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1O7V
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High resolution structure of Siglec-7
Descriptor: SIALIC ACID BINDING IG-LIKE LECTIN 7, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Alphey, M.S, Attrill, H, Crocker, P.R, Van Aalten, D.M.F.
Deposit date:2002-11-14
Release date:2003-03-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family.
J.Biol.Chem., 278, 2003
1OHQ
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Crystal structure of HEL4, a soluble human VH antibody domain resistant to aggregation
Descriptor: IMMUNOGLOBULIN
Authors:Jespers, L, Schon, O, James, L.C, Veprintsev, D, Winter, G.
Deposit date:2003-05-30
Release date:2004-03-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Hel4, a Soluble, Refoldable Human V(H) Single Domain with a Germ-Line Scaffold
J.Mol.Biol., 337, 2004
1NKO
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Energetic and structural basis of sialylated oligosaccharide recognition by the natural killer cell inhibitory receptor p75/AIRM1 or Siglec-7
Descriptor: Sialic acid binding Ig-like lectin 7
Authors:Dimasi, N, Attril, H, van Aalten, D.M.F, Moretta, L, Biassoni, R, Mariuzza, R.A.
Deposit date:2003-01-03
Release date:2003-04-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1.
Acta Crystallogr.,Sect.D, 60, 2004
1QBL
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FAB E8 (FABE8A) X-RAY STRUCTURE AT 2.26 ANGSTROM RESOLUTION
Descriptor: FABE8A
Authors:Mylvaganam, S.E, Paterson, Y, Getzoff, E.D.
Deposit date:1998-04-29
Release date:1998-12-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution.
J.Mol.Biol., 281, 1998
1QFP
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N-TERMINAL DOMAIN OF SIALOADHESIN (MOUSE)
Descriptor: PROTEIN (SIALOADHESIN)
Authors:May, A.P, Robinson, R.C, Burtnick, L, Crocker, P.R, Jones, E.Y.
Deposit date:1999-04-12
Release date:1999-04-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution.
Mol.Cell, 1, 1998
1QD0
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CAMELID HEAVY CHAIN VARIABLE DOMAINS PROVIDE EFFICIENT COMBINING SITES TO HAPTENS
Descriptor: 3-HYDROXY-7-(4-{1-[2-HYDROXY-3-(2-HYDROXY-5-SULFO-PHENYLAZO)-BENZYL]-2-SULFO-ETHYLAMINO}-[1,2,5]TRIAZIN-2-YLAMINO)-2-(2-HYDROXY-5-SULFO-PHENYLAZO)-NAPTHALENE-1,8-DISULFONIC ACID, COPPER (II) ION, VHH-R2 ANTI-RR6 ANTIBODY
Authors:Spinelli, S, Frenken, L.G.J, Hermans, P, Verrips, T, Brown, K, Tegoni, M, Cambillau, C.
Deposit date:1999-07-08
Release date:2000-07-19
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Camelid heavy-chain variable domains provide efficient combining sites to haptens.
Biochemistry, 39, 2000
1ODA
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N-terminal of Sialoadhesin in complex with Me-a-9-N-(biphenyl-4-carbonyl)-amino-9-deoxy-Neu5Ac (BIP compound)
Descriptor: ME-A-9-N-(BIPHENYL-4-CARBONYL)-AMINO-9-DEOXY-NEU5AC, SIALOADHESIN
Authors:Zaccai, N.R, Maenaka, K, Maenaka, T, Crocker, P.R, Brossmer, R, Kelm, S, Jones, E.Y.
Deposit date:2003-02-14
Release date:2003-08-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Structure Guided Design of Sialic Acid-Based Siglec Inhibitors and Crystallographic Analysis in Complex with Sialoadhesin
Structure, 11, 2003
1OD7
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N-terminal of Sialoadhesin in complex with Me-a-9-N-(naphthyl-2-carbonyl)-amino-9-deoxy-Neu5Ac (NAP compound)
Descriptor: ME-A-9-N-(NAPHTHYL-2-CARBONYL)-AMINO-9-DEOXY-NEU5AC, SIALOADHESIN
Authors:Zaccai, N.R, Maenaka, K, Maenaka, T, Crocker, P.R, Brossmer, R, Kelm, S, Jones, E.Y.
Deposit date:2003-02-14
Release date:2003-05-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Guided Design of Sialic Acid-Based Siglec Inhibitors and Crystallographic Analysis in Complex with Sialoadhesin
Structure, 11, 2003
1OAY
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Antibody multispecificity mediated by conformational diversity
Descriptor: Furazolidone, IMMUNOGLOBULIN E
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-01-21
Release date:2004-01-15
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1QA9
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Structure of a Heterophilic Adhesion Complex Between the Human CD2 and CD58(LFA-3) Counter-Receptors
Descriptor: HUMAN CD2 PROTEIN, HUMAN CD58 PROTEIN
Authors:Wang, J.-H, Smolyar, A, Tan, K, Liu, J.-H, Kim, M, Sun, Z.J, Wagner, G, Reinherz, E.L.
Deposit date:1999-04-13
Release date:1999-04-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors.
Cell(Cambridge,Mass.), 97, 1999
1QFO
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N-TERMINAL DOMAIN OF SIALOADHESIN (MOUSE) IN COMPLEX WITH 3'SIALYLLACTOSE
Descriptor: N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, PROTEIN (SIALOADHESIN)
Authors:May, A.P, Robinson, R.C, Vinson, M, Crocker, P.R, Jones, E.Y.
Deposit date:1999-04-12
Release date:1999-04-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the N-terminal domain of sialoadhesin in complex with 3' sialyllactose at 1.85 A resolution.
