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4M61
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BU of 4m61 by Molmil
Crystal structure of unliganded anti-DNA Fab A52
Descriptor: Fab A52 heavy chain, Fab A52 light chain, SULFATE ION
Authors:Stanfield, R.L, Eilat, D, Wilson, I.A.
Deposit date:2013-08-08
Release date:2013-08-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal structure determination of anti-DNA Fab A52.
Proteins, 82, 2014
6W35
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BU of 6w35 by Molmil
A new Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-fluoranyl-~{N}-[(2~{R})-1-[1-(2~{H}-indazol-5-yl)-3-methyl-2,4-bis(oxidanylidene)-1,3,8-triazaspiro[4.5]decan-8-yl]-3-methyl-1-oxidanylidene-butan-2-yl]-5-(trifluoromethyl)benzamide, CALCIUM ION, ...
Authors:Cuozzo, J.W.
Deposit date:2020-03-09
Release date:2020-07-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry.
J.Med.Chem., 63, 2020
2XQC
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BU of 2xqc by Molmil
DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE AND ZN
Descriptor: 5'-D(TP*TP*GP*AP*TP*GP)-3', DRA2 TRANSPOSASE LEFT END RECOGNITION SEQUENCE, TRANSPOSASE, ...
Authors:Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
Deposit date:2010-09-01
Release date:2010-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
1I6J
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BU of 1i6j by Molmil
CRYSTAL STRUCTURE OF A PSEUDO-16-MER DNA WITH STACKED GUANINES AND TWO G-A MISPAIRS COMPLEXED WITH THE N-TERMINAL FRAGMENT OF MOLONEY MURINE LEUKEMIA VIRUS REVERSE TRANSCRIPTASE
Descriptor: 5'-D(*AP*CP*GP*GP*GP*AP*CP*GP*AP*C)-3', 5'-D(*GP*TP*CP*GP*TP*C)-3', REVERSE TRANSCRIPTASE
Authors:Cote, M.L, Georgiadis, M.M.
Deposit date:2001-03-02
Release date:2001-09-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a pseudo-16-mer DNA with stacked guanines and two G-A mispairs complexed with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase.
Acta Crystallogr.,Sect.D, 57, 2001
1NAB
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BU of 1nab by Molmil
The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes
Descriptor: 5'-D(*CP*GP*AP*TP*CP*G)-3', 7-[5-(4-AMINO-5-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY)-4-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY]-6,9,11-TRIHYDROXY-9-(2-HYDROXY-ACETYL)-7,8,9,10-TETRAHYDRO-NAPHTHACENE-5,12-DIONE
Authors:Temperini, C, Messori, L, Orioli, P, Di Bugno, C, Animati, F, Ughetto, G.
Deposit date:2002-11-27
Release date:2003-02-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes
Nucleic Acids Res., 31, 2003
5OL5
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BU of 5ol5 by Molmil
Crystal structure of an inactivated Ssp SICLOPPS intein with CFAHPQ extein
Descriptor: 1,2-ETHANEDIOL, COBALT (II) ION, DNA polymerase III subunit alpha,DNA polymerase III subunit alpha, ...
Authors:Kick, L.M, Schneider, S.
Deposit date:2017-07-26
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.329 Å)
Cite:Mechanistic Insights into Cyclic Peptide Generation by DnaE Split-Inteins through Quantitative and Structural Investigation.
Chembiochem, 18, 2017
5E5S
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BU of 5e5s by Molmil
I-SmaMI K103A mutant
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Bottom strand DNA, DNA (5'-D(P*CP*AP*GP*GP*TP*GP*TP*AP*CP*G)-3'), ...
Authors:Shen, B.W.
Deposit date:2015-10-09
Release date:2016-01-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.
J.Mol.Biol., 428, 2016
3SSF
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BU of 3ssf by Molmil
Crystal structure of RNA:DNA dodecamer corresponding to HIV-1 polypurine tract, at 1.6 A resolution.
Descriptor: 5'-D(*CP*CP*TP*TP*TP*TP*CP*TP*TP*TP*TP*A)-3', 5'-R(*UP*AP*AP*AP*AP*GP*AP*AP*AP*AP*GP*G)-3', MAGNESIUM ION
Authors:Drozdzal, P, Michalska, K, Kierzek, R, Lomozik, L, Jaskolski, M.
Deposit date:2011-07-08
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of an RNA/DNA dodecamer corresponding to the HIV-1 polypurine tract at 1.6 Angstrom resolution
Acta Crystallogr.,Sect.D, 68, 2012
1RSB
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BU of 1rsb by Molmil
X-ray study of the DNA oligomer d(ATATAT) in P65 space group
Descriptor: 5'-D(*AP*TP*AP*TP*AP*T)-3'
Authors:Abrescia, N.G, Gonzalez, C, Gouyette, C, Subirana, J.A.
Deposit date:2003-12-09
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:X-ray and NMR studies of the DNA oligomer d(ATATAT): Hoogsteen base pairing in duplex DNA.
Biochemistry, 43, 2004
8VX9
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BU of 8vx9 by Molmil
Structure of HamAB apo complex from the Escherichia coli Hachiman defense system
Descriptor: HamA, HamB
Authors:Tuck, O.T, Doudna, J.A.
Deposit date:2024-02-03
Release date:2024-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Hachiman is a genome integrity sensor.
Biorxiv, 2024
2BAM
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BU of 2bam by Molmil
RESTRICTION ENDONUCLEASE BAMHI COMPLEX WITH DNA AND CALCIUM IONS (PRE-REACTIVE COMPLEX).
Descriptor: CALCIUM ION, DNA (5'-D(*TP*AP*TP*GP*GP*AP*TP*CP*CP*AP*TP*A)-3'), PROTEIN (ENDONUCLEASE BAMHI)
Authors:Viadiu, H, Aggarwal, A.K.
Deposit date:1998-08-19
Release date:1999-10-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of metals in catalysis by the restriction endonuclease BamHI.
Nat.Struct.Biol., 5, 1998
2XO6
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BU of 2xo6 by Molmil
DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE Y132F MUTANT COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE
Descriptor: 5'-D(*TP*TP*GP*AP*TP*G)-3', ACETATE ION, CADMIUM ION, ...
Authors:Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
Deposit date:2010-08-09
Release date:2010-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
4BG7
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BU of 4bg7 by Molmil
Bacteriophage T5 Homolog of the Eukaryotic Transcription Coactivator PC4 Implicated in Recombination-Dependent DNA Replication
Descriptor: PUTATIVE TRANSCRIPTIONAL COACTIVATOR P15
Authors:Steigemann, B, Schulz, A, Hinrichs, W, Werten, S.
Deposit date:2013-03-24
Release date:2013-09-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Bacteriophage T5 Encodes a Homolog of the Eukaryotic Transcription Coactivator Pc4 Implicated in Recombination-Dependent DNA Replication.
J.Mol.Biol., 425, 2013
5TRD
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BU of 5trd by Molmil
Structure of RbkR (Riboflavin Kinase) from Thermoplasma acidophilum determined in complex with CTP and its cognate DNA operator
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*TP*AP*CP*TP*AP*AP*TP*TP*CP*AP*CP*GP*AP*GP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*CP*TP*CP*GP*TP*GP*AP*AP*TP*TP*AP*GP*TP*AP*A)-3'), ...
Authors:Vetting, M.W, Rodionova, I.A, Li, X, Osterman, A.L, Rodionov, D.A, Almo, S.C.
Deposit date:2016-10-26
Release date:2016-11-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of RbkR (Riboflavin Kinase) from Thermoplasma acidophilum determined in complex with CTP and its cognate DNA operator
To be published
4HDV
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BU of 4hdv by Molmil
Crystal structure of S. pombe ATL1 in complex with damaged DNA containing 2,6-diaminopurine
Descriptor: 5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3', 5'-D(*GP*CP*CP*AP*TP*GP*(1AP)P*CP*TP*AP*GP*TP*A)-3', Alkyltransferase-like protein 1
Authors:Tubbs, J.L, Tainer, J.A.
Deposit date:2012-10-02
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-{pi} interactions.
Proc.Natl.Acad.Sci.USA, 109, 2012
2HXM
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BU of 2hxm by Molmil
Complex of UNG2 and a small Molecule synthetic Inhibitor
Descriptor: 4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID, Uracil-DNA glycosylase
Authors:Bianchet, M.A, Krosky, D.J, Ghung, S, Seiple, L, Amzel, L.M, Stivers, J.T.
