1WJO
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![BU of 1wjo by Molmil](/molmil-images/mine/1wjo) | Solution structure of the forth CH domain from human plastin 3 T-isoform | Descriptor: | T-plastin | Authors: | Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-29 | Release date: | 2004-11-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the forth CH domain from human plastin 3 T-isoform To be Published
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6X2U
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![BU of 6x2u by Molmil](/molmil-images/mine/6x2u) | Crystal Structure of PKINES peptide bound to CRM1 | Descriptor: | Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ... | Authors: | Baumhardt, J.M. | Deposit date: | 2020-05-21 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation. Mol.Biol.Cell, 31, 2020
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6YLH
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![BU of 6ylh by Molmil](/molmil-images/mine/6ylh) | |
6XJP
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6XJX
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![BU of 6xjx by Molmil](/molmil-images/mine/6xjx) | MCU holocomplex in Low-calcium blocking state | Descriptor: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | Authors: | Wang, Y, Jiang, Y. | Deposit date: | 2020-06-24 | Release date: | 2020-09-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter. Elife, 9, 2020
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6XJT
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![BU of 6xjt by Molmil](/molmil-images/mine/6xjt) | Crystal Structure of KPT-8602 bound to CRM1 (537-DLTVK-541 to GLCEQ) | Descriptor: | (2R)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)propanamide, Exportin-1, GTP-binding nuclear protein Ran, ... | Authors: | Baumhardt, J.M, Chook, Y.M. | Deposit date: | 2020-06-24 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.406 Å) | Cite: | Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia. J Hematol Oncol, 14, 2021
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7S4E
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1RRG
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![BU of 1rrg by Molmil](/molmil-images/mine/1rrg) | NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, DIMERIC CRYSTAL FORM | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAT ADP-RIBOSYLATION FACTOR-1 | Authors: | Greasley, S.E, Jhoti, H, Bax, B. | Deposit date: | 1995-12-16 | Release date: | 1996-06-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms. Nat.Struct.Biol., 2, 1995
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1RRF
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![BU of 1rrf by Molmil](/molmil-images/mine/1rrf) | NON-MYRISTOYLATED RAT ADP-RIBOSYLATION FACTOR-1 COMPLEXED WITH GDP, MONOMERIC CRYSTAL FORM | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAT ADP-RIBOSYLATION FACTOR-1 | Authors: | Greasley, S.E, Jhoti, H, Bax, B. | Deposit date: | 1995-12-16 | Release date: | 1996-06-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms. Nat.Struct.Biol., 2, 1995
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1S1C
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![BU of 1s1c by Molmil](/molmil-images/mine/1s1c) | Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rho-associated, ... | Authors: | Dvorsky, R, Blumenstein, L, Vetter, I.R, Ahmadian, M.R. | Deposit date: | 2004-01-06 | Release date: | 2004-02-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA. J.Biol.Chem., 279, 2004
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1TX4
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![BU of 1tx4 by Molmil](/molmil-images/mine/1tx4) | RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, P50-RHOGAP, ... | Authors: | Rittinger, K, Walker, P.A, Smerdon, S.J, Gamblin, S.J. | Deposit date: | 1997-07-29 | Release date: | 1998-09-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature, 389, 1997
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6LAG
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![BU of 6lag by Molmil](/molmil-images/mine/6lag) | Solution structure of SPA-2 SHD | Descriptor: | Spa2-like protein | Authors: | Fan, J.S, Wong, J.Y, Zheng, P, Yang, D, Jedd, G. | Deposit date: | 2019-11-12 | Release date: | 2020-04-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Spitzenkorper assembly mechanisms reveal conserved features of fungal and metazoan polarity scaffolds. Nat Commun, 11, 2020
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2MYO
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![BU of 2myo by Molmil](/molmil-images/mine/2myo) | SOLUTION STRUCTURE OF MYOTROPHIN, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | MYOTROPHIN | Authors: | Yang, Y, Nanduri, S, Sen, S, Qin, J. | Deposit date: | 1998-08-17 | Release date: | 1999-08-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structural basis of ankyrin-like repeat function as revealed by the solution structure of myotrophin. Structure, 6, 1998
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1X86
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4E17
