PDB: 871 resultsInfo pagesStatus searchChemie searchBIRD

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8FEF	Structure of Mce1 transporter from Mycobacterium smegmatis (Map0) Descriptor: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... Authors: Chen, J, Bhabha, G, Ekiert, D.C. Deposit date: 2022-12-06 Release date: 2023-02-22 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (2.71 Å) Cite: Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
8FED	Structure of Mce1-LucB complex from Mycobacterium smegmatis (Map1) Descriptor: ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... Authors: Chen, J, Bhabha, G, Ekiert, D.C. Deposit date: 2022-12-06 Release date: 2023-02-22 Last modified: 2023-08-23 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: Structure of an endogenous mycobacterial MCE lipid transporter. Nature, 620, 2023
7F02	Cytochrome c-type biogenesis protein CcmABCD from E. coli Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... Authors: Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. Deposit date: 2021-06-03 Release date: 2022-11-09 Method: ELECTRON MICROSCOPY (3.24 Å) Cite: Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
8F4B	Bovine multidrug resistance protein 1 (MRP1) bound to cyclic peptide inhibitor 1 (CPI1) Descriptor: Cyclic peptide inhibitor 1 (CPI1), Multidrug resistance-associated protein 1 Authors: Pietz, H.L, Chen, J. Deposit date: 2022-11-10 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (3.27 Å) Cite: A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation. Proc.Natl.Acad.Sci.USA, 120, 2023
8F5B	Human ABCA4 structure in complex with AMP-PNP Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Scortecci, J.F, Van Petegem, F, Molday, R.S. Deposit date: 2022-11-13 Release date: 2023-11-22 Method: ELECTRON MICROSCOPY (3.95 Å) Cite: Structural and Functional Characterization of ABCA4 in its Nucleotide-Bound State To Be Published
7FC9	Crystal structure of CmABCB1 in lipidic mesophase revealed by LCP-SFX Descriptor: ACETATE ION, CHLORIDE ION, MAGNESIUM ION, ... Authors: Pan, D, Oyama, R, Sato, T, Nakane, T, Mizunuma, R, Matsuoka, K, Joti, Y, Tono, K, Nango, E, Iwata, S, Nakatsu, T, Kato, H. Deposit date: 2021-07-14 Release date: 2022-02-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX. Iucrj, 9, 2022
8G4C	BceABS ATPgS high res TM Descriptor: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: George, N.L, Orlando, B.J. Deposit date: 2023-02-09 Release date: 2023-06-21 Last modified: 2023-07-12 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
8G3B	BceAB-S nucleotide free TM state 2 Descriptor: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... Authors: George, N.L, Orlando, B.J. Deposit date: 2023-02-07 Release date: 2023-06-21 Last modified: 2023-07-12 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
8G3F	BceAB-S nucleotide free BceS state 1 Descriptor: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... Authors: George, N.L, Orlando, B.J. Deposit date: 2023-02-07 Release date: 2023-06-21 Last modified: 2023-07-12 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
8G3L	BceAB-S nucleotide free BceS state 2 Descriptor: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... Authors: George, N.L, Orlando, B.J. Deposit date: 2023-02-08 Release date: 2023-06-21 Last modified: 2023-07-12 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
8G3A	BceAB-S nucleotide free TM state 1 Descriptor: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... Authors: George, N.L, Orlando, B.J. Deposit date: 2023-02-07 Release date: 2023-06-21 Last modified: 2023-07-12 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
8G4D	BceABS ATPgS tilted BceS Descriptor: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: George, N.L, Orlando, B.J. Deposit date: 2023-02-09 Release date: 2023-06-21 Last modified: 2023-07-12 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
7FDV	Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family G member 1, CHOLESTEROL, ... Authors: Xu, D, Li, Y.Y, Yang, F.R, Sun, C.R, Pan, J.H, Wang, L, Chen, Z.P, Fang, S.C, Yao, X.B, Hou, W.T, Zhou, C.Z, Chen, Y. Deposit date: 2021-07-18 Release date: 2022-06-22 Last modified: 2022-06-29 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Structure and transport mechanism of the human cholesterol transporter ABCG1. Cell Rep, 38, 2022
