Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

3T55

Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with Phenoxymethyl Benzoic Acid (PMBA)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000162biological_processL-tryptophan biosynthetic process
A0000287molecular_functionmagnesium ion binding
A0004425molecular_functionindole-3-glycerol-phosphate synthase activity
A0005886cellular_componentplasma membrane
A0006568biological_processL-tryptophan metabolic process
A0008652biological_processamino acid biosynthetic process
A0009073biological_processaromatic amino acid family biosynthetic process
A0009274cellular_componentpeptidoglycan-based cell wall
A0016829molecular_functionlyase activity
A0016831molecular_functioncarboxy-lyase activity
A0046391biological_process5-phosphoribose 1-diphosphate metabolic process
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE 4RG A 273
ChainResidue
ASER62
ALEU193
ALEU196
AHOH316
AHOH382
APRO63
ASER64
APHE98
ALYS119
AASP120
APHE121
ALEU140
AARG191

site_idAC2
Number of Residues10
DetailsBINDING SITE FOR RESIDUE MLI A 274
ChainResidue
ALYS59
AARG191
ASER220
ALEU240
AGLY242
AGLU243
AHOH289
AHOH307
AHOH314
AHOH426

site_idAC3
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 A 275
ChainResidue
ALEU27
ALYS31
AALA72
APRO74
AASP103
AARG157
AHOH299
AHOH303

Functional Information from PROSITE/UniProt
site_idPS00614
Number of Residues18
DetailsIGPS Indole-3-glycerol phosphate synthase signature. VIaEVKRASPSagalat.I
ChainResidueDetails
AVAL54-ILE71

246704

PDB entries from 2025-12-24

PDB statisticsPDBj update infoContact PDBjnumon