8XOW
| Mature virion portal of bacteriophage lambda | Descriptor: | Head completion protein, Head-tail connector protein FII, Portal protein B, ... | Authors: | Wang, J.W, Gu, Z.W. | Deposit date: | 2024-01-02 | Release date: | 2024-04-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Structural morphing in the viral portal vertex of bacteriophage lambda. J.Virol., 98, 2024
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8XOU
| Prohead portal vertex of bacteriophage lambda | Descriptor: | Major capsid protein, Portal protein B | Authors: | Wang, J.W, Gu, Z.W. | Deposit date: | 2024-01-02 | Release date: | 2024-04-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (5.58 Å) | Cite: | Structural morphing in the viral portal vertex of bacteriophage lambda. J.Virol., 98, 2024
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8XOT
| Prohead portal of bacteriophage lambda | Descriptor: | Portal protein B | Authors: | Wang, J.W, Gu, Z.W. | Deposit date: | 2024-01-02 | Release date: | 2024-04-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural morphing in the viral portal vertex of bacteriophage lambda. J.Virol., 98, 2024
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8XOM
| Cryo-EM structure of human ABCC4 in complex with ANP-bound in NBD1 and METHOTREXATE | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | Authors: | Zhang, P.F, Liu, Z. | Deposit date: | 2024-01-01 | Release date: | 2024-07-17 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 598, 2024
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8XOL
| Cryo-EM structure of human ABCC4 with ANP bound in NBD1 | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ... | Authors: | Zhang, P.F, Liu, Z. | Deposit date: | 2024-01-01 | Release date: | 2024-07-17 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 598, 2024
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8XOK
| Cryo-EM structure of human ABCC4 | Descriptor: | 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, PALMITIC ACID | Authors: | Zhang, P.F, Liu, Z. | Deposit date: | 2024-01-01 | Release date: | 2024-07-24 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport. Febs Lett., 598, 2024
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8XNG
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8XN8
| The Crystal Structure of SRC from Biortus. | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. | Deposit date: | 2023-12-29 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Crystal Structure of SRC from Biortus. To Be Published
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8XN7
| Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with compound 9f | Descriptor: | 5-amino-2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-8-(2-(trifluoromethyl)benzyl)pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase kinase kinase kinase 1 | Authors: | Huang, W.X, Liu, R, Ding, K. | Deposit date: | 2023-12-29 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors. Eur.J.Med.Chem., 269, 2024
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8XN6
| The Crystal Structure of GSK3b from Biortus. | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glycogen synthase kinase-3 beta, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Qi, J, Wu, B. | Deposit date: | 2023-12-29 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Crystal Structure of GSK3b from Biortus. To Be Published
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8XMO
| Voltage-gated sodium channel Nav1.7 variant M4 | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, N, Li, Z, Wu, Q, Huang, G. | Deposit date: | 2023-12-27 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Dissection of the structure-function relationship of Na v channels. Proc.Natl.Acad.Sci.USA, 121, 2024
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8XMN
| Voltage-gated sodium channel Nav1.7 variant M2 | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yan, N, Li, Z, Wu, Q, Huang, G. | Deposit date: | 2023-12-27 | Release date: | 2024-03-06 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Dissection of the structure-function relationship of Na v channels. Proc.Natl.Acad.Sci.USA, 121, 2024
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8XMM
| Voltage-gated sodium channel Nav1.7 variant M9 | Descriptor: | (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | Authors: | Yan, N, Li, Z, Wu, Q, Huang, G. | Deposit date: | 2023-12-27 | Release date: | 2024-03-06 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Dissection of the structure-function relationship of Na v channels. Proc.Natl.Acad.Sci.USA, 121, 2024
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8XM7
| Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex: RhoG/DOCK5/ELMO1 focused map | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2023-12-27 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.91 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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8XM1
| Phytase mutant APPAmut4 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Phytase | Authors: | Tu, T, Wang, Q. | Deposit date: | 2023-12-27 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The mutant crystal structure of phytase APPAmut4 from Yersinia intermedia To Be Published
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8XLQ
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8XLO
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8XLN
| Structure of the SARS-CoV-2 EG.5.1 spike RBD in complex with ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. | Deposit date: | 2023-12-26 | Release date: | 2024-05-01 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant. Microbiol Immunol, 68, 2024
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8XLM
| Structure of the SARS-CoV-2 EG.5.1 spike glycoprotein in complex with ACE2 (1-up state) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Nomai, T, Anraku, Y, Kita, S, Hashiguchi, T, Maenaka, K. | Deposit date: | 2023-12-26 | Release date: | 2024-05-01 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant. Microbiol Immunol, 68, 2024
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8XLD
| Structure of the GFP:GFP-nanobody complex from Biortus. | Descriptor: | 1,2-ETHANEDIOL, Nanobody(Staygold-S2G10)-Nanobody(Staygold-S4F1), ZINC ION, ... | Authors: | Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. | Deposit date: | 2023-12-25 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the GFP:GFP-nanobody complex from Biortus. To Be Published
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8XKG
| Crystal structure of Acinetobacter baumannii IspD | Descriptor: | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, GLYCEROL | Authors: | Chen, X, Wu, D. | Deposit date: | 2023-12-23 | Release date: | 2024-04-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes. Int J Antimicrob Agents, 63, 2024
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8XKF
| Crystal structure of Helicobacter pylori IspDF with substrate CTP | Descriptor: | 1,2-ETHANEDIOL, Bifunctional enzyme IspD/IspF, CHLORIDE ION, ... | Authors: | Chen, X, Wu, D. | Deposit date: | 2023-12-23 | Release date: | 2024-04-10 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes. Int J Antimicrob Agents, 63, 2024
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8XK8
| N1D10 Fab bound to SFTSV glycoprotein-Gn | Descriptor: | Envelopment polyprotein, mAb N1D10 Fab heavy chain, mAb N1D10 Fab light chain | Authors: | Zhao, H, Deng, Z. | Deposit date: | 2023-12-22 | Release date: | 2024-07-10 | Last modified: | 2024-09-11 | Method: | X-RAY DIFFRACTION (3.53 Å) | Cite: | A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection. Nat Commun, 15, 2024
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8XK6
| S2A5 Fab bound to SFTSV glycoprotein Gn | Descriptor: | Envelopment polyprotein, mAb S2A5 Fab heavy chain, mAb S2A5 Fab light chain | Authors: | Deng, Z. | Deposit date: | 2023-12-22 | Release date: | 2024-07-10 | Last modified: | 2024-09-11 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection. Nat Commun, 15, 2024
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8XK5
| SNB1G11 Fab bound to SFTSV glycoprotein Gn | Descriptor: | Envelopment polyprotein, mAb SNB1G11 Fab heavy chain, mAb SNB1G11 Fab light chain | Authors: | Deng, Z. | Deposit date: | 2023-12-22 | Release date: | 2024-07-10 | Last modified: | 2024-09-11 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection. Nat Commun, 15, 2024
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