3T55
Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with Phenoxymethyl Benzoic Acid (PMBA)
Summary for 3T55
Entry DOI | 10.2210/pdb3t55/pdb |
Related | 3QJA 3T40 3T44 3T78 |
Descriptor | Indole-3-glycerol phosphate synthase, 3-(phenoxymethyl)benzoic acid, MALONATE ION, ... (5 entities in total) |
Functional Keywords | indole-3-glycerol phosphate synthase (igps), tryptophan biosynthesis, structural genomics, tb structural genomics consortium, tbsgc, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 28479.44 |
Authors | Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2011-07-26, release date: 2012-08-08, Last modification date: 2023-09-13) |
Primary citation | Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C. Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published, |
Experimental method |
Structure validation
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