Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000162 | biological_process | L-tryptophan biosynthetic process |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004425 | molecular_function | indole-3-glycerol-phosphate synthase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006568 | biological_process | L-tryptophan metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0046391 | biological_process | 5-phosphoribose 1-diphosphate metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 5RG A 273 |
| Chain | Residue |
| A | LYS59 |
| A | MLI274 |
| A | ACT275 |
| A | SER62 |
| A | PRO63 |
| A | SER64 |
| A | PHE98 |
| A | PHE121 |
| A | ARG191 |
| A | LEU193 |
| A | LEU196 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MLI A 274 |
| Chain | Residue |
| A | LYS59 |
| A | ARG191 |
| A | GLU219 |
| A | SER220 |
| A | GLY242 |
| A | GLU243 |
| A | 5RG273 |
| A | HOH377 |
| A | HOH379 |
| A | HOH406 |
| A | HOH523 |
| A | HOH621 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 275 |
| Chain | Residue |
| A | PHE98 |
| A | LYS119 |
| A | PHE121 |
| A | 5RG273 |
| A | HOH491 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 276 |
| Chain | Residue |
| A | LYS31 |
| A | PRO74 |
| A | ASP103 |
| A | ASP104 |
| A | ARG157 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 277 |
| Chain | Residue |
| A | ARG200 |
| A | GLY221 |
| A | ARG223 |
| A | ASP227 |
| A | HOH510 |
Functional Information from PROSITE/UniProt
| site_id | PS00614 |
| Number of Residues | 18 |
| Details | IGPS Indole-3-glycerol phosphate synthase signature. VIaEVKRASPSagalat.I |
| Chain | Residue | Details |
| A | VAL54-ILE71 | |
