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2J9H
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BU of 2j9h by Molmil
Crystal structure of human glutathione-S-transferase P1-1 cys-free mutant in complex with S-hexylglutathione at 2.4 A resolution
Descriptor: GLUTATHIONE S-TRANSFERASE P, S-HEXYLGLUTATHIONE
Authors:Tars, K, Hegazy, U.M, Hellman, U, Mannervik, B.
Deposit date:2006-11-08
Release date:2006-11-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Modulating Catalytic Activity by Unnatural Amino Acid Residues in a Gsh-Binding Loop of Gst P1-1.
J.Mol.Biol., 376, 2008
2GSQ
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BU of 2gsq by Molmil
GLUTATHIONE S-TRANSFERASE FROM SQUID DIGESTIVE GLAND COMPLEXED WITH S-(3-IODOBENZYL)GLUTATHIONE
Descriptor: GLUTATHIONE S-TRANSFERASE, S-(3-IODOBENZYL)GLUTATHIONE, SULFATE ION
Authors:Ji, X, Armstrong, R.N, Gilliland, G.L.
Deposit date:1995-04-14
Release date:1996-04-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Location of a potential transport binding site in a sigma class glutathione transferase by x-ray crystallography.
Proc.Natl.Acad.Sci.USA, 93, 1996
2OAD
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BU of 2oad by Molmil
Structure of Glutathione-S-Transferase C169A Mutant
Descriptor: Glutathione S-transferase P 1, S-(P-NITROBENZYL)GLUTATHIONE
Authors:Kyrieleis, O.J, McManus, G, Mantle, T.J, Khan, A.R.
Deposit date:2006-12-15
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Kinetic Analyses of Glutathione S-Transferase Mutations
TO BE PUBLISHED
2OAC
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BU of 2oac by Molmil
Mouse C14A Glutathione-S-Transferase Mutant in Complex with S-(p-nitrobenzyl) Glutathione
Descriptor: Glutathione S-transferase P 1, S-(P-NITROBENZYL)GLUTATHIONE
Authors:Kyrieleis, O.J, McManus, G, Mantle, T.J, Khan, A.R.
Deposit date:2006-12-15
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Kinetic Analyses of Glutathione S-Transferase Mutants
TO BE PUBLISHED
3N9J
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BU of 3n9j by Molmil
Structure of human Glutathione Transferase Pi class in complex with Ethacraplatin
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Parker, L.J, Parker, M.W.
Deposit date:2010-05-30
Release date:2011-05-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.
To be Published
2ON5
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BU of 2on5 by Molmil
Structure of NaGST-2
Descriptor: 1,2-ETHANEDIOL, GLUTATHIONE, Na Glutathione S-transferase 2
Authors:Asojo, O.A, Ngamelue, M, Homma, H, Goud, G, Zhan, B, Hotez, P.J.
Deposit date:2007-01-23
Release date:2007-08-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structures of Na-GST-1 and Na-GST-2 two glutathione s-transferase from the human hookworm Necator americanus
Bmc Struct.Biol., 7, 2007
2GLR
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BU of 2glr by Molmil
MOLECULAR STRUCTURE AT 1.8 ANGSTROMS OF MOUSE LIVER CLASS PI GLUTATHIONE S-TRANSFERASE COMPLEXED WITH S-(P-NITROBENZYL)GLUTATHIONE AND OTHER INHIBITORS
Descriptor: GLUTATHIONE S-TRANSFERASE YFYF, S-HEXYLGLUTATHIONE
Authors:Parraga, A, Garcia-Saez, I, Coll, M.
Deposit date:1994-05-04
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular structure at 1.8 A of mouse liver class pi glutathione S-transferase complexed with S-(p-nitrobenzyl)glutathione and other inhibitors.
J.Mol.Biol., 237, 1994
3O76
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1.8 Angstroms molecular structure of mouse liver glutathione S-transferase mutant C47A complexed with S-(P-nitrobenzyl)glutathione
Descriptor: Glutathione S-transferase P 1, S-(P-NITROBENZYL)GLUTATHIONE
Authors:Canals, A, Coll, M.
Deposit date:2010-07-30
Release date:2011-06-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked cooperativity, introduces a novel mechanism for 'ping pong' kinetic behaviour, and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione.
Febs J., 278, 2011
2OA7
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BU of 2oa7 by Molmil
Mouse C14A Glutathione-S-Transferase Mutant in Complex with S-hexyl glutathione
Descriptor: Glutathione S-transferase P 1, S-HEXYLGLUTATHIONE
Authors:Kyrieleis, O.J, McManus, G, Mantle, T.J, Khan, A.R.
Deposit date:2006-12-15
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mouse C14A Glutathione-S-Transferase Mutant in Complex with S-hexyl glutathione
TO BE PUBLISHED
2PGT
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BU of 2pgt by Molmil
CRYSTAL STRUCTURE OF HUMAN GLUTATHIONE S-TRANSFERASE P1-1[V104] COMPLEXED WITH (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE
Descriptor: (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE, ...
Authors:Ji, X.
Deposit date:1997-02-17
Release date:1997-09-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class pi glutathione S-transferase.
Biochemistry, 36, 1997
4GF0
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Crystal structure of glutahtione transferase homolog from sulfitobacter, TARGET EFI-501084, with bound glutathione
Descriptor: CHLORIDE ION, GLUTATHIONE, Glutathione S-transferase
Authors:Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
Deposit date:2012-08-02
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of glutahtione transferase homolog from sulfitobacter, TARGET EFI-501084, with bound glutathione
To be Published
4GSS
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BU of 4gss by Molmil
HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y108F MUTANT
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE
Authors:Oakley, A, Rossjohn, J, Parker, M.
Deposit date:1997-01-20
Release date:1998-01-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme.
Biochemistry, 36, 1997
4IGJ
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BU of 4igj by Molmil
Crystal structure of Maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, target EFI-507175
Descriptor: Maleylacetoacetate isomerase, SULFATE ION
Authors:Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C.
Deposit date:2012-12-17
Release date:2013-01-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structure of Maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, target EFI-507175
To be Published
4EC0
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BU of 4ec0 by Molmil
Crystal structure of hH-PGDS with water displacing inhibitor
Descriptor: 4-[2-(aminomethyl)naphthalen-1-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide, GLUTATHIONE, Hematopoietic prostaglandin D synthase, ...
Authors:Day, J.E, Thorarensen, A, Trujillo, J.I.
Deposit date:2012-03-26
Release date:2012-05-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters.
Bioorg.Med.Chem.Lett., 22, 2012
4EE0
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BU of 4ee0 by Molmil
Crystal structure of hH-PGDS with water displacing inhibitor
Descriptor: 4-(isoquinolin-1-yl)-N-[2-(morpholin-4-yl)ethyl]benzamide, Hematopoietic prostaglandin D synthase, L-GAMMA-GLUTAMYL-3-SULFINO-L-ALANYLGLYCINE, ...
Authors:Day, J.E, Thorarensen, A, Trujillo, J.I.
Deposit date:2012-03-28
Release date:2012-07-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters.
Bioorg.Med.Chem.Lett., 22, 2012
4ECC
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BU of 4ecc by Molmil
Chimeric GST Containing Inserts of Kininogen Peptides
Descriptor: chimeric protein between GSHKT10 and domain 5 of kininogen-1
Authors:Amber, A.B, Sergei, M.M, Yi, P, Rita, R, Xiaoping, Q, Marianne, P.-C, William, C.M, Vivien, Y, Keith, R.M, Anton, A.K.
Deposit date:2012-03-26
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chimeric glutathione S-transferases containing inserts of kininogen peptides: potential novel protein therapeutics.
J.Biol.Chem., 287, 2012
4CHS
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BU of 4chs by Molmil
Crystal structure of a tau class glutathione transferase 10 from Glycine max
Descriptor: ACETONE, GLUTATHIONE S-TRANSFERASE, S-Hydroxy-Glutathione
Authors:Skopelitou, K, Muleta, A.W, Papageorgiou, A.C, Pavli, O, Flemetakis, E, Chronopoulou, E, Skaracis, G.N, Labrou, N.E.
