3T78
Crystal Structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in Complex with 5-Fluoroanthranilate
Summary for 3T78
Entry DOI | 10.2210/pdb3t78/pdb |
Related | 3QJA 3T40 3T44 3T55 |
Descriptor | Indole-3-glycerol phosphate synthase, 2-amino-5-fluorobenzoic acid, MALONATE ION, ... (5 entities in total) |
Functional Keywords | indole-3-glycerol phosphate synthase (igps), tryptophan biosynthesis, structural genomics, tb structural genomics consortium, tbsgc, lyase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 28487.39 |
Authors | Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2011-07-29, release date: 2012-08-08, Last modification date: 2023-09-13) |
Primary citation | Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C. Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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