6NFC
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![BU of 6nfc by Molmil](/molmil-images/mine/6nfc) | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP42 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP42 fragment antigen binding heavy chain, ... | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | Deposit date: | 2018-12-19 | Release date: | 2019-11-06 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science, 366, 2019
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6NBP
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![BU of 6nbp by Molmil](/molmil-images/mine/6nbp) | Crystal Structure of a Sugar N-Formyltransferase from the Plant Pathogen Pantoea ananatis | Descriptor: | N-formyltransferase, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid, PHOSPHATE ION, ... | Authors: | Hofmeister, D.L, Thoden, J.B, Holden, H.M. | Deposit date: | 2018-12-09 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Investigation of a sugar N-formyltransferase from the plant pathogen Pantoea ananatis. Protein Sci., 28, 2019
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6QBF
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![BU of 6qbf by Molmil](/molmil-images/mine/6qbf) | Crystal structure of the pathological D187N variant of calcium-free human gelsolin. | Descriptor: | GLYCEROL, Gelsolin, SODIUM ION, ... | Authors: | Scalone, E, Boni, F, Milani, M, Eloise, M, de Rosa, M. | Deposit date: | 2018-12-21 | Release date: | 2019-11-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.499 Å) | Cite: | The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties. Eur.Biophys.J., 49, 2020
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4Y5L
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![BU of 4y5l by Molmil](/molmil-images/mine/4y5l) | Endothiapepsin in its apo form | Descriptor: | ACETATE ION, DI(HYDROXYETHYL)ETHER, Endothiapepsin, ... | Authors: | Schiebel, J, Heine, A, Klebe, G. | Deposit date: | 2015-02-11 | Release date: | 2016-03-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (0.99 Å) | Cite: | Crystallographic Fragment Screening of an Entire Library To Be Published
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3R2K
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![BU of 3r2k by Molmil](/molmil-images/mine/3r2k) | 1.55A resolution structure of As-Isolated FtnA from Pseudomonas aeruginosa (pH 7.5) | Descriptor: | Bacterioferritin, SODIUM ION | Authors: | Lovell, S.W, Battaile, K.P, Yao, H, Jepkorir, G, Nama, P.V, Weeratunga, S, Rivera, M. | Deposit date: | 2011-03-14 | Release date: | 2011-05-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Two distinct ferritin-like molecules in Pseudomonas aeruginosa: the product of the bfrA gene is a bacterial ferritin (FtnA) and not a bacterioferritin (Bfr). Biochemistry, 50, 2011
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6PVD
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![BU of 6pvd by Molmil](/molmil-images/mine/6pvd) | |
6Q0M
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![BU of 6q0m by Molmil](/molmil-images/mine/6q0m) | Structure of Erbin PDZ derivative E-14 with a high-affinity peptide | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2019-08-02 | Release date: | 2019-11-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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6NC9
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![BU of 6nc9 by Molmil](/molmil-images/mine/6nc9) | Lipid II flippase MurJ, outward-facing conformation | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Lipid II flippase MurJ, ... | Authors: | Kuk, A.C.Y, Lee, S.-Y. | Deposit date: | 2018-12-11 | Release date: | 2019-04-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Visualizing conformation transitions of the Lipid II flippase MurJ. Nat Commun, 10, 2019
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6NOK
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![BU of 6nok by Molmil](/molmil-images/mine/6nok) | The X-ray crystal structure of Streptococcus pneumoniae Fatty Acid Kinase (Fak) B1 protein loaded with myristic acid (C14:0) to 1.69 Angstrom resolution | Descriptor: | Fatty Acid Kinase (Fak) B1 protein, MYRISTIC ACID, SODIUM ION | Authors: | Cuypers, M.G, Gullett, J.M, Subramanian, C, White, S.W, Rock, C.O. | Deposit date: | 2019-01-16 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | The X-ray crystal structure of Streptococcus pneumoniae Fatty Acid Kinase (Fak) B1 protein loaded with myristic acid (C14:0) to 1.69 Angstrom resolution To Be Published
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6PUN
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![BU of 6pun by Molmil](/molmil-images/mine/6pun) | Crystal structure of a ternary complex of FBF-2 with LST-1 (site B) and compact FBE RNA | Descriptor: | 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, GLYCEROL, ... | Authors: | Qiu, C, Campbell, Z.T, Hall, T.M.T. | Deposit date: | 2019-07-18 | Release date: | 2019-08-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity. Elife, 8, 2019
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6N6A
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![BU of 6n6a by Molmil](/molmil-images/mine/6n6a) | Vibrio cholerae Oligoribonuclease bound to pGG | Descriptor: | Oligoribonuclease, RNA (5'-R(P*GP*G)-3'), SODIUM ION | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2018-11-26 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation. Elife, 8, 2019
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6N6G
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![BU of 6n6g by Molmil](/molmil-images/mine/6n6g) | Vibrio cholerae Oligoribonuclease bound to pCG | Descriptor: | Oligoribonuclease, RNA (5'-R(P*CP*G)-3'), SODIUM ION | Authors: | Lormand, J.D, Sondermann, H. | Deposit date: | 2018-11-26 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.018 Å) | Cite: | A dedicated diribonucleotidase resolves a key bottleneck for the terminal step of RNA degradation. Elife, 8, 2019
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4YPO
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![BU of 4ypo by Molmil](/molmil-images/mine/4ypo) | |
6PZT
