3T40
Crystal Structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) complex with N-2-Carboxyphenyl Glycine (CPG)
Summary for 3T40
Entry DOI | 10.2210/pdb3t40/pdb |
Related | 3QJA 3T44 3T55 3T78 |
Descriptor | Indole-3-glycerol phosphate synthase, 2-[(carboxymethyl)amino]benzoic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | indole-3-glycerol phosphate synthase (igps), tryptophan biosynthesis, structural genomics, tb structural genomics consortium, tbsgc, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 28440.38 |
Authors | Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2011-07-25, release date: 2012-08-08, Last modification date: 2023-09-13) |
Primary citation | Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C. Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published, |
Experimental method | X-RAY DIFFRACTION (1.752 Å) |
Structure validation
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