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4A6N
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BU of 4a6n by Molmil
STRUCTURE OF THE TETRACYCLINE DEGRADING MONOOXYGENASE TETX IN COMPLEX WITH TIGECYCLINE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TETX2 PROTEIN, ...
Authors:Volkers, G, Palm, G.J, Weiss, M.S, Hinrichs, W.
Deposit date:2011-11-07
Release date:2012-11-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Putative Dioxygen-Binding Sites and Recognition of Tigecycline and Minocycline in the Tetracycline-Degrading Monooxygenase Tetx
Acta Crystallogr.,Sect.D, 69, 2013
3V3O
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BU of 3v3o by Molmil
Crystal structure of TetX2 T280A: an adaptive mutant in complex with tigecycline
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TIGECYCLINE, ...
Authors:Walkiewicz, K, Shamoo, Y.
Deposit date:2011-12-13
Release date:2013-01-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of TetX2 T280A: an adaptive mutant in complex with tigecycline
To be Published
2PHH
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BU of 2phh by Molmil
THE COENZYME ANALOGUE ADENOSINE 5-DIPHOSPHORIBOSE DISPLACES FAD IN THE ACTIVE SITE OF P-HYDROXYBENZOATE HYDROXYLASE. AN X-RAY CRYSTALLOGRAPHIC INVESTIGATION
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID
Authors:Van Derlaan, J.M, Drenth, J, Hol, W.G.J.
Deposit date:1989-06-19
Release date:1990-10-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation.
Biochemistry, 28, 1989
2BRA
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BU of 2bra by Molmil
Structure of N-Terminal FAD Binding motif of mouse MICAL
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NEDD9 INTERACTING PROTEIN WITH CALPONIN HOMOLOGY AND LIM DOMAINS
Authors:Nadella, M, Bianchet, M.A, Gabelli, S.B, Amzel, L.M.
Deposit date:2005-05-04
Release date:2005-11-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and activity of the axon guidance protein MICAL.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
6PVG
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BU of 6pvg by Molmil
Crystal structure of ligand free PhqK
Descriptor: FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Fraley, A.E, Smith, J.L, Sherman, D.H.
Deposit date:2019-07-20
Release date:2020-01-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.709 Å)
Cite:Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
J.Am.Chem.Soc., 142, 2020
6PVI
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BU of 6pvi by Molmil
Crystal structure of PhqK in complex with paraherquamide L
Descriptor: (8aS,13S,13aR,14aS)-4,4,13,15,15-pentamethyl-12,13,14,14a,15,16-hexahydro-4H,8H,9H,11H-8a,13a-(epiminomethano)[1,4]dioxepino[2,3-a]indolizino[6,7-h]carbazol-17-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Fraley, A.E, Smith, J.L, Sherman, D.H.
Deposit date:2019-07-20
Release date:2020-01-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
J.Am.Chem.Soc., 142, 2020
6PVF
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BU of 6pvf by Molmil
Crystal structure of PhqK in complex with malbrancheamide B
Descriptor: (5aS,12aS,13aS)-9-chloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Fraley, A.E, Smith, J.L, Sherman, D.H.
Deposit date:2019-07-20
Release date:2020-01-22
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
J.Am.Chem.Soc., 142, 2020
6PVH
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BU of 6pvh by Molmil
Crystal structure of PhqK in complex with paraherquamide K
Descriptor: (7aS,12S,12aR,13aS)-3,3,12,14,14-pentamethyl-3,7,11,12,13,13a,14,15-octahydro-8H,10H-7a,12a-(epiminomethano)indolizino[6,7-h]pyrano[3,2-a]carbazol-16-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Fraley, A.E, Smith, J.L, Sherman, D.H.
Deposit date:2019-07-20
Release date:2020-01-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
J.Am.Chem.Soc., 142, 2020
6PVJ
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BU of 6pvj by Molmil
Crystal structure of PhqK in complex with malbrancheamide C
Descriptor: (5aS,12aS,13aS)-9-bromo-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Fraley, A.E, Smith, J.L, Sherman, D.H.