Deposit date:2006-08-03
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Mimicking damaged DNA with a small molecule inhibitor of human UNG2.
Nucleic Acids Res., 34, 2006
4L6P
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BU of 4l6p by Molmil
Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair
Descriptor: GLYCEROL, Proliferating cell nuclear antigen
Authors:Washington, T, Boehm, E.
Deposit date:2013-06-12
Release date:2014-10-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair.
Biochemistry, 52, 2013
1Z1B
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BU of 1z1b by Molmil
Crystal structure of a lambda integrase dimer bound to a COC' core site
Descriptor: 26-MER DNA, 29-MER DNA, 5'-D(*CP*T*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', ...
Authors:Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T.
Deposit date:2005-03-03
Release date:2005-06-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A structural basis for allosteric control of DNA recombination by lambda integrase.
Nature, 435, 2005
384D
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BU of 384d by Molmil
HYDRATION AND RECOGNITION OF METHYLATED CPG STEPS IN DNA
Descriptor: 5'-D(*CP*(5CM)P*GP*CP*(5CM)P*GP*GP*(5CM)P*GP*G)-3', MAGNESIUM ION
Authors:Mayer-Jung, C, Moras, D, Timsit, Y.
Deposit date:1998-03-02
Release date:1998-03-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Hydration and Recognition of Methylated CpG Steps in DNA
Embo J., 17, 1998
2ZXO
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BU of 2zxo by Molmil
Crystal structure of RecJ from Thermus thermophilus HB8
Descriptor: Single-stranded DNA specific exonuclease RecJ
Authors:Wakamatsu, T, Kitamura, Y, Nakagawa, N, Masui, R, Kuramitsu, S.
Deposit date:2009-01-05
Release date:2010-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of RecJ exonuclease defines its specificity for single-stranded DNA
J.Biol.Chem., 285, 2010
1RPZ
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BU of 1rpz by Molmil
T4 POLYNUCLEOTIDE KINASE BOUND TO 5'-TGCAC-3' SSDNA
Descriptor: 5'-D(*TP*GP*CP*AP*C)-3', ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Eastberg, J.H, Pelletier, J, Stoddard, B.L.
Deposit date:2003-12-03
Release date:2004-02-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase.
Nucleic Acids Res., 32, 2004
4HDU
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BU of 4hdu by Molmil
Crystal structure of S. pombe ATL1 in complex with damaged DNA containing 2-aminopurine
Descriptor: 5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3', 5'-D(*GP*CP*CP*AP*TP*GP*(2PR)P*CP*TP*AP*GP*TP*A)-3', Alkyltransferase-like protein 1
Authors:Tubbs, J.L, Tainer, J.A.
Deposit date:2012-10-02
Release date:2012-12-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.848 Å)
Cite:Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-{pi} interactions.
Proc.Natl.Acad.Sci.USA, 109, 2012
2ZXP
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BU of 2zxp by Molmil
Crystal structure of RecJ in complex with Mn2+ from Thermus thermophilus HB8
Descriptor: MANGANESE (II) ION, Single-stranded DNA specific exonuclease RecJ
Authors:Wakamatsu, T, Kitamura, Y, Nakagawa, N, Masui, R, Kuramitsu, S.
Deposit date:2009-01-05
Release date:2010-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of RecJ exonuclease defines its specificity for single-stranded DNA
J.Biol.Chem., 285, 2010
2ZXR
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Crystal structure of RecJ in complex with Mg2+ from Thermus thermophilus HB8
Descriptor: MAGNESIUM ION, Single-stranded DNA specific exonuclease RecJ
Authors:Wakamatsu, T, Kitamura, Y, Nakagawa, N, Masui, R, Kuramitsu, S.
Deposit date:2009-01-05
Release date:2010-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of RecJ exonuclease defines its specificity for single-stranded DNA
J.Biol.Chem., 285, 2010
1RRC
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BU of 1rrc by Molmil
T4 POLYNUCLEOTIDE KINASE BOUND TO 5'-GTC-3' SSDNA
Descriptor: 5'-D(*GP*TP*C)-3', ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Eastberg, J.H, Pelletier, J, Stoddard, B.L.
Deposit date:2003-12-08
Release date:2004-02-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase.
Nucleic Acids Res., 32, 2004

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