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2A6I
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Crystal structure analysis of the anti-arsonate germline antibody 36-65 in complex with a phage display derived dodecapeptide KLASIPTHTSPL
Descriptor: Dodecapeptide: KLASIPTHTSPL, Germline antibody 36-65 Fab heavy chain, Germline antibody 36-65 Fab light chain
Authors:Sethi, D.K, Agarwal, A, Manivel, V, Rao, K.V, Salunke, D.M.
Deposit date:2005-07-02
Release date:2006-06-13
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response.
Immunity, 24, 2006
4ORK
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BU of 4ork by Molmil
Crystal Structure of the Phosphotransferase Domain of the Bifunctional Aminoglycoside Resistance Enzyme AAC(6')-Ie-APH(2'')-Ia
Descriptor: Bifunctional AAC/APH, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Smith, C.A, Toth, M, Bhattacharya, M, Frase, H, Vakulenko, S.B.
Deposit date:2014-02-11
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the phosphotransferase domain of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia.
Acta Crystallogr.,Sect.D, 70, 2014
2YGM
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BU of 2ygm by Molmil
THE X-RAY CRYSTAL STRUCTURE OF TANDEM CBM51 MODULES OF SP3GH98, THE FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE SP3-BS71, IN COMPLEX WITH THE BLOOD GROUP B ANTIGEN
Descriptor: BLOOD GROUP A-AND B-CLEAVING ENDO-BETA-GALACTOSIDASE, CALCIUM ION, SODIUM ION, ...
Authors:Higgins, M.A, Ficko-Blean, E, Wright, C, Meloncelli, P.J, Lowary, T.L, Boraston, A.B.
Deposit date:2011-04-19
Release date:2011-06-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The Overall Architecture and Receptor Binding of Pneumococcal Carbohydrate Antigen Hydrolyzing Enzymes.
J.Mol.Biol., 411, 2011
1UN5
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ARH-II, AN ANGIOGENIN/RNASE A CHIMERA
Descriptor: ANGIOGENIN, CITRIC ACID
Authors:Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2003-09-04
Release date:2004-02-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic Studies on Structural Features that Determine the Enzymatic Specificity and Potency of Human Angiogenin: Thr44, Thr80 and Residues 38-41
Biochemistry, 43, 2004
4O6K
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BU of 4o6k by Molmil
The crystal structure of zebrafish IL-22
Descriptor: Interleukin 22
Authors:Siupka, P, Hamming, O.J, Fretaud, M, Luftalla, G, Levraud, J.P, Hartmann, R.
Deposit date:2013-12-21
Release date:2014-09-10
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of zebrafish IL-22 reveals an evolutionary, conserved structure highly similar to that of human IL-22.
Genes Immun., 15, 2014
2YNJ
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GroEL at sub-nanometer resolution by Constrained Single Particle Tomography
Descriptor: 60 KDA CHAPERONIN, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Bartesaghi, A, Lecumberry, F, Sapiro, G, Subramaniam, S.
Deposit date:2012-10-15
Release date:2012-12-12
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Protein Secondary Structure Determination by Constrained Single-Particle Cryo-Electron Tomography
Structure, 20, 2012
2P7S
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BU of 2p7s by Molmil
Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Amphinase-2, ...
Authors:Singh, U.P.
Deposit date:2007-03-20
Release date:2007-05-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes.
J.Mol.Biol., 371, 2007
2VWE
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Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment
Descriptor: ANTI-VEGF-B MONOCLONAL ANTIBODY, VASCULAR ENDOTHELIAL GROWTH FACTOR B
Authors:Leonard, P, Scotney, P.D, Jabeen, T, Iyer, S, Fabri, L.J, Nash, A.D, Acharya, K.R.
Deposit date:2008-06-23
Release date:2008-11-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment.
