2MQF
| NMR structure of spider toxin-TRTX-Hhn2b | Descriptor: | Mu-theraphotoxin-Hhn2b | Authors: | Klint, J.K, Chin, Y.K.Y, Mobli, M. | Deposit date: | 2014-06-19 | Release date: | 2015-07-15 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7 Mol.Pharmacol., 88, 2015
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2N6O
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2MXM
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2MPQ
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6W6O
| NaChBac-Nav1.7VSDII chimera and HWTX-IV complex | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Huwentoxin-IV, NaChBac-Nav1.7VSDII chimera | Authors: | Yan, N, Gao, S. | Deposit date: | 2020-03-17 | Release date: | 2020-06-24 | Last modified: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na + channels in nanodisc. Proc.Natl.Acad.Sci.USA, 117, 2020
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7K48
| Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Ion transport protein,Sodium channel protein type 9 subunit alpha chimera, Mu-theraphotoxin-Hs2a | Authors: | Wisedchaisri, G, Tonggu, L, Gamal El-Din, T.M, McCord, E, Zheng, N, Catterall, W.A. | Deposit date: | 2020-09-15 | Release date: | 2020-12-02 | Last modified: | 2021-01-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Basis for High-Affinity Trapping of the Na V 1.7 Channel in Its Resting State by Tarantula Toxin. Mol.Cell, 81, 2021
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3J5Q
| Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy | Descriptor: | Kappa-theraphotoxin-Cg1a 1, Transient receptor potential cation channel subfamily V member 1 | Authors: | Liao, M, Cao, E, Julius, D, Cheng, Y. | Deposit date: | 2013-10-28 | Release date: | 2013-12-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | TRPV1 structures in distinct conformations reveal activation mechanisms. Nature, 504, 2013
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