1TDU
| E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH CB3717 AND 2'-DEOXYURIDINE (DURD) | Descriptor: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE, PHOSPHATE ION, ... | Authors: | Stout, T.J, Sage, C.R, Stroud, R.M. | Deposit date: | 1997-06-25 | Release date: | 1998-07-01 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The additivity of substrate fragments in enzyme-ligand binding. Structure, 6, 1998
|
|
1TDA
| STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE | Descriptor: | PHOSPHATE ION, THYMIDYLATE SYNTHASE | Authors: | Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M. | Deposit date: | 1993-02-15 | Release date: | 1993-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate. Biochemistry, 32, 1993
|
|
4MHD
| Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with spermidine | Descriptor: | SPERMIDINE, Spermidine n1-acetyltransferase | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Kuhn, M.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-29 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure. J.Mol.Biol., 427, 2015
|
|
3VVL
| Crystal structure of L-serine-O-acetyltransferase found in D-cycloserine biosynthetic pathway | Descriptor: | Homoserine O-acetyltransferase | Authors: | Oda, K, Matoba, Y, Kumagai, T, Noda, M, Sugiyama, M. | Deposit date: | 2012-07-26 | Release date: | 2013-03-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystallographic study to determine the substrate specificity of an L-serine-acetylating enzyme found in the D-cycloserine biosynthetic pathway J.Bacteriol., 195, 2013
|
|
1TDC
| STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | Authors: | Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M. | Deposit date: | 1993-02-15 | Release date: | 1993-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate. Biochemistry, 32, 1993
|
|
1EVF
| CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI | Descriptor: | SULFATE ION, THYMIDYLATE SYNTHASE | Authors: | Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L. | Deposit date: | 2000-04-19 | Release date: | 2000-05-03 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry, 39, 2000
|
|
1THY
| |
1TIS
| |
3W01
| Crystal structure of PcrB complexed with PEG from Staphylococcus aureus subsp. aureus Mu3 | Descriptor: | Heptaprenylglyceryl phosphate synthase, TRIETHYLENE GLYCOL | Authors: | Ren, F, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Chan, H.C, Liu, Y.L, Wang, K, Chen, C.C, Pang, X, He, M, Li, Y, Oldfield, E, Guo, R.T. | Deposit date: | 2012-10-17 | Release date: | 2012-12-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus Chembiochem, 14, 2013
|
|
3VX8
| |
1JP3
| Structure of E.coli undecaprenyl pyrophosphate synthase | Descriptor: | 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, undecaprenyl pyrophosphate synthase | Authors: | Ko, T.P, Chen, Y.K, Robinson, H, Tsai, P.C, Gao, Y.G, Chen, A.P.C, Wang, A.H.J, Liang, P.H. | Deposit date: | 2001-07-31 | Release date: | 2001-08-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis. J.Biol.Chem., 276, 2001
|
|
1JMF
| |
5XNH
| Crystal structure of the branched-chain polyamine synthase (BpsA) in complex with spermidine | Descriptor: | FE (III) ION, N(4)-bis(aminopropyl)spermidine synthase, SPERMIDINE | Authors: | Mizohata, E, Tse, K.M, Fujita, J, Inoue, T. | Deposit date: | 2017-05-22 | Release date: | 2017-10-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile-specific branched-chain polyamine. FEBS J., 284, 2017
|
|
2D51
| Pentaketide chromone synthase (M207G mutant) | Descriptor: | pentaketide chromone synthase | Authors: | Kohno, T, Morita, H. | Deposit date: | 2005-10-27 | Release date: | 2006-11-14 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Insight into Chain-Length Control and Product Specificity of Pentaketide Chromone Synthase from Aloe arborescens Chem.Biol., 14, 2007
