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1KUT
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Structural Genomics, Protein TM1243, (SAICAR synthetase)
Descriptor: Phosphoribosylaminoimidazole-succinocarboxamide synthase
Authors:Zhang, R, Skarina, T, Beasley, S, Edwards, A, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2002-01-22
Release date:2002-08-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer.
Acta Crystallogr.,Sect.F, 62, 2006
3A4I
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BU of 3a4i by Molmil
Crystal structure of GMP synthetase PH1347 from Pyrococcus horikoshii OT3
Descriptor: GMP synthase [glutamine-hydrolyzing] subunit B
Authors:Maruoka, S, Horita, S, Lee, W.C, Nagata, K, Tanokura, M.
Deposit date:2009-07-07
Release date:2009-07-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase Subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3.
J.Mol.Biol., 395, 2010
7LLA
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BU of 7lla by Molmil
Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate (EM map was generated in Cryosparc with non-uniform refinement)
Descriptor: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-02-03
Release date:2021-03-03
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
7LJ9
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Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
Descriptor: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-01-28
Release date:2021-03-31
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
7LIW
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BU of 7liw by Molmil
Local refinement of human ATP citrate lyase E599Q mutant ASH domain
Descriptor: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
Authors:Wei, X, Marmorstein, R.
Deposit date:2021-01-28
Release date:2021-05-19
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
5IHP
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BU of 5ihp by Molmil
Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ADP and Magnesium
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cobyrinic Acid a,c-diamide synthase, MAGNESIUM ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-02-29
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ATP analog and Magnesium
TO BE PUBLISHED
3KJG
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ADP-bound state of CooC1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC
Authors:Jeoung, J.-H, Dobbek, H.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases
J.Mol.Biol., 396, 2010
6NOP
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Structure of Cyanothece McdA(D38A)-ATP complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cobyrinic acid ac-diamide synthase, MAGNESIUM ION
Authors:Schumacher, M.A.
Deposit date:2019-01-16
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs.
Nucleic Acids Res., 47, 2019
3KJH
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Zn-bound state of CooC1
Descriptor: CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC, ZINC ION
Authors:Jeoung, J.-H, Dobbek, H.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases
J.Mol.Biol., 396, 2010
3KJE
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BU of 3kje by Molmil
Empty state of CooC1
Descriptor: CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC
Authors:Jeoung, J.-H, Dobbek, H.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases
J.Mol.Biol., 396, 2010
3KJI
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BU of 3kji by Molmil
Zn and ADP bound state of CooC1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC, ...
Authors:Jeoung, J.-H, Dobbek, H.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases
J.Mol.Biol., 396, 2010
6Z2H
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BU of 6z2h by Molmil
Citryl-CoA lyase module of human ATP citrate lyase in complex with (3S)-citryl-CoA.
Descriptor: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ATP-citrate synthase, ...
Authors:Verschueren, K.H.G, Verstraete, K.
Deposit date:2020-05-15
Release date:2021-05-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
1M0T
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BU of 1m0t by Molmil
Yeast Glutathione Synthase
Descriptor: SULFATE ION, glutathione synthetase
Authors:Gogos, A, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2002-06-14
Release date:2002-12-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Large Conformational Changes in the Catalytic Cycle of Glutathione Synthase
Structure, 10, 2002
1PYX
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BU of 1pyx by Molmil
GSK-3 Beta complexed with AMP-PNP
Descriptor: Glycogen synthase kinase-3 beta, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
Deposit date:2003-07-09
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors
J.Mol.Biol., 333, 2003
1Q3D
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BU of 1q3d by Molmil
GSK-3 Beta complexed with Staurosporine
Descriptor: GLYCOGEN SYNTHASE KINASE-3 BETA, STAUROSPORINE
Authors:Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
Deposit date:2003-07-29
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003
1Q3W
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GSK-3 Beta complexed with Alsterpaullone
Descriptor: 9-NITRO-5,12-DIHYDRO-7H-BENZO[2,3]AZEPINO[4,5-B]INDOL-6-ONE, GLYCOGEN SYNTHASE KINASE-3 BETA
Authors:Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
Deposit date:2003-08-01
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003
1Q4L
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GSK-3 Beta complexed with Inhibitor I-5
Descriptor: 2-CHLORO-5-[4-(3-CHLORO-PHENYL)-2,5-DIOXO-2,5-DIHYDRO-1H-PYRROL-3-YLAMINO]-BENZOIC ACID, GLYCOGEN SYNTHASE KINASE-3 BETA
Authors:Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
Deposit date:2003-08-04
Release date:2003-10-14
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003
1EE1
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BU of 1ee1 by Molmil
CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD+ SYNTHETASE FROM BACILLUS SUBTILIS COMPLEXED WITH ONE MOLECULE ATP, TWO MOLECULES DEAMIDO-NAD+ AND ONE MG2+ ION
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NH(3)-DEPENDENT NAD(+) SYNTHETASE, ...
