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7GSH
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BU of 7gsh by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000530a
Descriptor: 2-(4-methylphenyl)-N-{[(2S)-oxolan-2-yl]methyl}acetamide, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSG
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BU of 7gsg by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000316a
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1, methyl 4-sulfamoylbenzoate
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSJ
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BU of 7gsj by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000543a
Descriptor: (phenylmethyl) 4-oxidanylpiperidine-1-carboxylate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GSX
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BU of 7gsx by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMSOA001440b
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-methyl-1-benzofuran-2-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
7GT8
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BU of 7gt8 by Molmil
PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMSOA001439b
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-chloranylthiophene-2-sulfonamide, Tyrosine-protein phosphatase non-receptor type 1
Authors:Mehlman, T, Ginn, H.M, Keedy, D.A.
Deposit date:2024-01-03
Release date:2024-01-24
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data.
Biorxiv, 2024
2D0D
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BU of 2d0d by Molmil
Crystal Structure of a Meta-cleavage Product Hydrolase (CumD) A129V Mutant
Descriptor: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase, CHLORIDE ION, PHOSPHATE ION
Authors:Jun, S.Y, Fushinobu, S, Nojiri, H, Omori, T, Shoun, H, Wakagi, T.
Deposit date:2005-08-01
Release date:2006-06-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Improving the catalytic efficiency of a meta-cleavage product hydrolase (CumD) from Pseudomonas fluorescens IP01
Biochim.Biophys.Acta, 1764, 2006
7Z18
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BU of 7z18 by Molmil
E. coli C-P lyase bound to a PhnK ABC dimer and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, ...
Authors:Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
Deposit date:2022-02-24
Release date:2022-05-25
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (1.98 Å)
Cite:Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
2DD1
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BU of 2dd1 by Molmil
Three consecutive sheared GA pairs in 5'GGUGGAGGCU/3'PCCAAAGCCG
Descriptor: 5'-R(*GP*CP*CP*GP*AP*AP*AP*CP*CP*(P5P))-3', 5'-R(*GP*GP*UP*GP*GP*AP*GP*GP*CP*U)-3'
Authors:Chen, G, Kennedy, S.D, Krugh, T.R, Turner, D.H.
Deposit date:2006-01-19
Release date:2006-06-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA
Biochemistry, 45, 2006
7Z17
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BU of 7z17 by Molmil
E. coli C-P lyase bound to a PhnK ABC dimer in an open conformation
Descriptor: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ...
Authors:Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
Deposit date:2022-02-24
Release date:2022-05-25
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
7YWD
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BU of 7ywd by Molmil
Human GDAP1 core domain, trigonal crystal form
Descriptor: Ganglioside-induced differentiation-associated protein 1
Authors:Raasakka, A, Kursula, P.
Deposit date:2022-02-13
Release date:2022-06-08
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1.
Febs Open Bio, 12, 2022
7Z15
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BU of 7z15 by Molmil
E. coli C-P lyase bound to a PhnK/PhnL dual ABC dimer and ADP + Pi
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, ...
Authors:Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
Deposit date:2022-02-24
Release date:2022-06-22
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (1.93 Å)
Cite:Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
2DC5
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BU of 2dc5 by Molmil
Crystal structure of mouse glutathione S-transferase, mu7 (GSTM7) at 1.6 A resolution
Descriptor: Glutathione S-transferase, mu 7
Authors:Kamo, S, Kishishita, S, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-28
Release date:2006-06-28
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of mouse glutathione S-transferase, mu7 (GSTM7) at 1.6 A resolution
To be Published
2DD3
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BU of 2dd3 by Molmil
An alternating sheared AA pair in 5'GGUGAAGGCU/3'PCCGAAGCCG: II. The minor conformation with A6/A5/A16 stack
Descriptor: 5'-R(*GP*CP*CP*GP*AP*AP*GP*CP*CP*(P5P))-3', 5'-R(*GP*GP*UP*GP*AP*AP*GP*GP*CP*U)-3'
Authors:Chen, G, Kennedy, S.D, Krugh, T.R, Turner, D.H.
Deposit date:2006-01-19
Release date:2006-06-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA
Biochemistry, 45, 2006
2DD2
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BU of 2dd2 by Molmil
An alternating sheared AA pair in 5'GGUGAAGGCU/3'PCCGAAGCCG: I. The major conformation with A6/A15/A16 stack
Descriptor: 5'-R(*GP*CP*CP*GP*AP*AP*GP*CP*CP*(P5P))-3', 5'-R(*GP*GP*UP*GP*AP*AP*GP*GP*CP*U)-3'
Authors:Chen, G, Kennedy, S.D, Krugh, T.R, Turner, D.H.