J.Mol.Biol., 384, 2008
2PKM
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Crystal structure of M tuberculosis Adenosine Kinase complexed with adenosine
Descriptor: ADENOSINE, Adenosine kinase
Authors:Reddy, M.C.M, Palaninathan, S.K, Shetty, N.D, Owen, J.L, Watson, M.D, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2007-04-17
Release date:2007-06-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme
J.Biol.Chem., 282, 2007
2PGE
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Crystal structure of MenC from Desulfotalea psychrophila LSv54
Descriptor: MenC
Authors:Agarwal, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-04-09
Release date:2007-04-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family.
Proc.Natl.Acad.Sci.USA, 111, 2014
1GWH
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BU of 1gwh by Molmil
Atomic resolution structure of Micrococcus Lysodeikticus catalase complexed with NADPH
Descriptor: ACETATE ION, Catalase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Murshudov, G.N, Grebenko, A.I, Brannigan, J.A, Antson, A.A, Barynin, V.V, Dodson, G.G, Dauter, Z, Wilson, K.S, Melik-Adamyan, W.R.
Deposit date:2002-03-15
Release date:2002-03-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Structures of Micrococcus Lysodeikticus Catalase, its Ferryl Intermediate (Compound II) and Nadph Complex.
Acta Crystallogr.,Sect.D, 58, 2002
2WK5
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BU of 2wk5 by Molmil
Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil
Descriptor: GLYCEROL, THYMIDINE PHOSPHORYLASE
Authors:Mitsiki, E, Papageorgiou, A.C, Iyer, S, Thiyagarajan, N, Prior, S.H, Sleep, D, Finnis, C, Acharya, K.R.
Deposit date:2009-06-05
Release date:2009-07-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil.
Biochem.Biophys.Res.Commun., 386, 2009
2X0K
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Crystal structure of modular FAD synthetase from Corynebacterium ammoniagenes
Descriptor: PYROPHOSPHATE, RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF, SULFATE ION
Authors:Herguedas, B, Hermoso, J.A, Martinez-Julvez, M, Medina, M, Frago, S.
Deposit date:2009-12-15
Release date:2010-05-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Oligomeric State in the Crystal Structure of Modular Fad Synthetase Provides Insights Into its Sequential Catalysis in Prokaryotes
J.Mol.Biol., 400, 2010
3C9J
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BU of 3c9j by Molmil
The Crystal structure of Transmembrane domain of M2 protein and Amantadine complex
Descriptor: (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, Proton Channel protein M2, transmembrane segment
Authors:Stouffer, A.L, Acharya, R, Salom, D.
Deposit date:2008-02-15
Release date:2008-03-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for the function and inhibition of an influenza virus proton channel
Nature, 451, 2008
1HK1
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HUMAN SERUM ALBUMIN COMPLEXED WITH THYROXINE (3,3',5,5'-TETRAIODO-L-THYRONINE)
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, SERUM ALBUMIN
Authors:Petitpas, I, Petersen, C.E, Ha, C.E, Bhattacharya, A.A, Zunszain, P.A, Ghuman, J, Bhagavan, N.V, Curry, S.
Deposit date:2003-03-05
Release date:2003-05-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis of Albumin-Thyroxine Interactions and Familial Dysalbuminemic Hyperthyroxinemia
Proc.Natl.Acad.Sci.USA, 100, 2003
1HK3
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Human serum albumin mutant r218p complexed with thyroxine (3,3',5,5'-tetraiodo-l-thyronine)
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, SERUM ALBUMIN
Authors:Petitpas, I, Petersen, C.E, Ha, C.E, Bhattacharya, A.A, Zunszain, P.A, Ghuman, J, Bhagavan, N.V, Curry, S.
