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1PLR	CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) Authors: Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J. Deposit date: 1995-01-02 Release date: 1995-03-31 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell(Cambridge,Mass.), 79, 1994
2OD8	Structure of a peptide derived from Cdc9 bound to PCNA Descriptor: DNA ligase I, mitochondrial precursor, Proliferating cell nuclear antigen Authors: Chapados, B.R, Tainer, J.A. Deposit date: 2006-12-21 Release date: 2007-05-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.8 Å) Cite: The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase. Nucleic Acids Res., 35, 2007
7EP8	Crystal structure of PCNA from Neurospora crassa Descriptor: Proliferating cell nuclear antigen Authors: Sundaram, R, Vasudevan, D. Deposit date: 2021-04-26 Release date: 2021-06-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA. J.Biol.Chem., 297, 2021
6O09	Structure of AtPCNA in complex with the PIP motif of ATXR6 Descriptor: Proliferating cellular nuclear antigen 1, Uncharacterized protein Authors: Couture, J.F, Davarinejad, H. Deposit date: 2019-02-15 Release date: 2019-03-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.06 Å) Cite: ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle. J. Mol. Biol., 431, 2019
5E0T	Human PCNA mutant - S228I Descriptor: Proliferating cell nuclear antigen Authors: Duffy, C.M, Hilbert, B.J, Kelch, B.A. Deposit date: 2015-09-29 Release date: 2016-04-20 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.6653 Å) Cite: A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
9F6E	Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation) Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ... Authors: Roske, J.J, Yeeles, J.T.P. Deposit date: 2024-05-01 Release date: 2024-08-07 Method: ELECTRON MICROSCOPY (3.74 Å) Cite: Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
9F6D	Human DNA polymerase epsilon bound to DNA and PCNA (open conformation) Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ... Authors: Roske, J.J, Yeeles, J.T.P. Deposit date: 2024-05-01 Release date: 2024-08-07 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
9F6F	Human DNA polymerase epsilon bound to DNA and PCNA (closed conformation) Descriptor: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ... Authors: Roske, J.J, Yeeles, J.T.P. Deposit date: 2024-05-01 Release date: 2024-08-07 Method: ELECTRON MICROSCOPY (3.75 Å) Cite: Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
1IZ4	Pyrococcus furiosus PCNA mutant (Met73Leu/Asp143Ala): tetragonal form Descriptor: Proliferating cell nuclear antigen Authors: Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. Deposit date: 2002-09-21 Release date: 2003-04-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA PROTEIN SCI., 12, 2003
1ISQ	Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide Descriptor: Proliferating Cell Nuclear Antigen, replication factor C large subunit Authors: Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. Deposit date: 2001-12-19 Release date: 2002-10-23 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus Genes Cells, 7, 2002
1IZ5	Pyrococcus furiosus PCNA mutant (Met73Leu, Asp143Ala, Asp147Ala): orthorhombic form Descriptor: Proliferating cell nuclear antigen Authors: Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K. Deposit date: 2002-09-23 Release date: 2003-04-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA PROTEIN SCI., 12, 2003
1W60	NATIVE HUMAN PCNA Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN Authors: Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M. Deposit date: 2004-08-11 Release date: 2005-01-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.15 Å) Cite: Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102, 2005
1VYM	NATIVE HUMAN PCNA Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN Authors: Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M. Deposit date: 2004-05-03 Release date: 2005-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102, 2005
1VYJ	Structural and biochemical studies of human PCNA complexes provide the basis for association with CDK/cyclin and rationale for inhibitor design Descriptor: PROLIFERATING CELL NUCLEAR ANTIGEN, SMALL PEPTIDE SAVLQKKITDYFHPKK Authors: Kontopidis, G, Wu, S, Zheleva, D, Taylor, P, Mcinnes, C, Lane, D, Fischer, P, Walkinshaw, M.D. Deposit date: 2004-04-30 Release date: 2005-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural and Biochemical Studies of Human Proliferating Cell Nuclear Antigen Complexes Provide a Rationale for Cyclin Association and Inhibitor Design Proc.Natl.Acad.Sci.USA, 102, 2005
5H0T	Crystal structure of proliferating cell nuclear antigen from Leishmania donovani at 2.73 Angstrom resolution Descriptor: DI(HYDROXYETHYL)ETHER, Proliferating cell nuclear antigen Authors: Singh, P.K, Yadav, S.P, Sharma, P.S, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2016-10-06 Release date: 2016-11-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.73 Å) Cite: Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani. Biochim. Biophys. Acta, 1865, 2017
6W9W	R80A PCNA mutant defective in BIR Descriptor: Proliferating cell nuclear antigen Authors: Ripley, B.M, Washington, M.T. Deposit date: 2020-03-23 Release date: 2020-09-23 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A To be Published
6VVO	Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA) Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A. Deposit date: 2020-02-18 Release date: 2020-02-26 Last modified: 2020-03-25 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism Biorxiv, 2020
6WAC	FF248-249AA PCNA mutant defective in BIR Descriptor: Proliferating cell nuclear antigen Authors: Ripley, B.M, Washington, M.T. Deposit date: 2020-03-25 Release date: 2020-09-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A To be Published
6QC0	PCNA complex with Cdt2 C-terminal PIP-box peptide Descriptor: Denticleless protein homolog, Proliferating cell nuclear antigen Authors: Perrakis, A.P, von Castelmur, E. Deposit date: 2018-12-25 Release date: 2019-01-23 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1. Life Sci Alliance, 1, 2018
6QCG	PCNA complex with Cdt1 N-terminal PIP-box peptide Descriptor: DNA replication factor Cdt1, Proliferating cell nuclear antigen Authors: Perrakis, A, von Castelmur, E. Deposit date: 2018-12-28 Release date: 2019-01-23 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1. Life Sci Alliance, 1, 2018
6QH1	The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide Descriptor: Proliferating cell nuclear antigen, S-phase delaying protein 1 Authors: Kragelund, B.B, Nielsen, O, Olsen, J.G, Kassem, N, Prestel, A. Deposit date: 2019-01-14 Release date: 2020-02-05 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The structure of Schizosaccharomyces pombe PCNA in complex with an Spd1 derived peptide To Be Published
5HAC	Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution Descriptor: Proliferating cell nuclear antigen Authors: Singh, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. Deposit date: 2015-12-30 Release date: 2016-03-23 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution To Be Published
5MLW	Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide Descriptor: APIM motif peptide, Proliferating cell nuclear antigen, SULFATE ION Authors: Ariza, A. Deposit date: 2016-12-07 Release date: 2017-06-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017
5MAV	Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide. Descriptor: Poly (ADP-ribose) glycohydrolase, Proliferating cell nuclear antigen Authors: Grishkovskaya, I, Djinovic-Carugo, K, Slade, D. Deposit date: 2016-11-06 Release date: 2017-08-02 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.575 Å) Cite: A novel non-canonical PIP-box mediates PARG interaction with PCNA. Nucleic Acids Res., 45, 2017
5MLO	Crystal structure of human PCNA in complex with ZRANB3 PIP box peptide Descriptor: Proliferating cell nuclear antigen, SODIUM ION, ZRANB3 PIP box peptide Authors: Ariza, A. Deposit date: 2016-12-07 Release date: 2017-06-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017

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