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6JJO
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BU of 6jjo by Molmil
Crystal structure of the DegP dodecamer with a modulator
Descriptor: Periplasmic serine endoprotease DegP, TMB-CYRKL modulator
Authors:Cho, H, Choi, Y, Lee, H.H, Kim, S.
Deposit date:2019-02-26
Release date:2020-09-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.157 Å)
Cite:Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy
Commun Biol, 3, 2020
3STJ
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BU of 3stj by Molmil
Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli
Descriptor: Protease degQ, peptide (UNK)
Authors:Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
Deposit date:2011-07-11
Release date:2011-07-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
3SHW
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BU of 3shw by Molmil
Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide
Descriptor: Gap junction gamma-1 protein, Tight junction protein ZO-1
Authors:Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M.
Deposit date:2011-06-17
Release date:2011-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
3TMH
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BU of 3tmh by Molmil
Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent protein kinase A type II alpha and PDZK1
Descriptor: A-kinase anchor protein 10, mitochondrial, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, ...
Authors:Sarma, G.N, Phan, R.H, Sankaran, B, Taylor, S.S.
Deposit date:2011-08-31
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Differential mode of D-AKAP2 to PKA isoforms: Insights from D-AKAP2 PKA RII PDZK1 ternary complex structure
To be Published
3SUZ
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BU of 3suz by Molmil
Crystal structure of Rat Mint2 PPC
Descriptor: Amyloid beta A4 precursor protein-binding family A member 2
Authors:Shen, Y, Long, J, Yan, X, Xie, X.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Open-closed motion of Mint2 regulates APP metabolism
J Mol Cell Biol, 5, 2013
3TSW
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BU of 3tsw by Molmil
crystal structure of the PDZ3-SH3-GUK core module of Human ZO-1
Descriptor: SULFATE ION, Tight junction protein ZO-1
Authors:Nomme, J, Lavie, A.
Deposit date:2011-09-13
Release date:2011-10-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.847 Å)
Cite:The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1.
J.Biol.Chem., 286, 2011
1Z87
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BU of 1z87 by Molmil
solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
Descriptor: Alpha-1-syntrophin
Authors:Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M.
Deposit date:2005-03-30
Release date:2006-01-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
6SAK
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BU of 6sak by Molmil
Structure of the OTULINcat C129A - SNX27 PDZ domain complex.
Descriptor: GLYCEROL, SULFATE ION, Sorting nexin-27, ...
Authors:Elliott, P.R, Komander, D.
Deposit date:2019-07-17
Release date:2019-10-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Regulation of the endosomal SNX27-retromer by OTULIN.
Nat Commun, 10, 2019
1KY9
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BU of 1ky9 by Molmil
Crystal Structure of DegP (HtrA)
Descriptor: PROTEASE DO
Authors:Krojer, T, Garrido-Franco, M, Huber, R, Ehrmann, M, Clausen, T.
Deposit date:2002-02-04
Release date:2002-04-03
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine.
Nature, 416, 2002
3MH4
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BU of 3mh4 by Molmil
HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues
Descriptor: Protease do
Authors:Krojer, T, Sawa, J, Huber, R, Clausen, T.
Deposit date:2010-04-07
Release date:2010-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
3MH5
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BU of 3mh5 by Molmil
HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues
Descriptor: DIISOPROPYL PHOSPHONATE, Protease do
Authors:Krojer, T, Sawa, J, Huber, R, Clausen, T.
Deposit date:2010-04-07
Release date:2010-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
3MH6
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BU of 3mh6 by Molmil
HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues
Descriptor: DIISOPROPYL PHOSPHONATE, Protease do
Authors:Krojer, T, Sawa, J, Huber, R, Clausen, T.
Deposit date:2010-04-07
Release date:2010-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
3MH7
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BU of 3mh7 by Molmil
HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues
Descriptor: 5-mer peptide, Protease do
Authors:Krojer, T, Sawa, J, Huber, R, Clausen, T.
Deposit date:2010-04-07
Release date:2010-06-30
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2.961 Å)
Cite:HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
1P1D
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BU of 1p1d by Molmil
Structural Insights into the Inter-domain Chaperoning of Tandem PDZ Domains in Glutamate Receptor Interacting Proteins
Descriptor: Glutamate receptor interacting protein
Authors:Feng, W, Shi, Y, Li, M, Zhang, M.
