9GU1
 
 | | Human adult muscle nAChR in resting state in nanodisc with alpha-bungarotoxin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor subunit alpha, ... | | Authors: | Li, A, Pike, A.C.W, Chi, G, Webster, R, Maxwell, S, Liu, W, Beeson, D, Sauer, D.B, Dong, Y.Y. | | Deposit date: | 2024-09-18 | | Release date: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.48 Å) | | Cite: | Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states.
Cell Rep, 44, 2025
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9GU0
 | | Human adult muscle nAChR in resting state in detergent with alpha-bungarotoxin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Li, A, Pike, A.C.W, Chi, G, Webster, R, Maxwell, S, Liu, W, Beeson, D, Sauer, D.B, Dong, Y.Y. | | Deposit date: | 2024-09-18 | | Release date: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states.
Cell Rep, 44, 2025
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9GU2
 | | Human adult muscle nAChR in desensitised state in nanodisc with 100 uM acetylcholine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Li, A, Pike, A.C.W, Chi, G, Webster, R, Maxwell, S, Liu, W, Beeson, D, Sauer, D.B, Dong, Y.Y. | | Deposit date: | 2024-09-18 | | Release date: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states.
Cell Rep, 44, 2025
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8FCK
 | | Structure of the vertebrate augmin complex | | Descriptor: | HAUS augmin like complex subunit 2 L homeolog, Green fluorescent protein chimera, HAUS augmin like complex subunit 4 L homeolog, ... | | Authors: | Travis, S.M, Huang, W, Zhang, R, Petry, S. | | Deposit date: | 2022-12-01 | | Release date: | 2023-04-19 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (6.88 Å) | | Cite: | Integrated model of the vertebrate augmin complex.
Nat Commun, 14, 2023
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9BCF
 | | Chimeric protein of crocodile allergen Cro p 1.0101 and GFP | | Descriptor: | CALCIUM ION, Parvalbumin, Green fluorescent protein chimera | | Authors: | O'Malley, A, Ruethers, T, Lopata, A.L, Chruszcz, M. | | Deposit date: | 2024-04-09 | | Release date: | 2024-12-04 | | Last modified: | 2025-05-21 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Comparative studies of seafood and reptile alpha- and beta-parvalbumins.
Protein Sci., 33, 2024
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6L26
 | | Neutron crystal structure of the mutant green fluorescent protein (EGFP) | | Descriptor: | Green fluorescent protein, trideuteriooxidanium | | Authors: | Adachi, M, Shimizu, R, Shibazaki, C, Kagotani, Y, Ostermann, A, Schrader, T.E. | | Deposit date: | 2019-10-02 | | Release date: | 2020-04-08 | | Last modified: | 2025-01-01 | | Method: | NEUTRON DIFFRACTION (1.444 Å) | | Cite: | Direct Observation of the Protonation States in the Mutant Green Fluorescent Protein.
J Phys Chem Lett, 11, 2020
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8YA2
 | | Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+20C) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division protein FtsQ,Lactose permease, ... | | Authors: | Ou, X, Ma, C, Sun, D, Xu, J, Wu, X, Gao, N, Li, L. | | Deposit date: | 2024-02-07 | | Release date: | 2025-02-26 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | SecY translocon chaperones protein folding during membrane protein insertion.
Cell, 188, 2025
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8YA0
 | | Structure of the SecA-SecY complex with the substrate FtsQ-LacY(+7C) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division protein FtsQ,Lactose permease, ... | | Authors: | Ou, X, Ma, C, Sun, D, Xu, J, Wu, X, Gao, N, Li, L. | | Deposit date: | 2024-02-07 | | Release date: | 2025-02-26 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | SecY translocon chaperones protein folding during membrane protein insertion.
Cell, 188, 2025
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3EK4
 | | Calcium-saturated GCaMP2 Monomer | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | | Deposit date: | 2008-09-18 | | Release date: | 2008-12-16 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem., 284, 2009
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9C74
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9FQW
 | | Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the ornithine-bound inward-occluded state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, High affinity cationic amino acid transporter 1,Green fluorescent protein, ... | | Authors: | Ye, M, Zhou, D, Pike, A.C.W, Wang, S, Wang, D, Bakshi, S, Brooke, L, Williams, E, Elkins, J, Stuart, D.I, Sauer, D.B. | | Deposit date: | 2024-06-17 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus
To Be Published
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9FQU
 | | Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the arginine-bound inward-occluded state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARGININE, ... | | Authors: | Ye, M, Zhou, D, Pike, A.C.W, Wang, S, Wang, D, Bakshi, S, Brooke, L, Williams, E, Elkins, J, Stuart, D.I, Sauer, D.B. | | Deposit date: | 2024-06-17 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus
To Be Published
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9FQT
 | | Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the apo inward-open state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Ye, M, Zhou, D, Pike, A.C.W, Wang, S, Wang, D, Bakshi, S, Brooke, L, Williams, E, Elkins, J, Stuart, D.I, Sauer, D.B. | | Deposit date: | 2024-06-17 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus
To Be Published
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9FQV
 | | Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the lysine-bound inward-occluded state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, High affinity cationic amino acid transporter 1,Green fluorescent protein, ... | | Authors: | Ye, M, Zhou, D, Pike, A.C.W, Wang, S, Wang, D, Bakshi, S, Brooke, L, Williams, E, Elkins, J, Stuart, D.I, Sauer, D.B. | | Deposit date: | 2024-06-17 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Amino acid and viral binding by the high-affinity Cationic Amino acid Transporter 1 (CAT1) from Mus musculus
To Be Published
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7FHO
 | | Structure of AtTPC1 D240A/D454A/E528A mutant with 50 mM Ca2+ | | Descriptor: | CALCIUM ION, Two pore calcium channel protein 1,GFP | | Authors: | Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J. | | Deposit date: | 2021-07-29 | | Release date: | 2021-12-01 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7FHL
 | | Structure of AtTPC1 with 50 mM Ca2+ | | Descriptor: | AtTPC1-Cter, CALCIUM ION, Two pore calcium channel protein 1,GFP | | Authors: | Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J. | | Deposit date: | 2021-07-29 | | Release date: | 2021-12-01 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7FHK
 | | Structure of AtTPC1 with 1 mM Ca2+ | | Descriptor: | AtTPC1-Cter, CALCIUM ION, Two pore calcium channel protein 1,GFP | | Authors: | Ye, F, Xu, L, Li, X, Jiang, Y, Guo, J. | | Deposit date: | 2021-07-29 | | Release date: | 2021-12-01 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Voltage-gating and cytosolic Ca 2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6RMG
 | | Structure of PTCH1 bound to a modified Hedgehog ligand ShhN-C24II | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Korkhov, V.M, Qi, C. | | Deposit date: | 2019-05-06 | | Release date: | 2019-10-09 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis of sterol recognition by human hedgehog receptor PTCH1.
Sci Adv, 5, 2019
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6DEJ
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3WLD
 | | Crystal structure of monomeric GCaMP6m | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Ding, J, Luo, A.F, Hu, L.Y, Wang, D.C, Shao, F. | | Deposit date: | 2013-11-08 | | Release date: | 2014-01-22 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of the ultrasensitive calcium indicator GCaMP6.
Sci China Life Sci, 57, 2014
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3WLC
 | | Crystal structure of dimeric GCaMP6m | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Ding, J, Luo, A.F, Hu, L.Y, Wang, D.C, Shao, F. | | Deposit date: | 2013-11-08 | | Release date: | 2014-01-22 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structural basis of the ultrasensitive calcium indicator GCaMP6.
Sci China Life Sci, 57, 2014
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8TLM
 | | Structure of a class A GPCR/Fab complex | | Descriptor: | C-C chemokine receptor type 8, Green fluorescent protein fusion, Fab heavy chain, ... | | Authors: | Sun, D, Johnson, M, Masureel, M. | | Deposit date: | 2023-07-27 | | Release date: | 2023-12-20 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
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6F5J
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8KEX
 | | CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P, local | | Descriptor: | (4~{R})-4-[(3~{R},5~{R},8~{R},9~{S},10~{S},12~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-12-oxidanyl-3-phosphonooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoic acid, Soluble cytochrome b562,Mas-related G-protein coupled receptor member X4,Green fluorescent protein | | Authors: | Yang, J, Fan, J.P, Lei, X.G. | | Deposit date: | 2023-08-14 | | Release date: | 2024-11-06 | | Last modified: | 2024-12-25 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure-guided discovery of bile acid derivatives for treating liver diseases without causing itch.
Cell, 187, 2024
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8KB4
 | | Cryo-EM structure of human TMEM87A A308M | | Descriptor: | (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 87A,EGFP | | Authors: | Han, A, Kim, H.M. | | Deposit date: | 2023-08-03 | | Release date: | 2024-07-10 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | GolpHCat (TMEM87A), a unique voltage-dependent cation channel in Golgi apparatus, contributes to Golgi-pH maintenance and hippocampus-dependent memory.
Nat Commun, 15, 2024
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