Deposit date:2006-01-19
Release date:2006-06-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA
Biochemistry, 45, 2006
2TAA
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BU of 2taa by Molmil
STRUCTURE AND POSSIBLE CATALYTIC RESIDUES OF TAKA-AMYLASE A
Descriptor: CALCIUM ION, TAKA-AMYLASE A
Authors:Kusunoki, M, Matsuura, Y, Tanaka, N, Kakudo, M.
Deposit date:1982-10-18
Release date:1982-10-21
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure and possible catalytic residues of Taka-amylase A
J.Biochem.(Tokyo), 95, 1984
2DM6
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BU of 2dm6 by Molmil
Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex
Descriptor: INDOMETHACIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent leukotriene B4 12-hydroxydehydrogenase, ...
Authors:Hori, T, Ishijima, J, Yokomizo, T, Ago, H, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-20
Release date:2006-11-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of anti-configuration of indomethacin and leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complex reveals the structural basis of broad spectrum indomethacin efficacy
J.Biochem.(Tokyo), 140, 2006
2SIC
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BU of 2sic by Molmil
REFINED CRYSTAL STRUCTURE OF THE COMPLEX OF SUBTILISIN BPN' AND STREPTOMYCES SUBTILISIN INHIBITOR AT 1.8 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, STREPTOMYCES SUBTILISIN INHIBITOR (SSI), SUBTILISIN BPN'
Authors:Mitsui, Y, Takeuchi, Y, Hirono, S, Akagawa, H, Nakamura, K.T.
Deposit date:1991-04-01
Release date:1993-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined crystal structure of the complex of subtilisin BPN' and Streptomyces subtilisin inhibitor at 1.8 A resolution.
J.Mol.Biol., 221, 1991
2SNI
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BU of 2sni by Molmil
STRUCTURAL COMPARISON OF TWO SERINE PROTEINASE-PROTEIN INHIBITOR COMPLEXES. EGLIN-C-SUBTILISIN CARLSBERG AND CI-2-SUBTILISIN NOVO
Descriptor: CALCIUM ION, CHYMOTRYPSIN INHIBITOR 2, SUBTILISIN NOVO
Authors:Mcphalen, C.A, James, M.N.G.
Deposit date:1988-09-05
Release date:1988-09-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural comparison of two serine proteinase-protein inhibitor complexes: eglin-c-subtilisin Carlsberg and CI-2-subtilisin Novo.
Biochemistry, 27, 1988
2SBT
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BU of 2sbt by Molmil
A COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SUBTILISIN BPN AND SUBTILISIN NOVO
Descriptor: ACETONE, SUBTILISIN NOVO
Authors:Drenth, J, Hol, W.G.J, Jansonius, J.N, Koekoek, R.
Deposit date:1976-09-07
Release date:1976-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A comparison of the three-dimensional structures of subtilisin BPN' and subtilisin novo.
Cold Spring Harbor Symp.Quant.Biol., 36, 1972
2ST1
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BU of 2st1 by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF BACILLUS AMYLOLIQUEFACIENS SUBTILISIN AT 1.8 ANGSTROMS AND AN ANALYSIS OF THE STRUCTURAL CONSEQUENCES OF PEROXIDE INACTIVATION
Descriptor: CALCIUM ION, SUBTILISIN BPN', SULFATE ION
Authors:Bott, R.
Deposit date:1990-05-11
Release date:1991-07-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation.
J.Biol.Chem., 263, 1988
2UUY
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BU of 2uuy by Molmil
Structure of a tick tryptase inhibitor in complex with bovine trypsin
Descriptor: CALCIUM ION, CATIONIC TRYPSIN, CHLORIDE ION, ...
Authors:Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I.
Deposit date:2007-03-08
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
J.Mol.Biol., 368, 2007
2UZR
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BU of 2uzr by Molmil
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K)
Descriptor: RAC-alpha serine/threonine-protein kinase
Authors:Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E.
Deposit date:2007-05-01
Release date:2007-07-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
2ECR
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BU of 2ecr by Molmil
Crystal structure of the ligand-free form of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase
Descriptor: flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase
Authors:Kim, S.H, Hisano, T, Iwasaki, W, Ebihara, A, Miki, K.
Deposit date:2007-02-13
Release date:2008-01-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of the flavin reductase component (HpaC) of 4-hydroxyphenylacetate 3-monooxygenase from Thermus thermophilus HB8: Structural basis for the flavin affinity
Proteins, 70, 2008
8A4J
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BU of 8a4j by Molmil
Human GDAP1, A247V mutant
Descriptor: Ganglioside-induced differentiation-associated protein 1
Authors:Sutinen, A, Kursula, P.
Deposit date:2022-06-12
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability.
Plos One, 18, 2023
8A4K
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BU of 8a4k by Molmil
Human GDAP1, R282H mutant
Descriptor: Ganglioside-induced differentiation-associated protein 1
Authors:Sutinen, A, Kursula, P.
Deposit date:2022-06-12
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability.
Plos One, 18, 2023

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