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1LBL	Crystal structure of indole-3-glycerol phosphate synthase (IGPS) in complex with 1-(o-carboxyphenylamino)-1-deoxyribulose 5'-phosphate (CdRP) Descriptor: 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, indole-3-glycerol phosphate synthase Authors: Hennig, M, Darimont, B.D, Kirschner, K, Jansonius, J.N. Deposit date: 2002-04-04 Release date: 2002-09-18 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The catalytic mechanism of indole-3-glycerol phosphate synthase: Crystal structures of complexes of the enzyme from Sulfolobus solfataricus with the substrate analogue, substrate, and product J.Mol.Biol., 319, 2002
1LBF	CRYSTAL STRUCTURE OF INDOLE-3-GLYCEROL PHOSPHATE SYNTASE (IGPS)WITH REDUCED 1-(O-CABOXYPHENYLAMINO)-1-DEOXYRIBULOSE 5-PHOSPHATE (RCDRP) Descriptor: 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE Authors: Hennig, M, Darimont, B, Kirschner, K, Jansonius, J.N. Deposit date: 2002-04-03 Release date: 2002-06-12 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.05 Å) Cite: The catalytic mechanism of indole-3-glycerol phosphate synthase: crystal structures of complexes of the enzyme from Sulfolobus solfataricus with substrate analogue, substrate, and product. J.Mol.Biol., 319, 2002
3QJA	Crystal Structure of the Mycobacterium tuberculosis Indole-3-glycerol phosphate synthase (TrpC) in apo form Descriptor: Indole-3-glycerol phosphate synthase, SULFATE ION Authors: Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2011-01-28 Release date: 2011-06-15 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.29 Å) Cite: Small-molecule scaffolds for Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) inhibitors identified by high-throughput screening and defined by X-ray crystallography To be Published
3T55	Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with Phenoxymethyl Benzoic Acid (PMBA) Descriptor: 3-(phenoxymethyl)benzoic acid, Indole-3-glycerol phosphate synthase, MALONATE ION, ... Authors: Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2011-07-26 Release date: 2012-08-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published
3T40	Crystal Structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) complex with N-2-Carboxyphenyl Glycine (CPG) Descriptor: 2-[(carboxymethyl)amino]benzoic acid, Indole-3-glycerol phosphate synthase, SULFATE ION Authors: Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2011-07-25 Release date: 2012-08-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.752 Å) Cite: Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published
3TC6	Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR63. Descriptor: DI(HYDROXYETHYL)ETHER, Indole-3-glycerol phosphate synthase, PHOSPHATE ION Authors: Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) Deposit date: 2011-08-08 Release date: 2011-08-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design. J.Mol.Biol., 426, 2014
3TC7	Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR62. Descriptor: ACETIC ACID, Indole-3-glycerol phosphate synthase, PHOSPHATE ION Authors: Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) Deposit date: 2011-08-08 Release date: 2011-08-24 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design. J.Mol.Biol., 426, 2014
3T44	Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with indole glycerol phosphate (IGP) amd anthranilate Descriptor: 2-AMINOBENZOIC ACID, INDOLE-3-GLYCEROL PHOSPHATE, Indole-3-glycerol phosphate synthase Authors: Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2011-07-25 Release date: 2012-08-08 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published
3T78	Crystal Structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in Complex with 5-Fluoroanthranilate Descriptor: 2-amino-5-fluorobenzoic acid, ACETATE ION, Indole-3-glycerol phosphate synthase, ... Authors: Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2011-07-29 Release date: 2012-08-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published
3TSM	Crystal structure of Indole-3-glycerol phosphate synthase from Brucella melitensis Descriptor: GLYCEROL, Indole-3-glycerol phosphate synthase, SULFATE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2011-09-13 Release date: 2011-10-05 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of Indole-3-glycerol phosphate synthase from Brucella melitensis To be Published
1PII	THREE-DIMENSIONAL STRUCTURE OF THE BIFUNCTIONAL ENZYME PHOSPHORIBOSYLANTHRANILATE ISOMERASE: INDOLEGLYCEROLPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI REFINED AT 2.0 ANGSTROMS RESOLUTION Descriptor: N-(5'PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE, PHOSPHATE ION Authors: Wilmanns, M, Priestle, J.P, Jansonius, J.N. Deposit date: 1991-06-21 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Three-dimensional structure of the bifunctional enzyme phosphoribosylanthranilate isomerase: indoleglycerolphosphate synthase from Escherichia coli refined at 2.0 A resolution. J.Mol.Biol., 223, 1992
7ETX	Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (TrpC) from corynebacterium glutamicum Descriptor: GLYCEROL, Tryptophan biosynthesis protein TrpCF Authors: Prak, W.J, Kim, K.-J. Deposit date: 2021-05-15 Release date: 2022-05-11 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structure and Functional Characterization of the Bifunctional N -(5'-Phosphoribosyl)anthranilate Isomerase-indole-3-glycerol-phosphate Synthase from Corynebacterium glutamicum J.Agric.Food Chem., 69, 2021
7ETY	Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpC) from Corynebacterium glutamicum in complex with reduced 1-(O-carboxyphenylamino)-1-deoxyribulose 5-phosphate (rCdRP) Descriptor: 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, GLYCEROL, Tryptophan biosynthesis protein TrpCF Authors: Park, W.J, Kim, K.-J. Deposit date: 2021-05-15 Release date: 2022-05-11 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Crystal Structure and Functional Characterization of the Bifunctional N -(5'-Phosphoribosyl)anthranilate Isomerase-indole-3-glycerol-phosphate Synthase from Corynebacterium glutamicum J.Agric.Food Chem., 69, 2021

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