Mol.Cell, 1, 1998
1OAQ
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Free conformation Ab1 of the IgE SPE-7
Descriptor: HEAVY CHAIN, LIGHT CHAIN
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-01-21
Release date:2004-01-15
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1OCW
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BU of 1ocw by Molmil
Free conformation Ab2 of the IgE SPE-7
Descriptor: IMMUNOGLOBULIN E
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-02-11
Release date:2004-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1QOK
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BU of 1qok by Molmil
MFE-23 AN ANTI-CARCINOEMBRYONIC ANTIGEN SINGLE-CHAIN FV ANTIBODY
Descriptor: MFE-23 RECOMBINANT ANTIBODY FRAGMENT
Authors:Boehm, M.K, Corper, A.L, Wan, T, Sohi, M.K, Sutton, B.J, Thornton, J.D, Keep, P.A, Chester, K.A, Begent, R.H.J, Perkins, S.J.
Deposit date:1999-11-11
Release date:2000-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Anti-Carcinoembryonic Antigen Single-Chain Fv Antibody Mfe-23 and a Model for Antigen Binding Based on Intermolecular Contacts
Biochem.J., 346, 2000
1QP1
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KAPPA VARIABLE LIGHT CHAIN
Descriptor: BENCE-JONES KAPPA I ANTIBODY BRE (LIGHT CHAIN)
Authors:Steinrauf, L.K.
Deposit date:1999-05-30
Release date:1999-06-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Molecular structure of the amyloid-forming protein kappa I Bre.
J.Biochem.(Tokyo), 125, 1999
1Q8M
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BU of 1q8m by Molmil
Crystal structure of the human myeloid cell activating receptor TREM-1
Descriptor: GLUTATHIONE, SULFATE ION, triggering receptor expressed on myeloid cells 1
Authors:Radaev, S, Kattah, M, Rostro, B, Colonna, M, Sun, P.D.
Deposit date:2003-08-21
Release date:2003-12-09
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the human myeloid cell activating receptor TREM-1
Structure, 11, 2003
1OAX
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BU of 1oax by Molmil
Fv Structure of the IgE SPE-7 in complex with acenaphthenequinone
Descriptor: ACENAPHTHENEQUINONE, IMMUNOGLOBULIN E
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-01-21
Release date:2004-01-15
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1OD9
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BU of 1od9 by Molmil
N-terminal of Sialoadhesin in complex with Me-a-9-N-benzoyl-amino-9-deoxy-Neu5Ac (BENZ compound)
Descriptor: SIALOADHESIN, SULFATE ION, methyl 5-acetamido-3,5,9-trideoxy-9-[(phenylcarbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid
Authors:Zaccai, N.R, Maenaka, K, Maenaka, T, Crocker, P.R, Brossmer, R, Kelm, S, Jones, E.Y.
Deposit date:2003-02-14
Release date:2003-05-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Guided Design of Sialic Acid-Based Siglec Inhibitors and Crystallographic Analysis in Complex with Sialoadhesin
Structure, 11, 2003
1OAR
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Fv IgE SPE-7 in complex with Alizarin Red
Descriptor: 1,2-ETHANEDIOL, ALIZARIN RED, CACODYLATE ION, ...
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-01-21
Release date:2004-01-15
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
1QAC
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CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE
Descriptor: IMMUNOGLOBULIN LIGHT CHAIN VARIABLE DOMAIN
Authors:Pokkuluri, P.R, Cai, X, Johnson, G, Stevens, F.J, Schiffer, M.
Deposit date:1999-02-25
Release date:2000-02-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface.
Protein Sci., 9, 2000
1PKO
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Myelin Oligodendrocyte Glycoprotein (MOG)
Descriptor: Myelin Oligodendrocyte Glycoprotein
Authors:Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U.
Deposit date:2003-06-06
Release date:2003-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein
Proc.Natl.Acad.Sci.USA, 100, 2003
1Q0Y
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Anti-Morphine Antibody 9B1 Complexed with Morphine
Descriptor: (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, Fab 9B1, Heavy chain, ...
Authors:Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D.
Deposit date:2003-07-17
Release date:2004-04-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine
J.Mol.Biol., 337, 2004
1PY9
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The crystal structure of an autoantigen in multiple sclerosis
Descriptor: Myelin-oligodendrocyte glycoprotein, SULFATE ION
Authors:Clements, C.S, Reid, H.H, Beddoe, T, Tynan, F.E, Perugini, M.A, Johns, T.G, Bernard, C.C, Rossjohn, J.
Deposit date:2003-07-08
Release date:2003-09-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis
Proc.Natl.Acad.Sci.USA, 100, 2003
1QBM
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FAB E8B ANTIBODY, X-RAY STRUCTURE AT 2.37 ANGSTROMS RESOLUTION
Descriptor: E8B ANTIBODY
Authors:Mylvaganam, S.E, Paterson, Y, Getzoff, E.D.
Deposit date:1998-05-01
Release date:1999-01-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution.
J.Mol.Biol., 281, 1998
1REI
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THE MOLECULAR STRUCTURE OF A DIMER COMPOSED OF THE VARIABLE PORTIONS OF THE BENCE-JONES PROTEIN REI REFINED AT 2.0 ANGSTROMS RESOLUTION
Descriptor: BENCE-JONES PROTEIN REI (LIGHT CHAIN)
Authors:Epp, O, Lattman, E.E, Colman, P, Fehlhammer, H, Bode, W, Schiffer, M, Huber, R, Palm, W.
Deposit date:1976-03-17
Release date:1976-05-19
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution.
Biochemistry, 14, 1975

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