Deposit date:2019-07-20
Release date:2020-01-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
J.Am.Chem.Soc., 142, 2020
2BRY
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BU of 2bry by Molmil
Crystal structure of the native monooxygenase domain of MICAL at 1.45 A resolution
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Siebold, C, Berrow, N, Walter, T.S, Harlos, K, Owens, R.J, Terman, J.R, Stuart, D.I, Kolodkin, A.L, Pasterkamp, R.J, Jones, E.Y.
Deposit date:2005-05-13
Release date:2005-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-Resolution Structure of the Catalytic Region of Mical (Molecule Interacting with Casl), a Multidomain Flavoenzyme-Signaling Molecule.
Proc.Natl.Acad.Sci.USA, 102, 2005
2C4C
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BU of 2c4c by Molmil
Crystal structure of the NADPH-treated monooxygenase domain of MICAL
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NEDD9-INTERACTING PROTEIN WITH CALPONIN HOMOLOGY AND LIM DOMAINS
Authors:Siebold, C, Berrow, N, Walter, T.S, Harlos, K, Owens, R.J, Terman, J.R, Stuart, D.I, Kolodkin, A.L, Pasterkamp, R.J, Jones, E.Y.
Deposit date:2005-10-18
Release date:2005-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:High-Resolution Structure of the Catalytic Region of Mical (Molecule Interacting with Casl), a Multidomain Flavoenzyme-Signaling Molecule.
Proc.Natl.Acad.Sci.USA, 102, 2005
6LKE
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BU of 6lke by Molmil
in meso full-length rat KMO in complex with an inhibitor identified via DNA-encoded chemical library screening
Descriptor: 4-chloranyl-2-[[5-chloranyl-2-(5-methoxy-1,3-dihydroisoindol-2-yl)-1,3-thiazol-4-yl]carbonyl-methyl-amino]-5-fluoranyl-benzoic acid, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Mimasu, S, Yamagishi, H, Kiyohara, M, Hupp, D.C, Liu, J, Kakefuda, K, Okuda, T.
Deposit date:2019-12-19
Release date:2020-12-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition.
Commun Biol, 4, 2021
5Y66
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BU of 5y66 by Molmil
Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN and Ro61-8048
Descriptor: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xiang, Y, Gao, J.J, Zhu, D.Y.
Deposit date:2017-08-10
Release date:2017-12-27
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048
FASEB J., 32, 2018
5Y7A
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BU of 5y7a by Molmil
Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN
Descriptor: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Xiang, Y, Gao, J.J, Zhu, D.Y.
Deposit date:2017-08-16
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.846 Å)
Cite:Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048
FASEB J., 32, 2018
5Y77
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BU of 5y77 by Molmil
Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN (seMet derivative)
Descriptor: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
Authors:Xiang, Y, Gao, J.J, Zhu, D.Y.
Deposit date:2017-08-16
Release date:2017-12-27
Last modified:2018-04-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048
FASEB J., 32, 2018
6NEU
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BU of 6neu by Molmil
FAD-dependent monooxygenase TropB from T. stipitatus R206Q variant
Descriptor: CHLORIDE ION, FAD-dependent monooxygenase tropB, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Rodriguez Benitez, A, Tweedy, S.E, Baker Dockrey, S.A, Lukowski, A.L, Wymore, T, Khare, D, Brooks, C.L, Palfey, B.A, Smith, J.L, Narayan, A.R.H.
Deposit date:2018-12-18
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
Acs Catalysis, 9, 2019
6NEV
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BU of 6nev by Molmil
FAD-dependent monooxygenase TropB from T. stipitatus Y239F Variant
Descriptor: CHLORIDE ION, FAD-dependent monooxygenase tropB, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Rodriguez Benitez, A, Tweedy, S.E, Baker Dockrey, S.A, Lukowski, A.L, Wymore, T, Khare, D, Palfey, B.A, Smith, J.L, Narayan, A.R.H.