Authors:Devedjiev, Y, Symersky, J, Singh, R, Jedrzejas, M, Brouillette, C, Brouillette, W, Muccio, D, Chattopadhyay, D, Delucas, L.
Deposit date:2000-01-28
Release date:2001-06-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Stabilization of active-site loops in NH3-dependent NAD+ synthetase from Bacillus subtilis.
Acta Crystallogr.,Sect.D, 57, 2001
1Q41
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BU of 1q41 by Molmil
GSK-3 Beta complexed with Indirubin-3'-monoxime
Descriptor: (Z)-1H,1'H-[2,3']BIINDOLYLIDENE-3,2'-DIONE-3-OXIME, GLYCOGEN SYNTHASE KINASE-3 BETA
Authors:Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M.
Deposit date:2003-08-01
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003
2O5K
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BU of 2o5k by Molmil
Crystal Structure of GSK3beta in complex with a benzoimidazol inhibitor
Descriptor: 2-(2,4-DICHLORO-PHENYL)-7-HYDROXY-1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID [2-(4-METHANESULFONYLAMINO-PHENYL)-ETHYL]-AMIDE, Glycogen synthase kinase-3 beta
Authors:Shin, D, Lee, S.C, Heo, Y.S, Cho, Y.S, Kim, Y.E, Hyun, Y.L, Cho, J.M, Lee, Y.S, Ro, S.
Deposit date:2006-12-06
Release date:2007-10-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta
Bioorg.Med.Chem.Lett., 17, 2007
5SXO
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BU of 5sxo by Molmil
1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes
Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2
Authors:Soares da Costa, T.P, Nanson, J.D, Forwood, J.K.
Deposit date:2016-08-09
Release date:2016-11-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:1.35 angstrom resolution crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Listeria monocytogenes
To Be Published
7SBC
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BU of 7sbc by Molmil
Crystal structure of a GMP synthase from Acinetobacter baumannii AB5075-UW
Descriptor: CHLORIDE ION, GMP synthase [glutamine-hydrolyzing], MAGNESIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-09-24
Release date:2021-10-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of a GMP synthase from Acinetobacter baumannii AB5075-UW
To Be Published
4QAV
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BU of 4qav by Molmil
The structure of Beta-ketoacyl -(acyl carrier protein) synthase II (FabF) from Neisseria meningitidis
Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, FORMIC ACID, POTASSIUM ION
Authors:Nanson, J.D, Forwood, J.K.
Deposit date:2014-05-06
Release date:2014-06-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of Beta-ketoacyl -(acyl carrier protein) synthase II (FabF) from Neisseria meningitidis
to be published
2HRY
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BU of 2hry by Molmil
T. maritima PurL complexed with AMPPCP
Descriptor: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Ealick, S.E, Morar, M.
Deposit date:2006-07-20
Release date:2007-01-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily
Biochemistry, 45, 2006
2HS3
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BU of 2hs3 by Molmil
T. maritima PurL complexed with FGAR
Descriptor: N-(N-FORMYLGLYCYL)-5-O-PHOSPHONO-BETA-D-RIBOFURANOSYLAMINE, PHOSPHATE ION, Phosphoribosylformylglycinamidine synthase II
Authors:Ealick, S.E, Morar, M.
Deposit date:2006-07-21
Release date:2007-01-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily
Biochemistry, 45, 2006

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