5WHK
 
 | | Crystal structure of Fab fragment of antibody DX-2507 bound to FcRn-B2M | | Descriptor: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, ... | | Authors: | Edwards, T.E, Clifton, M.C, Nixon, A.E, Kenniston, J.A. | | Deposit date: | 2017-07-17 | | Release date: | 2017-09-06 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody.
J. Biol. Chem., 292, 2017
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5WER
 | | Crystal Structure of TAPBPR and H2-Dd complex | | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CITRIC ACID, ... | | Authors: | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | | Deposit date: | 2017-07-10 | | Release date: | 2017-10-18 | | Last modified: | 2019-08-28 | | Method: | X-RAY DIFFRACTION (3.412 Å) | | Cite: | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
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5XXY
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5W6G
 | | Human antibody 6649 in complex with influenza hemagglutinin H1 Solomon Islands | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6649 antibody heavy chain, ... | | Authors: | Raymond, D.D, Harrison, S.C. | | Deposit date: | 2017-06-16 | | Release date: | 2017-12-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5W6C
 | | UCA Fab (unbound) from 6649 Lineage | | Descriptor: | UCA Fab heavy chain, UCA Fab light chain | | Authors: | Raymond, D.D, Harrison, S.C. | | Deposit date: | 2017-06-16 | | Release date: | 2017-12-13 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.634 Å) | | Cite: | Conserved epitope on influenza-virus hemagglutinin head defined by a vaccine-induced antibody.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5XSY
 | | Structure of the Nav1.4-beta1 complex from electric eel | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein, Voltage-gated sodium channel beta subunit 1, ... | | Authors: | Yan, Z, Zhou, Q, Wu, J.P, Yan, N. | | Deposit date: | 2017-06-15 | | Release date: | 2017-08-09 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structure of the Nav1.4-beta 1 Complex from Electric Eel.
Cell, 170, 2017
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5XRQ
 | | Crystal structure of human monoclonal antibody H3v-47 | | Descriptor: | Fab H3v-47 heavy chain, Fab H3v-47 light chain | | Authors: | Zhang, H, Willson, I.A. | | Deposit date: | 2017-06-09 | | Release date: | 2018-07-25 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.
Nat Commun, 9, 2018
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5W42
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5XPV
 | | Structure of the V domain of amphioxus IgVJ-C2 | | Descriptor: | amphioxus IgVJ-C2 | | Authors: | Chen, R, Qi, J, Zhang, N, Zhang, L, Yao, S, Wu, Y, Jiang, B, Wang, Z, Yuan, H, Zhang, Q, Xia, C. | | Deposit date: | 2017-06-05 | | Release date: | 2018-04-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Discovery and Analysis of Invertebrate IgVJ-C2 Structure from Amphioxus Provides Insight into the Evolution of the Ig Superfamily.
J. Immunol., 200, 2018
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5XPW
 | | Structure of amphioxus IgVJ-C2 molecule | | Descriptor: | amphioxus IgVJ-C2 | | Authors: | Chen, R, Qi, J, Zhang, N, Zhang, L, Yao, S, Wu, Y, Jiang, B, Wang, Z, Yuan, H, Zhang, Q, Xia, C. | | Deposit date: | 2017-06-05 | | Release date: | 2018-04-18 | | Last modified: | 2018-04-25 | | Method: | X-RAY DIFFRACTION (2.003 Å) | | Cite: | Discovery and Analysis of Invertebrate IgVJ-C2 Structure from Amphioxus Provides Insight into the Evolution of the Ig Superfamily.
J. Immunol., 200, 2018
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5W1M
 | | MACV GP1 CR1-07 Fab complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-07 Fab heavy chain, ... | | Authors: | Raymond, D.D, Clark, L.E, Abraham, J. | | Deposit date: | 2017-06-03 | | Release date: | 2018-05-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.91 Å) | | Cite: | Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018
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5W1K
 | | JUNV GP1 CR1-10 Fab CR1-28 Fab complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-10 Fab heavy chain, ... | | Authors: | Raymond, D.D, Clark, L.E, Abraham, J. | | Deposit date: | 2017-06-03 | | Release date: | 2018-05-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.99 Å) | | Cite: | Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018
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5XP1
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5O4Y
 | | Structure of human PD-L1 in complex with inhibitor | | Descriptor: | PHE-MAA-ASN-PRO-HIS-LEU-SER-TRP-SER-TRP-9KK-9KK-ARG-CCS-GLY-NH2, Programmed cell death 1 ligand 1 | | Authors: | Magiera, K, Grudnik, P, Dubin, G, Holak, T.A. | | Deposit date: | 2017-05-31 | | Release date: | 2017-09-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5W08
 | | A/Texas/50/2012(H3N2) Influenza hemagglutinin in complex with K03.12 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | | Authors: | McCarthy, K.R, Harrison, S.C. | | Deposit date: | 2017-05-30 | | Release date: | 2018-02-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Immunity, 48, 2018
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5W0D
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5VZY
 | | Crystal structure of crenezumab Fab in complex with Abeta | | Descriptor: | Amyloid beta A4 protein, Crenezumab Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Crenezumab Fab light chain,Immunoblobulin light chain | | Authors: | Ultsch, M, Wang, W. | | Deposit date: | 2017-05-29 | | Release date: | 2017-08-09 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin.