Deposit date:2018-12-18
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
Acs Catalysis, 9, 2019
6NES
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BU of 6nes by Molmil
FAD-dependent monooxygenase TropB from T. stipitatus
Descriptor: CHLORIDE ION, FAD-dependent monooxygenase tropB, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Rodriguez Benitez, A, Tweedy, S.E, Baker Dockrey, S.A, Lukowski, A.L, Wymore, T, Khare, D, Brooks, C.L, Palfey, B.A, Smith, J.L, Narayan, A.R.H.
Deposit date:2018-12-18
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
Acs Catalysis, 9, 2019
6NET
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BU of 6net by Molmil
FAD-dependent monooxygenase TropB from T. stipitatus substrate complex
Descriptor: 2,4-dihydroxy-3,6-dimethylbenzaldehyde, CHLORIDE ION, FAD-dependent monooxygenase tropB, ...
Authors:Rodriguez Benitez, A, Tweedy, S.E, Baker Dockrey, S.A, Lukowski, A.L, Wymore, T, Khare, D, Brooks, C.L, Palfey, B.A, Smith, J.L, Narayan, A.R.H.
Deposit date:2018-12-18
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
Acs Catalysis, 9, 2019
6N04
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BU of 6n04 by Molmil
The X-ray crystal structure of AbsH3, an FAD dependent reductase from the Abyssomicin biosynthesis pathway in Streptomyces
Descriptor: AbsH3, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Clinger, J.A, Wang, X, Cai, W, Miller, M.D, Van Lanen, S.G, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2018-11-06
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:The crystal structure of AbsH3: A putative flavin adenine dinucleotide-dependent reductase in the abyssomicin biosynthesis pathway.
Proteins, 2020
5BUK
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BU of 5buk by Molmil
Structure of flavin-dependent chlorinase Mpy16
Descriptor: FADH2-dependent halogenase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL
Authors:Agarwal, V, Louie, G.V, Noel, J.P, Moore, B.S.
Deposit date:2015-06-03
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
6AIN
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BU of 6ain by Molmil
Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PnpA
Authors:Chen, Q.Z, Huang, Y, Duan, Y.J, Li, Z.K, Liu, W.D, Cui, Z.L.
Deposit date:2018-08-24
Release date:2018-10-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4: The key enzyme involved in p-nitrophenol degradation.
Biochem. Biophys. Res. Commun., 504, 2018
6AIO
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BU of 6aio by Molmil
Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4
Descriptor: PnpA
Authors:Chen, Q.Z, Huang, Y, Duan, Y.J, Li, Z.K, Liu, W.D, Cui, Z.L.
Deposit date:2018-08-24
Release date:2018-10-31
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Crystal structure of p-nitrophenol 4-monooxygenase PnpA from Pseudomonas putida DLL-E4: The key enzyme involved in p-nitrophenol degradation.
Biochem. Biophys. Res. Commun., 504, 2018
5BUL
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BU of 5bul by Molmil
Structure of flavin-dependent brominase Bmp2 triple mutant Y302S F306V A345W
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, flavin-dependent halogenase triple mutant
Authors:Agarwal, V, Louie, G.V, Noel, J.P, Moore, B.S.
Deposit date:2015-06-04
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9784 Å)
Cite:Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
2Y6Q
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BU of 2y6q by Molmil
Structure of the TetX monooxygenase in complex with the substrate 7- Iodtetracycline
Descriptor: 7-IODOTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ...
Authors:Volkers, G, Palm, G.J, Weiss, M.S, Wright, G.D, Hinrichs, W.
Deposit date:2011-01-25
Release date:2011-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural Basis for a New Tetracycline Resistance Mechanism Relying on the Tetx Monooxygenase.
FEBS Lett., 585, 2011

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