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![BU of 4e17 by Molmil](/molmil-images/mine/4e17) | Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin | Descriptor: | Catenin alpha-1, Vinculin | Authors: | Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. | Deposit date: | 2012-03-05 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin To be Published
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2KR3
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![BU of 2kr3 by Molmil](/molmil-images/mine/2kr3) | Solution structure of SHA-D | Descriptor: | Spectrin alpha chain, brain | Authors: | Khristoforov, V.S, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Filimonov, V.V, Kutyshenko, V.P. | Deposit date: | 2009-12-03 | Release date: | 2010-09-15 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Chimeric SHA-D domain "SH3-Bergerac": 3D structure and dynamics studies Russ.J.Bioorganic Chem., 36, 2010
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1T01
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![BU of 1t01 by Molmil](/molmil-images/mine/1t01) | Vinculin complexed with the VBS1 helix from talin | Descriptor: | Talin 1, unnamed protein product | Authors: | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | Deposit date: | 2004-04-07 | Release date: | 2004-08-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle Embo J., 23, 2004
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2O0A
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![BU of 2o0a by Molmil](/molmil-images/mine/2o0a) | The structure of the C-terminal domain of Vik1 has a motor domain fold but lacks a nucleotide-binding site. | Descriptor: | 1,2-ETHANEDIOL, S.cerevisiae chromosome XVI reading frame ORF YPL253c | Authors: | Allingham, J.S, Sproul, L.R, Rayment, I, Gilbert, S.P. | Deposit date: | 2006-11-27 | Release date: | 2007-03-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Vik1 modulates microtubule-Kar3 interactions through a motor domain that lacks an active site. Cell(Cambridge,Mass.), 128, 2007
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3WIM
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![BU of 3wim by Molmil](/molmil-images/mine/3wim) | GABARAP-LIR peptide complex | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, WD repeat and FYVE domain-containing protein 3 | Authors: | Lystad, A, Ichimura, Y, Takagi, K, Yang, Y, Pankiv, S, Mizushima, T, Komatsu, M, Simonsen, A. | Deposit date: | 2013-09-19 | Release date: | 2014-03-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | GABARAP-LIR peptide complex To be Published, 2014
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2ANG
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![BU of 2ang by Molmil](/molmil-images/mine/2ang) | CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN OF THE MET(-1) FORM | Descriptor: | ANGIOGENIN, CITRIC ACID | Authors: | Leonidas, D.D, Allen, S.C, Acharya, K.R. | Deposit date: | 1998-11-12 | Release date: | 1999-04-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J.Mol.Biol., 285, 1999
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2B7B
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![BU of 2b7b by Molmil](/molmil-images/mine/2b7b) | Yeast guanine nucleotide exchange factor eEF1Balpha K205A mutant in complex with eEF1A and GDP | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, elongation factor-1 beta | Authors: | Pittman, Y.R, Valente, L, Jeppesen, M.G, Andersen, G.R, Patel, S, Kinzy, T.G. | Deposit date: | 2005-10-04 | Release date: | 2006-05-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Mg2+ and a key lysine modulate exchange activity of eukaryotic translation elongation factor 1B alpha J.Biol.Chem., 281, 2006
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2B86
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1KMQ
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![BU of 1kmq by Molmil](/molmil-images/mine/1kmq) | Crystal Structure of a Constitutively Activated RhoA Mutant (Q63L) | Descriptor: | 1,4-DIETHYLENE DIOXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Longenecker, K, Read, P, Lin, S.-K, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S. | Deposit date: | 2001-12-17 | Release date: | 2003-05-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 A resolution. Acta Crystallogr.,Sect.D, 59, 2003
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1LB1
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![BU of 1lb1 by Molmil](/molmil-images/mine/1lb1) | Crystal Structure of the Dbl and Pleckstrin homology domains of Dbs in complex with RhoA | Descriptor: | Guanine nucleotide exchange factor DBS, Transforming protein RhoA | Authors: | Snyder, J.T, Worthylake, D.K, Rossman, K.L, Betts, L, Pruitt, W.M, Siderovski, D.P, Der, C.J, Sondek, J. | Deposit date: | 2002-04-01 | Release date: | 2002-05-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat.Struct.Biol., 9, 2002
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2ALD
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![BU of 2ald by Molmil](/molmil-images/mine/2ald) | HUMAN MUSCLE ALDOLASE | Descriptor: | FRUCTOSE-BISPHOSPHATE ALDOLASE | Authors: | Dalby, A.R, Littlechild, J.A. | Deposit date: | 1998-10-21 | Release date: | 1999-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications. Protein Sci., 8, 1999
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