3C9J

The Crystal structure of Transmembrane domain of M2 protein and Amantadine complex

Summary for 3C9J

Entry DOI	10.2210/pdb3c9j/pdb
Descriptor	Proton Channel protein M2, transmembrane segment, (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine (2 entities in total)
Functional Keywords	proton channel, ion channel, m2tm, m2-amantadine complex, membrane protein
Cellular location	Virion membrane (By similarity): O70632
Total number of polymer chains	4
Total formula weight	11128.53
Authors	Stouffer, A.L.,Acharya, R.,Salom, D. (deposition date: 2008-02-15, release date: 2008-03-11, Last modification date: 2024-04-03)
Primary citation	Stouffer, A.L.,Acharya, R.,Salom, D.,Levine, A.S.,Costanzo, L.D.,Soto, C.S.,Tereshko, V.,Nanda, V.,Stayrook, S.,DeGrado, W.F. Structural basis for the function and inhibition of an influenza virus proton channel Nature, 451:596-600, 2008 Cited by PubMed: 18235504 DOI: 10.1038/nature06528 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation