4HDU

Crystal structure of S. pombe ATL1 in complex with damaged DNA containing 2-aminopurine

Summary for 4HDU

• Entry DOI: 10.2210/pdb4hdu/pdb
• Related: 4HDV
• Descriptor: Alkyltransferase-like protein 1, 5'-D(*GP*CP*CP*AP*TP*GP*(2PR)P*CP*TP*AP*GP*TP*A)-3', 5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3' (3 entities in total)
• Functional Keywords: alkyltransferase, dna repair, nucleotide excision repair, ner, base repair, dna damage, guanine, alkylation, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Schizosaccharomyces pombe (Fission yeast)
• Total number of polymer chains: 3
• Total formula weight: 21589.61

Authors

Tubbs, J.L.,Tainer, J.A. (deposition date: 2012-10-02, release date: 2012-12-26, Last modification date: 2023-09-20)

• Primary citation: Wilkinson, O.J.,Latypov, V.,Tubbs, J.L.,Millington, C.L.,Morita, R.,Blackburn, H.,Marriott, A.,McGown, G.,Thorncroft, M.,Watson, A.J.,Connolly, B.A.,Grasby, J.A.,Masui, R.,Hunter, C.A.,Tainer, J.A.,Margison, G.P.,Williams, D.M.; Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-{pi} interactions.; Proc.Natl.Acad.Sci.USA, 109:18755-18760, 2012; PubMed: 23112169; DOI: 10.1073/pnas.1209451109

Experimental method

X-RAY DIFFRACTION (2.848 Å)