Sci Rep, 6, 2016
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5VZX
 | | Crystal structure of crenezumab Fab | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Crenezumab Fab heavy chain, ... | | Authors: | Ultsch, M, Wang, W. | | Deposit date: | 2017-05-29 | | Release date: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin.
Sci Rep, 6, 2016
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5XOF
 | | Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide I | | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Paired immunoglobulin-like type 2 receptor alpha, Peptide from Nitric oxide synthase, ... | | Authors: | Furukawa, A, Kakita, K, Yamada, T, Ishizuka, M, Sakamoto, J, Hatori, N, Maeda, N, Ohsaka, F, Saitoh, T, Nomura, T, Kuroki, K, Nambu, H, Arase, H, Matsunaga, H, Anada, M, Ose, T, Hashimoto, S, Maenaka, K. | | Deposit date: | 2017-05-28 | | Release date: | 2017-10-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.963 Å) | | Cite: | Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor.
J. Biol. Chem., 292, 2017
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5O45
 | | Structure of human PD-L1 in complex with inhibitor | | Descriptor: | PHE-MEA-9KK-SAR-ASP-VAL-MEA-TYR-SAR-TRP-TYR-LEU-CCS-GLY-NH2, Programmed cell death 1 ligand 1 | | Authors: | Magiera, K, Grudnik, P, Dubin, G, Holak, T.A. | | Deposit date: | 2017-05-26 | | Release date: | 2017-09-20 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (0.99 Å) | | Cite: | Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.
Angew. Chem. Int. Ed. Engl., 56, 2017
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5XO2
 | | Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide II | | Descriptor: | N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2,4-dideoxy-alpha-D-xylo-hexopyranose, Paired immunoglobulin-like type 2 receptor alpha, Peptide from Envelope glycoprotein B | | Authors: | Furukawa, A, Kakita, K, Yamada, T, Ishizuka, M, Sakamoto, J, Hatori, N, Maeda, N, Ohsaka, F, Saitoh, T, Nomura, T, Kuroki, K, Nambu, H, Arase, H, Matsunaga, S, Anada, M, Ose, T, Hashimoto, S, Maenaka, K. | | Deposit date: | 2017-05-25 | | Release date: | 2017-10-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor.
J. Biol. Chem., 292, 2017
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5VXR
 | | The antigen-binding fragment of MAb24 in complex with a peptide from Hepatitis C Virus E2 epitope I (412-423) | | Descriptor: | GLYCEROL, MAb24 Variable Heavy Chain,MAb24 Variable Heavy Chain, MAb24 Variable Light Chain,MAb24 Variable Light Chain, ... | | Authors: | Hardy, J.M, Gu, J, Boo, I, Drummer, H.E, Coulibaly, F.J. | | Deposit date: | 2017-05-24 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes.
J. Virol., 92, 2018
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5O1R
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5VST
 | | Crystal structure of murine CEACAM1b | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Biliary glycoprotein | | Authors: | Peng, G, Yang, Y, Pasquarella, J.R, Xu, L, Qian, Z, Holmes, K.V, Li, F. | | Deposit date: | 2017-05-12 | | Release date: | 2017-05-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Molecular mechanism for coronavirus-driven evolution of mouse receptor
J. Biol. Chem., 292, 2017
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5VSI
 | | CH1/Ckappa Fab mutant 15.1 | | Descriptor: | 1,2-ETHANEDIOL, CH1/Ckappa Fab heavy chain, CH1/Ckappa Fab light chain, ... | | Authors: | Hendle, J. | | Deposit date: | 2017-05-11 | | Release date: | 2017-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Computational design of a specific heavy chain/ kappa light chain interface for expressing fully IgG bispecific antibodies.
Protein Sci., 26, 2017
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