PDB: 8880 resultsInfo pagesStatus searchChemie searchBIRD

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4QPX	NV polymerase post-incorporation-like complex Descriptor: GLYCEROL, MANGANESE (II) ION, Polyprotein, ... Authors: Zamyatkin, D.F, Parra, F, Grochulski, P, Ng, K.K.S. Deposit date: 2014-06-25 Release date: 2015-04-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase. Acta Crystallogr.,Sect.D, 70, 2014
5C0W	Structure of a 12-subunit nuclear exosome complex bound to single-stranded RNA substrates Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Makino, D.L, Conti, E. Deposit date: 2015-06-12 Release date: 2015-07-29 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (4.6 Å) Cite: RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524, 2015
7AHO	RUVBL1-RUVBL2 heterohexameric ring after binding of RNA helicase DHX34 Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 Authors: Lopez-Perrote, A, Rodriguez, C.F, Llorca, O. Deposit date: 2020-09-25 Release date: 2020-11-25 Method: ELECTRON MICROSCOPY (4.18 Å) Cite: Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM. Elife, 9, 2020
5C0X	Structure of a 12-subunit nuclear exosome complex bound to structured RNA Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... Authors: Makino, D.L, Conti, E. Deposit date: 2015-06-12 Release date: 2015-08-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.812 Å) Cite: RNA degradation paths in a 12-subunit nuclear exosome complex. Nature, 524, 2015
7ENA	TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... Authors: Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. Deposit date: 2021-04-16 Release date: 2021-05-26 Last modified: 2021-06-16 Method: ELECTRON MICROSCOPY (4.07 Å) Cite: Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
7ENC	TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... Authors: Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y. Deposit date: 2021-04-16 Release date: 2021-05-26 Last modified: 2021-06-16 Method: ELECTRON MICROSCOPY (4.13 Å) Cite: Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
5MSG	Influenza B polymerase bound to vRNA promoter and capped RNA primer Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Cusack, S, Guilligay, D. Deposit date: 2017-01-04 Release date: 2017-02-08 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.8 Å) Cite: An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase. Nucleic Acids Res., 45, 2017
6SZU	Bat Influenza A polymerase pre-termination complex with pyrophosphate using 44-mer vRNA template with mutated oligo(U) sequence Descriptor: 5-oxidanyl-4-oxidanylidene-1-[(1-pyrrolo[2,3-b]pyridin-1-ylcyclopentyl)methyl]pyridine-3-carboxylic acid, MAGNESIUM ION, PYROPHOSPHATE 2-, ... Authors: Wandzik, J.M, Kouba, T, Cusack, S. Deposit date: 2019-10-02 Release date: 2020-04-15 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.41 Å) Cite: A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
6T0S	Bat Influenza A polymerase stuttering complex using 44-mer vRNA template with intact oligo(U) sequence Descriptor: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Wandzik, J.M, Kouba, T, Cusack, S. Deposit date: 2019-10-03 Release date: 2020-04-15 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.04 Å) Cite: A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
6TW1	Bat Influenza A polymerase termination complex with pyrophosphate using 44-mer vRNA template with mutated oligo(U) sequence Descriptor: 5-oxidanyl-4-oxidanylidene-1-[(1-pyrrolo[2,3-b]pyridin-1-ylcyclopentyl)methyl]pyridine-3-carboxylic acid, MAGNESIUM ION, PYROPHOSPHATE 2-, ... Authors: Wandzik, J.M, Kouba, T, Cusack, S. Deposit date: 2020-01-11 Release date: 2020-04-15 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 2020
6T2C	Bat Influenza A polymerase recycling complex Descriptor: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Wandzik, J.M, Kouba, T, Cusack, S. Deposit date: 2019-10-08 Release date: 2020-04-15 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.52 Å) Cite: A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
6T0N	Bat Influenza A polymerase pre-initiation complex Descriptor: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... Authors: Wandzik, J.M, Kouba, T, Cusack, S. Deposit date: 2019-10-03 Release date: 2020-04-15 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.54 Å) Cite: A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
8B3F	Pol II-CSB-CSA-DDB1-ELOF1 Descriptor: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... Authors: Kokic, G, Cramer, P. Deposit date: 2022-09-16 Release date: 2023-09-27 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Pol II-CSB-CSA-DDB1-ELOF1 structure. To Be Published
8B3D	Structure of the Pol II-TCR-ELOF1 complex. Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ... Authors: Kokic, G, Cramer, P. Deposit date: 2022-09-16 Release date: 2023-09-27 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structure of the Pol II-TCR-ELOF1 complex. To Be Published
6TU5	Influenza A/H7N9 polymerase core (apo) Descriptor: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Cusack, S, Pflug, A. Deposit date: 2020-01-02 Release date: 2020-04-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (3.325 Å) Cite: A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
7EDX	p53-bound TFIID-based core PIC on HDM2 promoter Descriptor: DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. Deposit date: 2021-03-17 Release date: 2021-05-05 Last modified: 2021-05-19 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EG7	TFIID-based core PIC on SCP promoter Descriptor: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. Deposit date: 2021-03-24 Release date: 2021-05-05 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EGA	TFIID-based intermediate PIC on PUMA promoter Descriptor: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. Deposit date: 2021-03-24 Release date: 2021-05-05 Last modified: 2021-05-19 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EG9	TFIID-based intermediate PIC on SCP promoter Descriptor: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y. Deposit date: 2021-03-24 Release date: 2021-05-05 Last modified: 2021-05-19 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EG8	TFIID-based core PIC on PUMA promoter Descriptor: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. Deposit date: 2021-03-24 Release date: 2021-05-05 Last modified: 2021-05-19 Method: ELECTRON MICROSCOPY (7.4 Å) Cite: Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
3O2Q	Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex Descriptor: PHOSPHATE ION, RNA polymerase II CTD Serine-5 phosphopeptide, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ... Authors: Tong, L, Xiang, K. Deposit date: 2010-07-22 Release date: 2010-10-06 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature, 467, 2010
1MWH	REOVIRUS POLYMERASE LAMBDA3 BOUND TO MRNA CAP ANALOG Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, MANGANESE (II) ION, MINOR CORE PROTEIN LAMBDA 3 Authors: Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. Deposit date: 2002-09-29 Release date: 2002-12-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: RNA Synthesis in a Cage-Structural Studies of Reovirus Polymerase lambda3 Cell(Cambridge,Mass.), 111, 2002
7BEF	Structures of class II bacterial transcription complexes Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Hao, M, Ye, F.Z, Zhang, X.D. Deposit date: 2020-12-23 Release date: 2021-12-01 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation. Adv Sci, 9, 2022
6GOV	Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX Descriptor: 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... Authors: Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. Deposit date: 2018-06-04 Release date: 2019-02-13 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor. Mol.Cell, 74, 2019
6RFG	Structure of the Vaccinia core protein E11 Descriptor: 15 kDa core protein Authors: Grimm, C, Fischer, U. Deposit date: 2019-04-15 Release date: 2019-12-11 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.897 Å) Cite: Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes. Cell, 179, 2019

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