8UUO

Prototypic SARS-CoV-2 spike (containing V417) in the open conformation

Summary for 8UUO

• Entry DOI: 10.2210/pdb8uuo/pdb
• EMDB information: 42589 42590 42591 42592
• Descriptor: Spike glycoprotein, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: prototypic sars-cov-2 spike v417, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 3
• Total formula weight: 406980.53

Authors

Geng, Q.,Liu, B.,Li, F. (deposition date: 2023-11-01, release date: 2023-11-29)

• Primary citation: Geng, Q.,Wan, Y.,Hsueh, F.C.,Shang, J.,Ye, G.,Bu, F.,Herbst, M.,Wilkens, R.,Liu, B.,Li, F.; Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein.; Elife, 12:-, 2023; PubMed: 37991488; DOI: 10.7554/eLife.74060

Experimental method

ELECTRON MICROSCOPY (3.9 Å)