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![BU of 6pzt by Molmil](/molmil-images/mine/6pzt) | cryo-EM structure of human NKCC1 | Descriptor: | Solute carrier family 12 member 2 | Authors: | Cao, E, Wang, Q, Yang, X. | Deposit date: | 2019-08-01 | Release date: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy. Nat Commun, 11, 2020
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4YT9
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![BU of 4yt9 by Molmil](/molmil-images/mine/4yt9) | Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) substrate-unbound. | Descriptor: | GLYCEROL, Peptidylarginine deiminase, SODIUM ION | Authors: | Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X. | Deposit date: | 2015-03-17 | Release date: | 2015-07-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase. Sci Rep, 5, 2015
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4YD1
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![BU of 4yd1 by Molmil](/molmil-images/mine/4yd1) | Ternary complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate and an incoming nonhydrolyzable dUMPNPP | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ... | Authors: | Moon, A.F, Gosavi, R.A, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | Deposit date: | 2015-02-20 | Release date: | 2015-08-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Creative template-dependent synthesis by human polymerase mu. Proc.Natl.Acad.Sci.USA, 112, 2015
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6NAF
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![BU of 6naf by Molmil](/molmil-images/mine/6naf) | De novo designed homo-trimeric amantadine-binding protein | Descriptor: | (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, SODIUM ION, amantadine-binding protein | Authors: | Selvaraj, B, Park, J, Cuneo, M.J, Myles, D.A.A, Baker, D. | Deposit date: | 2018-12-05 | Release date: | 2019-12-18 | Last modified: | 2023-10-25 | Method: | NEUTRON DIFFRACTION (1.923 Å), X-RAY DIFFRACTION | Cite: | De novo design of a homo-trimeric amantadine-binding protein. Elife, 8, 2019
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6NKT
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![BU of 6nkt by Molmil](/molmil-images/mine/6nkt) | |
4YOP
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![BU of 4yop by Molmil](/molmil-images/mine/4yop) | CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION | Authors: | Sugahara, M, Nakane, T, Suzuki, M, Nango, E. | Deposit date: | 2015-03-12 | Release date: | 2015-12-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Native sulfur/chlorine SAD phasing for serial femtosecond crystallography Acta Crystallogr.,Sect.D, 71, 2015
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6Q11
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![BU of 6q11 by Molmil](/molmil-images/mine/6q11) | Crystal structure of MurA from Clostridium difficile, mutation C116S, in the presence of URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID | Descriptor: | 1,2-ETHANEDIOL, SODIUM ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, ... | Authors: | Dopkins, B.J, Call, C.J, Thoden, J.B, Holden, H.M. | Deposit date: | 2019-08-02 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of MurA from Clostridium difficile, mutation C116S, in the presence of URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID To Be Published
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4YWD
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![BU of 4ywd by Molmil](/molmil-images/mine/4ywd) | Structure of rat cytosolic pepck in complex with 2,3-Pyridine dicarboxylic acid | Descriptor: | MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... | Authors: | Balan, M.D, Johnson, T.A, Mcleod, M.J, Lotosky, W.R, Holyoak, T. | Deposit date: | 2015-03-20 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
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4YHQ
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![BU of 4yhq by Molmil](/molmil-images/mine/4yhq) | Crystal structure of multidrug resistant clinical isolate PR20 with GRL-5010A | Descriptor: | (3R,3aS,6aS)-4,4-difluorohexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, CHLORIDE ION, GLYCEROL, ... | Authors: | Agniswamy, J, Weber, I.T. | Deposit date: | 2015-02-27 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20. J.Med.Chem., 58, 2015
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6QF2
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![BU of 6qf2 by Molmil](/molmil-images/mine/6qf2) | X-Ray structure of Thermolysin crystallized on a silicon chip | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, ... | Authors: | Lieske, J, Cerv, M, Kreida, S, Barthelmess, M, Fischer, P, Pakendorf, T, Yefanov, O, Mariani, V, Seine, T, Ross, B.H, Crosas, E, Lorbeer, O, Burkhardt, A, Lane, T.J, Guenther, S, Bergtholdt, J, Schoen, S, Tornroth-Horsefield, S, Chapman, H.N, Meents, A. | Deposit date: | 2019-01-09 | Release date: | 2019-07-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.733 Å) | Cite: | On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies. Iucrj, 6, 2019
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6MXS
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![BU of 6mxs by Molmil](/molmil-images/mine/6mxs) | Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98F,HC-G99M] | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... | Authors: | Shi, R, Picard, M.-E, Manenda, M.S. | Deposit date: | 2018-10-31 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Binding symmetry and surface flexibility mediate antibody self-association. Mabs, 11, 2019
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4YUC
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![BU of 4yuc by Molmil](/molmil-images/mine/4yuc) | Crystal Structure of CorB derivatized with S-(2-acetamidoethyl) 4-methyl-3-oxohexanethioate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CorB, SODIUM ION | Authors: | Zocher, G, Vilstrup, J, Stehle, T. | Deposit date: | 2015-03-18 | Release date: | 2016-03-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Structural basis of head to head polyketide fusion by CorB. Chem Sci, 6, 2015
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