Deposit date:2003-03-05
Release date:2003-05-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Albumin-Thyroxine Interactions and Familial Dysalbuminemic Hyperthyroxinemia
Proc.Natl.Acad.Sci.USA, 100, 2003
1HK2
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HUMAN SERUM ALBUMIN MUTANT R218H COMPLEXED WITH THYROXINE (3,3',5,5'-TETRAIODO-L-THYRONINE)
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, SERUM ALBUMIN
Authors:Petitpas, I, Petersen, C.E, Ha, C.E, Bhattacharya, A.A, Zunszain, P.A, Ghuman, J, Bhagavan, N.V, Curry, S.
Deposit date:2003-03-05
Release date:2003-05-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of Albumin-Thyroxine Interactions and Familial Dysalbuminemic Hyperthyroxinemia
Proc.Natl.Acad.Sci.USA, 100, 2003
1B0A
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BU of 1b0a by Molmil
5,10, METHYLENE-TETRAHYDROPHOLATE DEHYDROGENASE/CYCLOHYDROLASE FROM E COLI.
Descriptor: PROTEIN (FOLD BIFUNCTIONAL PROTEIN)
Authors:Shen, B.W, Dyer, D, Huang, J.-Y, D'Ari, L, Rabinowitz, J, Stoddard, B.L.
Deposit date:1998-11-06
Release date:1999-06-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:The crystal structure of a bacterial, bifunctional 5,10 methylene-tetrahydrofolate dehydrogenase/cyclohydrolase.
Protein Sci., 8, 1999
2X90
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BU of 2x90 by Molmil
Crystal structure of AnCE-enalaprilat complex
Descriptor: 1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R.
Deposit date:2010-03-14
Release date:2010-06-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.
J.Mol.Biol., 400, 2010
2OXK
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Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers: GCN4-pLI with beta-residues at b and f heptad positions.
Descriptor: FORMIC ACID, hybrid alpha/beta peptide based on the GCN4-pLI sequence; heptad positions b and f substituted with beta-amino acids
Authors:Horne, W.S, Price, J.L, Keck, J.L, Gellman, S.H.
Deposit date:2007-02-20
Release date:2007-03-27
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Helix Bundle Quaternary Structure from alpha/beta-Peptide Foldamers.
J.Am.Chem.Soc., 129, 2007
2X8Z
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Crystal structure of AnCE-captopril complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN CONVERTING ENZYME, L-CAPTOPRIL, ...
Authors:Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R.
Deposit date:2010-03-14
Release date:2010-06-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.
J.Mol.Biol., 400, 2010
2X94
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Crystal structure of AnCE-perindoprilat complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ANGIOTENSIN CONVERTING ENZYME, ...
Authors:Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R.
Deposit date:2010-03-14
Release date:2010-06-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.
J.Mol.Biol., 400, 2010
1GZ6
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(3R)-HYDROXYACYL-COA DEHYDROGENASE FRAGMENT OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ESTRADIOL 17 BETA-DEHYDROGENASE 4, SULFATE ION
Authors:Haapalainen, A.M, Hiltunen, J.K, Glumoff, T.
Deposit date:2002-05-16
Release date:2003-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Binary Structure of the Two-Domain (3R)-Hydroxyacyl-Coa Dehydrogenase from Rat Peroxisomal Multifunctional Enzyme Type 2 at 2.38 A Resolution
Structure, 11, 2003
2X91
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Crystal structure of AnCE-lisinopril complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ANGIOTENSIN CONVERTING ENZYME, ...
Authors:Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R.
Deposit date:2010-03-14
Release date:2010-06-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.
J.Mol.Biol., 400, 2010
1W4O
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Binding of Nonnatural 3'-Nucleotides to Ribonuclease A
Descriptor: PANCREATIC RIBONUCLEASE A, URACIL ARABINOSE-3'-PHOSPHATE
Authors:Jenkins, C.L, Thiyagarajan, N, Sweeney, R.Y, Guy, M.P, Kelemen, B.R, Acharya, K.R, Raines, R.T.
Deposit date:2004-07-27
Release date:2005-02-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Binding of Non-Natural 3'-Nucleotides to Ribonuclease A
FEBS J., 272, 2005

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