4HW5

Crystal Structure of the Human C3a anaphylatoxin

Summary for 4HW5

• Entry DOI: 10.2210/pdb4hw5/pdb
• Related: 4HWJ
• Descriptor: Complement C3, SULFATE ION (3 entities in total)
• Functional Keywords: complement system, anaphylatoxins, inflammation, innate immunity, four-helix-bundle, c5a, c5a desarg, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P01024
• Total number of polymer chains: 2
• Total formula weight: 19190.37

Authors

Bajic, G.,Yatime, L.,Andersen, G.R. (deposition date: 2012-11-07, release date: 2012-12-12, Last modification date: 2023-09-20)

• Primary citation: Bajic, G.,Yatime, L.,Klos, A.,Andersen, G.R.; Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg.; Protein Sci., 22:204-212, 2013; PubMed: 23184394; DOI: 10.1002/pro.2200

Experimental method

X-RAY DIFFRACTION (2.25 Å)