Deposit date:2003-04-12
Release date:2003-11-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding
Nat.Struct.Biol., 10, 2003
3CS0
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BU of 3cs0 by Molmil
Crystal structure of DegP24
Descriptor: Periplasmic serine endoprotease DegP, pentapeptide
Authors:Krojer, T, Sawa, J, Schaefer, E, Saibil, H.R, Ehrmann, M, Clausen, T.
Deposit date:2008-04-08
Release date:2008-05-27
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
5E6P
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BU of 5e6p by Molmil
PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex
Descriptor: Plexin-B2, Rho guanine nucleotide exchange factor 11
Authors:Pascoe, H.G, Zhang, X.
Deposit date:2015-10-10
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.215 Å)
Cite:Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Proc.Natl.Acad.Sci.USA, 112, 2015
3OU0
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BU of 3ou0 by Molmil
re-refined 3CS0
Descriptor: Periplasmic serine endoprotease DegP, heptapeptide, pentapeptide
Authors:Sauer, R.T, Grant, R.A, Kim, S.
Deposit date:2010-09-14
Release date:2011-01-19
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages.
Cell(Cambridge,Mass.), 145, 2011
4L8N
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BU of 4l8n by Molmil
Crystal structure of a PDZ domain protein (BDI_1242) from Parabacteroides distasonis ATCC 8503 at 2.50 A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ETHANOL, MAGNESIUM ION, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2013-06-17
Release date:2013-06-26
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a PDZ domain protein (BDI_1242) from Parabacteroides distasonis ATCC 8503 at 2.50 A resolution
To be published
4P2A
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BU of 4p2a by Molmil
Structure of mouse VPS26A bound to rat SNX27 PDZ domain
Descriptor: MERCURY (II) ION, Sorting nexin-27, Vacuolar protein sorting-associated protein 26A
Authors:Clairfeuille, T, Gallon, M, Mas, C, Ghai, R, Teasdale, R, Cullen, P, Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Proc.Natl.Acad.Sci.USA, 111, 2014
2KRG
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BU of 2krg by Molmil
Solution Structure of human sodium/ hydrogen exchange regulatory factor 1(150-358)
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S, Dai, Z, Li, J, Baxter, S, Callaway, D.J.E, Cowburn, D, Bu, Z.
Deposit date:2009-12-17
Release date:2009-12-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation.
J.Biol.Chem., 285, 2010
1SOT
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BU of 1sot by Molmil
Crystal Structure of the DegS stress sensor
Descriptor: Protease degS
Authors:Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
Deposit date:2004-03-15
Release date:2004-06-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
1SOZ
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BU of 1soz by Molmil
Crystal Structure of DegS protease in complex with an activating peptide
Descriptor: Protease degS, activating peptide
Authors:Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
Deposit date:2004-03-16
Release date:2004-06-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
8T1J
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BU of 8t1j by Molmil
Uncrosslinked nNOS-CaM oxygenase homodimer
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric oxide synthase 1, ...
Authors:Lee, K, Pospiech, T.H, Southworth, D.
Deposit date:2023-06-02
Release date:2023-11-29
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry.
J.Biol.Chem., 300, 2023
8T1K
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BU of 8t1k by Molmil
DSBU crosslinked nNOS-CaM oxygenase homodimer
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric oxide synthase 1, ...
Authors:Lee, K, Pospiech, T.H, Southworth, D.
Deposit date:2023-06-02
Release date:2023-11-29
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry.
J.Biol.Chem., 300, 2023
6EW9
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BU of 6ew9 by Molmil
CRYSTAL STRUCTURE OF DEGS STRESS SENSOR PROTEASE IN COMPLEX WITH ACTIVATING DNRLGLVYQF PEPTIDE
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNRLGLVYQF PEPTIDE, ...
Authors:Vetter, I.R, Porfetye, A.T, Stege, P.
Deposit date:2017-11-03
Release date:2018-04-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes.
ACS Chem. Biol., 13, 2018

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