8A4K

Human GDAP1, R282H mutant

Summary for 8A4K

Entry DOI	10.2210/pdb8a4k/pdb
Related	7B2G 8A4J
Descriptor	Ganglioside-induced differentiation-associated protein 1 (2 entities in total)
Functional Keywords	gst family, mitochondria, disease mutation, dimer, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	65510.78
Authors	Sutinen, A.,Kursula, P. (deposition date: 2022-06-12, release date: 2023-04-26, Last modification date: 2024-02-07)
Primary citation	Sutinen, A.,Paffenholz, D.,Nguyen, G.T.T.,Ruskamo, S.,Torda, A.E.,Kursula, P. Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability. Plos One, 18:e0284532-e0284532, 2023 Cited by PubMed: 37058526 DOI: 10.1371/journal.pone.0284532 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation