8VHW
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![BU of 8vhw by Molmil](/molmil-images/mine/8vhw) | Neutron Structure of Peroxide-Soaked Trp161Phe MnSOD | Descriptor: | HYDROGEN PEROXIDE, MANGANESE (II) ION, Superoxide dismutase [Mn], ... | Authors: | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Coates, L, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | Deposit date: | 2024-01-02 | Release date: | 2024-07-31 | Method: | NEUTRON DIFFRACTION (2.3 Å) | Cite: | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition. Biorxiv, 2024
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8VHY
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![BU of 8vhy by Molmil](/molmil-images/mine/8vhy) | Neutron Structure of Reduced Trp161Phe MnSOD | Descriptor: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | Authors: | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Coates, L, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | Deposit date: | 2024-01-02 | Release date: | 2024-07-31 | Method: | NEUTRON DIFFRACTION (2.3 Å) | Cite: | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition. Biorxiv, 2024
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8XOK
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![BU of 8xok by Molmil](/molmil-images/mine/8xok) | Cryo-EM structure of human ABCC4 | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, PALMITIC ACID | Authors: | Zhang, P.F, Liu, Z. | Deposit date: | 2024-01-01 | Release date: | 2024-07-24 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 598, 2024
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8XOL
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![BU of 8xol by Molmil](/molmil-images/mine/8xol) | Cryo-EM structure of human ABCC4 with ANP bound in NBD1 | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | Authors: | Zhang, P.F, Liu, Z. | Deposit date: | 2024-01-01 | Release date: | 2024-07-17 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 598, 2024
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8XOM
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![BU of 8xom by Molmil](/molmil-images/mine/8xom) | Cryo-EM structure of human ABCC4 in complex with ANP-bound in NBD1 and METHOTREXATE | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | Authors: | Zhang, P.F, Liu, Z. | Deposit date: | 2024-01-01 | Release date: | 2024-07-17 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 598, 2024
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8XOJ
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![BU of 8xoj by Molmil](/molmil-images/mine/8xoj) | Cryo-EM structure of GPR30-Gq complex structure in the presence of G-1 | Descriptor: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOH
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![BU of 8xoh by Molmil](/molmil-images/mine/8xoh) | Cryo-EM structure of GPR30-Gq complex structure in the presence of E2 | Descriptor: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOG
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![BU of 8xog by Molmil](/molmil-images/mine/8xog) | Cryo-EM structure of apo-GPR30-Gq complex structure | Descriptor: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOF
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![BU of 8xof by Molmil](/molmil-images/mine/8xof) | Cryo-EM structure of Lys05 bound GPR30-Gq complex structure | Descriptor: | G protein subunit q, G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8XOI
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![BU of 8xoi by Molmil](/molmil-images/mine/8xoi) | Cryo-EM structure of GPR30-Gq complex structure in the presence of fulvestrant | Descriptor: | G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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8RKS
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![BU of 8rks by Molmil](/molmil-images/mine/8rks) | Structure of VPS29-VPS35 bound to the LFa motif R21 of Fam21. | Descriptor: | Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35, WASH complex subunit 2A | Authors: | Romano-Moreno, M, Astorga-Simon, E.N, Rojas, A.L, Hierro, A. | Deposit date: | 2023-12-30 | Release date: | 2024-04-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29, and FAM21. Protein Sci., 33, 2024
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8VGZ
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![BU of 8vgz by Molmil](/molmil-images/mine/8vgz) | |
8RKU
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![BU of 8rku by Molmil](/molmil-images/mine/8rku) | Conformational Landscape of the Type V-K CRISPR-associated TransposonIntegration Assembly CAST V-K TnsC domain local-refinement map | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Non-target strand - LE, ... | Authors: | Tenjo-Castano, F, Mesa, P, Montoya, G. | Deposit date: | 2023-12-30 | Release date: | 2024-06-19 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Conformational landscape of the type V-K CRISPR-associated transposon integration assembly. Mol.Cell, 84, 2024
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8RKV
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![BU of 8rkv by Molmil](/molmil-images/mine/8rkv) | Conformational Landscape of the Type V-K CRISPR-associated TransposonIntegration Assembly CAST V-K TnsB domain local-refinement map | Descriptor: | LE, MAGNESIUM ION, Non-target strand - LE, ... | Authors: | Tenjo-Castano, F, Mesa, P, Montoya, G. | Deposit date: | 2023-12-30 | Release date: | 2024-06-19 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Conformational landscape of the type V-K CRISPR-associated transposon integration assembly. Mol.Cell, 84, 2024
