4ECC

Chimeric GST Containing Inserts of Kininogen Peptides

Summary for 4ECC

Related4ECB
Descriptorchimeric protein between GSHKT10 and domain 5 of kininogen-1 (2 entities in total)
Functional Keywordsgst, domain 5 of human high molecular weight kininogen, biosynthetic protein, transferase, protein binding
Biological sourceSchistosoma japonicum (Blood fluke, human)
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Total number of polymer chains1
Total molecular weight26946.35
Authors
Amber, A.B.,Sergei, M.M.,Yi, P.,Rita, R.,Xiaoping, Q.,Marianne, P.-C.,William, C.M.,Vivien, Y.,Keith, R.M.,Anton, A.K. (deposition date: 2012-03-26, release date: 2012-05-16, Last modification date: 2017-08-09)
Primary citation
Bentley, A.A.,Merkulov, S.M.,Peng, Y.,Rozmarynowycz, R.,Qi, X.,Pusztai-Carey, M.,Merrick, W.C.,Yee, V.C.,McCrae, K.R.,Komar, A.A.
Chimeric glutathione S-transferases containing inserts of kininogen peptides: potential novel protein therapeutics.
J.Biol.Chem., 287:22142-22150, 2012
PubMed: 22577144 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M112.372854
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.270401.6%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution