3T44

Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with indole glycerol phosphate (IGP) amd anthranilate

Summary for 3T44

• Entry DOI: 10.2210/pdb3t44/pdb
• Related: 3QJA 3T40 3T55 3T78
• Descriptor: Indole-3-glycerol phosphate synthase, INDOLE-3-GLYCEROL PHOSPHATE, 2-AMINOBENZOIC ACID, ... (4 entities in total)
• Functional Keywords: mycobacterium tuberculosis indole glycerol phosphate synthase (igps), tryptophan biosynthesis, structural genomics, tb structural genomics consortium, tbsgc, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 28477.43

Authors

Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2011-07-25, release date: 2012-08-08, Last modification date: 2023-11-15)

• Primary citation: Reddy, M.C.M.,Bruning, J.B.,Thurman, C.,Sacchettini, J.C.; Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis; To be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)