7F04	Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with Heme and ATP. Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, Cytochrome c biogenesis ATP-binding export protein CcmA, ... Authors: Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. Deposit date: 2021-06-03 Release date: 2022-11-09 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
7F03	Cytochrome c-type biogenesis protein CcmABCD from E. coli in complex with ANP Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, ... Authors: Li, J, Zheng, W, Gu, M, Zhang, K, Zhu, J.P. Deposit date: 2021-06-03 Release date: 2022-11-09 Method: ELECTRON MICROSCOPY (3.29 Å) Cite: Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
8JY5	Cryo-EM structure of human ABC transporter ABCC2 in apo" state Descriptor: ATP-binding cassette sub-family C member 2 Authors: Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. Deposit date: 2023-07-03 Release date: 2024-01-03 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (4.17 Å) Cite: Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
8JY4	Cryo-EM structure of human ABC transporter ABCC2 in apo' state Descriptor: ATP-binding cassette sub-family C member 2 Authors: Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. Deposit date: 2023-07-02 Release date: 2024-01-03 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
8Y6I	P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in nanodisc Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, ATP-dependent translocase ABCB1,mNeonGreen, CHOLESTEROL, ... Authors: Hamaguchi-Suzuki, N, Adachi, N, Moriya, T, Kawasaki, M, Suzuki, K, Anzai, N, Senda, T, Murata, T. Deposit date: 2024-02-02 Release date: 2024-04-17 Method: ELECTRON MICROSCOPY (2.54 Å) Cite: Cryo-EM structure of P-glycoprotein bound to triple elacridar inhibitor molecules. Biochem.Biophys.Res.Commun., 709, 2024
8JX7	Cryo-EM structure of human ABC transporter ABCC2 Descriptor: ATP-binding cassette sub-family C member 2 Authors: Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. Deposit date: 2023-06-30 Release date: 2024-01-03 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
8JXU	Cryo-EM structure of human ABC transporter ABCC2 under active turnover condition Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 2, ... Authors: Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. Deposit date: 2023-07-01 Release date: 2024-01-03 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.55 Å) Cite: Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
8J3W	Cryo-EM structure of aspirin-bound ABCC4 Descriptor: 2-(ACETYLOXY)BENZOIC ACID, ATP-binding cassette sub-family C member 4 Authors: Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. Deposit date: 2023-04-18 Release date: 2023-05-24 Method: ELECTRON MICROSCOPY (3.07 Å) Cite: Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
8J3Z	Cryo-EM structure of ATP-U46619-bound ABCC4 Descriptor: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, ... Authors: Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. Deposit date: 2023-04-18 Release date: 2023-05-24 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
8SZC	Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to substrate and ATP: BmrCD_IF-1HT/ATP Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Tang, Q, Mchaourab, H. Deposit date: 2023-05-29 Release date: 2023-11-15 Last modified: 2023-11-22 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter. Nat Commun, 14, 2023
8Y6H	P-glycoprotein in complex with UIC2 Fab and triple elacridar molecules in LMNG detergent Descriptor: ATP-dependent translocase ABCB1,mNeonGreen, UIC2 Fab heavy chain, UIC2 Fab light chain, ... Authors: Hamaguchi-Suzuki, N, Adachi, N, Moriya, T, Kawasaki, M, Suzuki, K, Anzai, N, Senda, T, Murata, T. Deposit date: 2024-02-02 Release date: 2024-04-17 Method: ELECTRON MICROSCOPY (2.49 Å) Cite: Cryo-EM structure of P-glycoprotein bound to triple elacridar inhibitor molecules. Biochem.Biophys.Res.Commun., 709, 2024
8JWG	Cryo-EM structure of Plasmodium falciparum multidrug resistance protein 1 without H1 helix in complex with MFQ Descriptor: Mefloquine, Multidrug resistance protein 1 Authors: Li, M, Si, K. Deposit date: 2023-06-29 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: The structure of Plasmodium falciparum multidrug resistance protein 1 reveals an N-terminal regulatory domain. Proc.Natl.Acad.Sci.USA, 120, 2023

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