voltage-dependent gate in MthK potassium channels is located at the selectivity filter. Nat.Struct.Mol.Biol., 20, 2013
3H9S	The complex between TCR A6 and human Class I MHC HLA-A2 with the bound Tel1p peptide Descriptor: A6 TCR alpha chain, Beta-2-microglobulin, GLYCEROL, ... Authors: Borbulevych, O.Y, Baker, B.M. Deposit date: 2009-04-30 Release date: 2010-01-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility. Immunity, 31, 2009
4HXO	Brd4 Bromodomain 1 complex with 3-{[(3-METHYL-1,2-OXAZOL-5-YL)METHYL]SULFANYL}[1,2,4]TRIAZOLO[4,3-A]PYRIDINE inhibitor Descriptor: 3-{[(3-methyl-1,2-oxazol-5-yl)methyl]sulfanyl}[1,2,4]triazolo[4,3-a]pyridine, Bromodomain-containing protein 4 Authors: Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C. Deposit date: 2012-11-12 Release date: 2013-04-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain. J.Med.Chem., 56, 2013
4DQR	Ternary complex of Bacillus DNA Polymerase I Large Fragment E658A, DNA duplex, and rCTP (paired with dG of template) in presence of Mn2+ Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... Authors: Wang, W, Beese, L.S. Deposit date: 2012-02-16 Release date: 2012-06-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. J.Biol.Chem., 287, 2012
4DRQ	Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-1-((S)-1-(3,5-dichlorophenylsulfonyl)piperidine-2-carbonyloxy)-3-(3,4-dimethoxy -phenyl)propyl)phenoxy)acetic acid Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP5, {3-[(1S)-1-[({(2S)-1-[(3,5-dichlorophenyl)sulfonyl]piperidin-2-yl}carbonyl)oxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetic acid Authors: Gopalakrishnan, R, Kozany, C, Wang, Y, Hoogeland, B, Bracher, A, Hausch, F, Schneider, S. Deposit date: 2012-02-17 Release date: 2012-04-18 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1 Å) Cite: Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52. J.Med.Chem., 55, 2012
3T78	Crystal Structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in Complex with 5-Fluoroanthranilate Descriptor: 2-amino-5-fluorobenzoic acid, ACETATE ION, Indole-3-glycerol phosphate synthase, ... Authors: Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2011-07-29 Release date: 2012-08-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published
3T7K	Complex structure of Rtt107p and phosphorylated histone H2A Descriptor: Histone H2A.1, Regulator of Ty1 transposition protein 107 Authors: Li, X, Li, F, Wu, J, Shi, Y. Deposit date: 2011-07-30 Release date: 2012-02-15 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (2.028 Å) Cite: Structure of C-terminal Tandem BRCT Repeats of Rtt107 Protein Reveals Critical Role in Interaction with Phosphorylated Histone H2A during DNA Damage Repair J.Biol.Chem., 287, 2012
4DM1	Contribution of disulfide bond toward thermostability in hyperthermostable endocellulase Descriptor: 458aa long hypothetical endo-1,4-beta-glucanase, PHOSPHATE ION Authors: Kim, H.-W, Ishikawa, K. Deposit date: 2012-02-06 Release date: 2013-02-13 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Contribution of disulfide bond toward thermostability in hyperthermostable endocellulase To be Published
3GK0	Crystal structure of pyridoxal phosphate biosynthetic protein from Burkholderia pseudomallei Descriptor: 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, PHOSPHATE ION, Pyridoxine 5'-phosphate synthase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-03-09 Release date: 2009-03-17 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
3SPV	Crystal structure of a peptide-HLA complex Descriptor: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... Authors: Gras, S, Rossjohn, J. Deposit date: 2011-07-04 Release date: 2012-07-04 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Crystal structure of a peptide-HLA complex To be Published
3SRQ	S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines Descriptor: 1-[3-(2,4-diamino-6-methylquinazolin-7-yl)phenyl]ethanone, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Hilgers, M. Deposit date: 2011-07-07 Release date: 2011-08-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines. Bioorg.Med.Chem.Lett., 21, 2011
4HW5	Crystal Structure of the Human C3a anaphylatoxin Descriptor: Complement C3, SULFATE ION Authors: Bajic, G, Yatime, L, Andersen, G.R. Deposit date: 2012-11-07 Release date: 2012-12-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg. Protein Sci., 22, 2013
3GNN	Crystal structure of nicotinate-nucleotide pyrophosphorylase from Burkholderi pseudomallei Descriptor: Unknown Peptide, nicotinate-nucleotide diphosphorylase (carboxylating) Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-03-17 Release date: 2009-03-31 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Crystal structure of nicotinate-nucleotide pyrophosphorylase from Burkholderi pseudomallei To be Published
2OJK	Crystal Structure of Green Fluorescent Protein from Zoanthus sp at 2.2 A Resolution Descriptor: GFP-like fluorescent chromoprotein FP506 Authors: Pletneva, N.V, Pletnev, S.V, Tikhonova, T.V, Pletnev, V.Z. Deposit date: 2007-01-12 Release date: 2007-09-25 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Refined crystal structures of red and green fluorescent proteins from the button polyp Zoanthus. Acta Crystallogr.,Sect.D, 63, 2007
4HWT	Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor Descriptor: N-{[3-(2H-indazol-5-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, cytoplasmic, ... Authors: Hilgers, M.T. Deposit date: 2012-11-08 Release date: 2013-09-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J.Med.Chem., 56, 2013
3SSM	MycE Methyltransferase from the Mycinamycin Biosynthetic Pathway in Complex with Mg and SAH, Crystal form 1 Descriptor: MAGNESIUM ION, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE Authors: Akey, D.L, Smith, J.L. Deposit date: 2011-07-08 Release date: 2011-08-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.247 Å) Cite: A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway. J.Mol.Biol., 413, 2011
4I4W	Peptide length determines the outcome of T cell receptor/peptide-MHCI engagement Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... Authors: Rizkallah, P.J, Wooldridge, L, Cole, D.K. Deposit date: 2012-11-28 Release date: 2013-01-02 Last modified: 2015-11-25 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Peptide length determines the outcome of TCR/peptide-MHCI engagement. Blood, 121, 2013
4HXK	Brd4 Bromodomain 1 complex with 6,7-DIHYDROTHIENO[3,2-C]PYRIDIN-5(4H)-YL(1H-IMIDAZOL-1-YL)METHANONE inhibitor Descriptor: 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl(1H-imidazol-1-yl)methanone, Bromodomain-containing protein 4 Authors: Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C. Deposit date: 2012-11-12 Release date: 2013-04-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain. J.Med.Chem., 56, 2013
3GP0	Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Mitogen-activated protein kinase 11, ... Authors: Filippakopoulos, P, Barr, A, Fedorov, O, Keates, T, Soundararajan, M, Elkins, J, Salah, E, Burgess-Brown, N, Ugochukwu, E, Pike, A.C.W, Muniz, J, Roos, A, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2009-03-20 Release date: 2009-04-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib To be Published

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