Deposit date:2013-12-04
Release date:2014-12-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Catalytic features and crystal structure of a tau class glutathione transferase from Glycine max specifically upregulated in response to soybean mosaic virus infections.
Biochim. Biophys. Acta, 1854, 2015
4EDZ
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BU of 4edz by Molmil
Crystal structure of hH-PGDS with water displacing inhibitor
Descriptor: 4-(3-methylisoquinolin-1-yl)-N-[2-(morpholin-4-yl)ethyl]benzamide, GLUTATHIONE, Hematopoietic prostaglandin D synthase, ...
Authors:Day, J.E, Thorarensen, A, Trujillo, J.I.
Deposit date:2012-03-27
Release date:2012-05-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters.
Bioorg.Med.Chem.Lett., 22, 2012
4ECB
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BU of 4ecb by Molmil
Chimeric GST Containing Inserts of Kininogen Peptides
Descriptor: chimeric protein between GSHKT10 and domain 5 of kininogen-1
Authors:Amber, A.B, Sergei, M.M, Yi, P, Rita, R, Xiaoping, Q, Marianne, P.-C, William, C.M, Vivien, Y, Keith, R.M, Anton, A.K.
Deposit date:2012-03-26
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Chimeric glutathione S-transferases containing inserts of kininogen peptides: potential novel protein therapeutics.
J.Biol.Chem., 287, 2012
4EDY
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BU of 4edy by Molmil
Crystal structure of hH-PGDS with water displacing inhibitor
Descriptor: 4-[2-(hydroxymethyl)naphthalen-1-yl]-N-[2-(morpholin-4-yl)ethyl]benzamide, DIMETHYL SULFOXIDE, GLUTATHIONE, ...
Authors:Day, J.E, Thorarensen, A, Trujillo, J.I, Kiefer, J.R.
Deposit date:2012-03-27
Release date:2012-10-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters.
Bioorg.Med.Chem.Lett., 22, 2012
5G5A
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BU of 5g5a by Molmil
Glutathione transferase U25 from Arabidopsis thaliana in complex with glutathione disulfide
Descriptor: GLUTATHIONE, GLUTATHIONE S-TRANSFERASE U25
Authors:Ahmad, L, Rylott, E, Bruce, N.C, Grogan, G.
Deposit date:2016-05-23
Release date:2017-06-07
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of Glutathione Transferase U25 from Arabidopsis Thaliana
To be Published
4KH7
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Crystal structure of a glutathione transferase family member from salmonella enterica ty2, target efi-507262, with bound glutathione
Descriptor: GLUTATHIONE, Glutathione s-transferase family protein
Authors:Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI)
Deposit date:2013-04-30
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of a glutathione transferase family member from Salmonella enterica ty2, target efi-507262, with bound glutathione
To be published
4L5O
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BU of 4l5o by Molmil
Crystal structure of 26 kDa GST D26H mutant of Clonorchis sinensis
Descriptor: GLUTATHIONE, Putative glutathione transferase, SULFATE ION, ...
Authors:Chung, Y.J, Han, Y.H.
Deposit date:2013-06-11
Release date:2013-09-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal structures of 26kDa Clonorchis sinensis glutathione S-transferase reveal zinc binding and putative metal binding.
Biochem.Biophys.Res.Commun., 438, 2013
5GZZ
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BU of 5gzz by Molmil
Crystal Structure of FIN219-SjGST complex with JA
Descriptor: GLUTATHIONE, Glutathione S-transferase class-mu 26 kDa isozyme, Jasmonic acid-amido synthetase JAR1, ...
Authors:Chen, C.Y, Cheng, Y.S.
Deposit date:2016-10-02
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.386 Å)
Cite:Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4L5L
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BU of 4l5l by Molmil
Crystal structure of 26 kDa GST of Clonorchis sinensis in P212121 symmetry
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Putative glutathione transferase, ...
Authors:Chung, Y.J, Han, Y.H.
Deposit date:2013-06-11
Release date:2013-09-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of 26kDa Clonorchis sinensis glutathione S-transferase reveal zinc binding and putative metal binding.
Biochem.Biophys.Res.Commun., 438, 2013

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