|
|
5XOQ
| |
5XA2
| |
1PLA
| HIGH-RESOLUTION SOLUTION STRUCTURE OF REDUCED PARSLEY PLASTOCYANIN | Descriptor: | COPPER (II) ION, PLASTOCYANIN | Authors: | Bagby, S, Driscoll, P.C, Harvey, T.S, Hill, H.A.O. | Deposit date: | 1994-05-20 | Release date: | 1994-08-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | High-resolution solution structure of reduced parsley plastocyanin. Biochemistry, 33, 1994
|
|
2ZCR
| Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-698 | Descriptor: | Dehydrosqualene synthase, MAGNESIUM ION, tripotassium (1R)-4-(4'-butylbiphenyl-4-yl)-1-phosphonatobutane-1-sulfonate | Authors: | Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. | Deposit date: | 2007-11-11 | Release date: | 2008-03-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008
|
|
1EYS
| CRYSTAL STRUCTURE OF PHOTOSYNTHETIC REACTION CENTER FROM A THERMOPHILIC BACTERIUM, THERMOCHROMATIUM TEPIDUM | Descriptor: | 2-O-octyl-beta-D-glucopyranose, BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, ... | Authors: | Nogi, T, Fathir, I, Kobayashi, M, Nozawa, T, Miki, K. | Deposit date: | 2000-05-08 | Release date: | 2000-12-13 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of photosynthetic reaction center and high-potential iron-sulfur protein from Thermochromatium tepidum: thermostability and electron transfer. Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
1ZGW
| NMR structure of E. Coli Ada protein in complex with DNA | Descriptor: | 5'-D(*GP*CP*AP*AP*AP*TP*TP*AP*AP*AP*GP*CP*GP*CP*AP*AP*GP*A)-3', 5'-D(*TP*CP*TP*TP*GP*CP*GP*CP*TP*TP*TP*AP*AP*TP*TP*TP*GP*C)-3', Ada polyprotein, ... | Authors: | He, C, Hus, J.C, Sun, L.J, Zhou, P, Norman, D.P, Doetsch, V, Wei, H, Gross, J.D, Lane, W.S, Wagner, G, Verdine, G.L. | Deposit date: | 2005-04-22 | Release date: | 2005-10-18 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | A Methylation-Dependent Electrostatic Switch Controls DNA Repair and Transcriptional Activation by E. coli Ada. Mol.Cell, 20, 2005
|
|
3VKD
| Crystal structure of MoeO5 soaked with 3-phosphoglycerate | Descriptor: | (2R)-3-(phosphonooxy)-2-{[(2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]oxy}propanoic acid, MAGNESIUM ION, MoeO5, ... | Authors: | Ren, F, Ko, T.-P, Huang, C.-H, Guo, R.-T. | Deposit date: | 2011-11-12 | Release date: | 2012-05-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Insights into the mechanism of the antibiotic-synthesizing enzyme MoeO5 from crystal structures of different complexes Angew.Chem.Int.Ed.Engl., 51, 2012
|
|
4GD7
| Wild-Type Human Thymidylate Synthase with bound Purpurogallin | Descriptor: | 1,2-ETHANEDIOL, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, SULFATE ION, ... | Authors: | Celeste, L.R, Lebioda, L. | Deposit date: | 2012-07-31 | Release date: | 2013-07-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin To be published, 2012
|
|
2D4O
| Crystal structure of TTHA1254 (I68M mutant) from Thermus thermophilus HB8 | Descriptor: | hypothetical protein TTHA1254 | Authors: | Mizohata, E, Uchikubo, T, Kinoshita, Y, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-10-21 | Release date: | 2006-04-21 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of TTHA1254 (I68M mutant) from Thermus thermophilus HB8 To be Published
|
|
1TSY
| THYMIDYLATE SYNTHASE R179K MUTANT | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE | Authors: | Finer-Moore, J, Stroud, R.M. | Deposit date: | 1995-12-05 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase. Protein Eng., 9, 1996
|
|
1U5J
| Propionibacterium shermanii transcarboxylase 5S subunit, Met186Ile | Descriptor: | COBALT (II) ION, transcarboxylase 5S subunit | Authors: | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | Deposit date: | 2004-07-27 | Release date: | 2004-09-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
|
|