8HRD
| Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant in complex with IMCAS74 Fab and W14 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS74 Fab heavy chain, IMCAS74 Fab light chain, ... | Authors: | Zhao, R.C, Wu, L.L, Han, P. | Deposit date: | 2022-12-15 | Release date: | 2023-12-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Defining a de novo non-RBM antibody as RBD-8 and its synergistic rescue of immune-evaded antibodies to neutralize Omicron SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
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8V0T
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8V0M
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8V0X
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8U28
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8UUL
| Prototypic SARS-CoV-2 spike (containing K417) in the closed conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Geng, Q, Liu, B, Li, F. | Deposit date: | 2023-11-01 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein. Elife, 12, 2023
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8UUM
| Prototypic SARS-CoV-2 spike (containing K417) in the open conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose, ... | Authors: | Geng, Q, Liu, B, Li, F. | Deposit date: | 2023-11-01 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein. Elife, 12, 2023
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8UUN
| Prototypic SARS-CoV-2 spike (containing V417) in the closed conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Geng, Q, Liu, B, Li, F. | Deposit date: | 2023-11-01 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein. Elife, 12, 2023
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8UUO
| Prototypic SARS-CoV-2 spike (containing V417) in the open conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, alpha-D-mannopyranose, ... | Authors: | Geng, Q, Liu, B, Li, F. | Deposit date: | 2023-11-01 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein. Elife, 12, 2023
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8U1G
| Prefusion-stabilized SARS-CoV-2 S2 subunit | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2 | Authors: | Hsieh, C.-L, McLellan, J.S. | Deposit date: | 2023-08-31 | Release date: | 2024-01-24 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge. Nat Commun, 15, 2024
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8UKF
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8UKD
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8WLR
| Cryo-EM structure of SARS-CoV-2 prototype spike protein receptor-binding domain in complex with hippopotamus ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike glycoprotein, ... | Authors: | Han, P, Yang, R.R, Li, S.H. | Deposit date: | 2023-09-30 | Release date: | 2024-03-27 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Molecular basis of hippopotamus ACE2 binding to SARS-CoV-2. J.Virol., 98, 2024
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8WLO
| Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with hippopotamus ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ... | Authors: | Han, P, Yang, R.R, Li, S.H. | Deposit date: | 2023-09-30 | Release date: | 2024-03-27 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Molecular basis of hippopotamus ACE2 binding to SARS-CoV-2. J.Virol., 98, 2024
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8VYF
| SARS-CoV-2 S NTD (C.37 Lambda variant) plus S2L20 and S2X303 Fabs, local refinement | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Heavy Chain, ... | Authors: | McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2024-02-08 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features. Nat Commun, 15, 2024
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8VYG
| SARS-CoV-2 S RBD (C.37 Lambda variant) plus S309 Fab, local refinement | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Heavy Chain, S309 Light Chain, ... | Authors: | McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2024-02-08 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features. Nat Commun, 15, 2024
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8WMF
| Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein (closed-1 state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. | Deposit date: | 2023-10-03 | Release date: | 2024-04-24 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant. Microbiol Immunol, 2024
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8WMD
| Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein (closed-2 state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. | Deposit date: | 2023-10-03 | Release date: | 2024-04-24 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant. Microbiol Immunol, 2024
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8WHV
| Spike Trimer of BA.2.86 with three RBDs down | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yue, C, Liu, P. | Deposit date: | 2023-09-23 | Release date: | 2024-07-03 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8WHW
| Spike Trimer of BA.2.86 with single RBD up | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Yue, C, Liu, P. | Deposit date: | 2023-09-23 | Release date: | 2024-07-03 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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8VAO
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8W4F
| SARS-CoV-2 spike protein in complex with a trivalent nanobody | Descriptor: | Spike glycoprotein, Tribody | Authors: | Jiang, X.Y, Qian, J.Q, Zhu, H.X, Qin, Q, Huang, Q. | Deposit date: | 2023-08-24 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure-guided design of a trivalent nanobody cluster targeting SARS-CoV-2 spike protein. Int.J.Biol.Macromol., 256, 2024
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8VQ9
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8VQB
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8VQA
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