8HC6
 
 | | SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with YB9-258 Fab, focused refinement of Fab region | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of YB9-258 Fab, Light chain of YB9-258, ... | | Authors: | Liu, B, Gao, X, Chen, Q, Li, Z, Su, M, He, J, Xiong, X. | | Deposit date: | 2022-11-01 | | Release date: | 2023-01-25 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (4.69 Å) | | Cite: | Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants.
Nat Commun, 14, 2023
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4FQ1
 | | Crystal Structure of PGT121 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain | | Authors: | Scharf, L, Bjorkman, P.J. | | Deposit date: | 2012-06-24 | | Release date: | 2012-11-14 | | Last modified: | 2021-05-19 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
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6XOC
 | | Crystal structure of glVRC01 Fab in complex with anti-idiotypic iv4 Fab | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Aljedani, S.S, Weidle, C, Pancera, M. | | Deposit date: | 2020-07-06 | | Release date: | 2021-03-31 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
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3J8V
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8HC9
 | | SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 3 YB13-292 Fabs (3 RBD down) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of YB13-292 Fab, ... | | Authors: | Liu, B, Gao, X, Chen, Q, Li, Z, Su, M, He, J, Xiong, X. | | Deposit date: | 2022-11-01 | | Release date: | 2023-01-25 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (6.03 Å) | | Cite: | Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants.
Nat Commun, 14, 2023
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8HC2
 | | SARS-CoV-2 Omicron BA.1 spike trimer (6P) in complex with 1 YB9-258 Fab (1 RBD up) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of YB9-258 Fab, ... | | Authors: | Liu, B, Gao, X, Chen, Q, Li, Z, Su, M, He, J, Xiong, X. | | Deposit date: | 2022-11-01 | | Release date: | 2023-01-25 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (6.21 Å) | | Cite: | Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants.
Nat Commun, 14, 2023
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3J8Z
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3J8W
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4FQ2
 | | Crystal Structure of 10-1074 Fab | | Descriptor: | 1,2-ETHANEDIOL, Fab heavy chain, Fab light chain, ... | | Authors: | Scharf, L, Bjorkman, P.J. | | Deposit date: | 2012-06-24 | | Release date: | 2012-11-14 | | Last modified: | 2021-05-19 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FQC
 | | Crystal Structure of PGT121 Fab Bound to a complex-type sialylated N-glycan | | Descriptor: | Fab heavy chain, Fab light chain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Scharf, L, Bjorkman, P.J. | | Deposit date: | 2012-06-25 | | Release date: | 2012-11-14 | | Last modified: | 2021-05-19 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4HKZ
 | | Trastuzumab Fab complexed with Protein L and Protein A fragments | | Descriptor: | CHLORIDE ION, Immunoglobulin G-binding protein A, Protein L fragment, ... | | Authors: | Avery, K.N, Zer, C, Bzymek, K.P, Williams, J.C. | | Deposit date: | 2012-10-15 | | Release date: | 2013-10-09 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4H88
 | | Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230 | | Descriptor: | Major prion protein, POM1 FAB CHAIN H, POM1 FAB CHAIN L, ... | | Authors: | Baral, P.K, Wieland, B, Swayampakula, M, James, M.N. | | Deposit date: | 2012-09-21 | | Release date: | 2013-07-31 | | Last modified: | 2013-09-18 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Nature, 501, 2013
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4HJG
 | | Meditope-enabled trastuzumab | | Descriptor: | Immunoglobulin G-binding protein A, Protein L fragment, Trastuzumab heavy chain, ... | | Authors: | Donaldson, J.M, Zer, C, Avery, K.N, Bzymek, K.P, Horne, D.A, Williams, J.C. | | Deposit date: | 2012-10-12 | | Release date: | 2013-10-09 | | Last modified: | 2013-11-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
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8FZO
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8G19
 | | Crystal structure of monoreactive 4C05 human Fab | | Descriptor: | Heavy chain of anti-influenza human 4C05 Fab fragment, Light chain of anti-influenza human 4C05 Fab fragment | | Authors: | Borowska, M.T, Adams, E.J. | | Deposit date: | 2023-02-01 | | Release date: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
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8G1B
 | | Crystal structure of polyreactive 2G02 human Fab | | Descriptor: | The heavy chain of human 2G02 Fab fragment, The light chain of human 2G02 Fab fragment | | Authors: | Borowska, M.T, Adams, E.J. | | Deposit date: | 2023-02-01 | | Release date: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
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8G1C
 | | Crystal structure of polyreactive 3B03 human Fab | | Descriptor: | Heavy chain of monoreactive 3B03 human Fab fragment, Light chain of monoreactive 3B03 human Fab fragment | | Authors: | Borowska, M.T, Adams, E.J. | | Deposit date: | 2023-02-01 | | Release date: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
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8FZP
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8G6B
 | | Crystal structure of PfAMA1-RON2L chimera | | Descriptor: | Apical membrane antigen 1, rhoptry neck protein 2 chimera, SULFATE ION | | Authors: | Boulanger, M.J, Ramaswamy, R. | | Deposit date: | 2023-02-14 | | Release date: | 2023-09-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structure guided mimicry of an essential P. falciparum receptor-ligand complex enhances cross neutralizing antibodies.
Nat Commun, 14, 2023
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6LHP
 | | The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab 14B10 | | Descriptor: | SPHINGOSINE, VP1 protein, VP2 protein, ... | | Authors: | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | | Deposit date: | 2019-12-09 | | Release date: | 2020-02-05 | | Last modified: | 2020-02-26 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16.
Cell Host Microbe, 27, 2020
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4IOI
 | | Meditope-enabled trastuzumab in complex with CQFDLSTRRLKC | | Descriptor: | Immunoglobulin G-binding protein A, Protein L, Trastuzumab heavy chain, ... | | Authors: | Bzymek, K.P, Zer, C, Avery, K.N, Williams, J.C. | | Deposit date: | 2013-01-07 | | Release date: | 2013-10-09 | | Last modified: | 2013-11-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 110, 2013
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8FDO
 | | SARS-CoV-2 fusion peptide epitope scaffold FP15 bound to DH1058 | | Descriptor: | DH1058 Heavy chain, DH1058 Light chain, FP15 | | Authors: | Kapingidza, A.B, Marston, D.J, Wrapp, D, Winters, K, Azoitei, M.L. | | Deposit date: | 2022-12-04 | | Release date: | 2023-10-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Nat Commun, 14, 2023
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5W1M
 | | MACV GP1 CR1-07 Fab complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-07 Fab heavy chain, ... | | Authors: | Raymond, D.D, Clark, L.E, Abraham, J. | | Deposit date: | 2017-06-03 | | Release date: | 2018-05-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.91 Å) | | Cite: | Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018
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5W1G
 | | CR1-07 unliganded Fab | | Descriptor: | CR1-07 Fab heavy chain, CR1-07 Fab light chain | | Authors: | Raymond, D.D, Clark, L.E, Abraham, J. | | Deposit date: | 2017-06-03 | | Release date: | 2018-05-30 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018
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5W1K
 | | JUNV GP1 CR1-10 Fab CR1-28 Fab complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-10 Fab heavy chain, ... | | Authors: | Raymond, D.D, Clark, L.E, Abraham, J. | | Deposit date: | 2017-06-03 | | Release date: | 2018-05-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.99 Å) | | Cite: | Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses.
Nat Commun, 9, 2018
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