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8RKT
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![BU of 8rkt by Molmil](/molmil-images/mine/8rkt) | Conformational Landscape of the Type V-K CRISPR-associated TransposonIntegration Assembly CAST V-K Cas12k domain local-refinement map | Descriptor: | MAGNESIUM ION, Non-target strand - LE, ShCas12k, ... | Authors: | Tenjo-Castano, F, Mesa, P, Montoya, G. | Deposit date: | 2023-12-30 | Release date: | 2024-06-19 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.35 Å) | Cite: | Conformational landscape of the type V-K CRISPR-associated transposon integration assembly. Mol.Cell, 84, 2024
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8XN6
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![BU of 8xn6 by Molmil](/molmil-images/mine/8xn6) | The Crystal Structure of GSK3b from Biortus. | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glycogen synthase kinase-3 beta, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. | Deposit date: | 2023-12-29 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Crystal Structure of GSK3b from Biortus. To Be Published
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8RKR
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![BU of 8rkr by Molmil](/molmil-images/mine/8rkr) | Structure of human DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (ALDH4A1) complexed with a monophosphate-tweezer | Descriptor: | (1R,5S,9S,16R,20R,24S,28S,35R)-22-(Dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaen-3-ol, BENZOIC ACID, Delta-1-pyrroline-5-carboxylate dehydrogenase, ... | Authors: | Porfetye, A.T, Vetter, I.R. | Deposit date: | 2023-12-28 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | How Do Molecular Tweezers Bind to Proteins? Lessons from X-ray Crystallography. Molecules, 29, 2024
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8RKQ
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![BU of 8rkq by Molmil](/molmil-images/mine/8rkq) | Structure of human DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (ALDH4A1) complexed with the molecular tweezer CLR01 | Descriptor: | (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | Authors: | Porfetye, A.T, Vetter, I.R. | Deposit date: | 2023-12-28 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | How Do Molecular Tweezers Bind to Proteins? Lessons from X-ray Crystallography. Molecules, 29, 2024
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8XMS
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![BU of 8xms by Molmil](/molmil-images/mine/8xms) | |
8XMD
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![BU of 8xmd by Molmil](/molmil-images/mine/8xmd) | Pre-translocated Pol IV transcription elongation complex | Descriptor: | DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... | Authors: | Huang, K, Fang, C.L, Zhang, Y. | Deposit date: | 2023-12-27 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
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8XME
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![BU of 8xme by Molmil](/molmil-images/mine/8xme) | Backtracked Pol IV transcription elongation complex | Descriptor: | DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... | Authors: | Huang, K, Fang, C.L, Zhang, Y. | Deposit date: | 2023-12-27 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
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8XMB
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![BU of 8xmb by Molmil](/molmil-images/mine/8xmb) | NTP-bound Pol IV transcription elongation complex | Descriptor: | DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... | Authors: | Huang, K, Fang, C.L, Zhang, Y. | Deposit date: | 2023-12-27 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
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8XMC
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![BU of 8xmc by Molmil](/molmil-images/mine/8xmc) | |
8VGC
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![BU of 8vgc by Molmil](/molmil-images/mine/8vgc) | Complex of ExbD with D-box peptide: Orthorhombic form | Descriptor: | Biopolymer transport protein ExbD, GLN-PRO-ILE-SER-VAL-THR-MET-VAL-THR-PRO | Authors: | Loll, P.J. | Deposit date: | 2023-12-27 | Release date: | 2024-02-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Discovery and structural characterization of the D-box, a conserved TonB motif that couples an inner-membrane motor to outer-membrane transport. J.Biol.Chem., 300, 2024
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8VGD
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![BU of 8vgd by Molmil](/molmil-images/mine/8vgd) | Complex of ExbD with D-box peptide: Tetragonal form | Descriptor: | Biopolymer transport protein ExbD, GLN-PRO-ILE-SER-VAL-THR-MET-VAL-THR | Authors: | Loll, P.J. | Deposit date: | 2023-12-27 | Release date: | 2024-02-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Discovery and structural characterization of the D-box, a conserved TonB motif that couples an inner-membrane motor to outer-membrane transport. J.Biol.Chem., 300, 2024
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