7SZU
 
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2N8M
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7QSH
 | | 23S ribosomal RNA Sarcin Ricin Loop 27-nt fragment containing a Xanthosine residue at position 2648 | | Descriptor: | 23S ribosomal RNA Sarcin Ricin Loop 27-nucleotide fragment, 9-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-[[tris(oxidanyl)-$l^{5}-phosphanyl]oxymethyl]oxolan-2-yl]-2-oxidanyl-1~{H}-purin-6-one, GLYCEROL, ... | | Authors: | Ennifar, E, Micura, R. | | Deposit date: | 2022-01-13 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (0.86 Å) | | Cite: | Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA.
Nucleic Acids Res., 50, 2022
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7QUA
 | | Duplex RNA containing Xanthosine-Cytosine base pairs | | Descriptor: | MAGNESIUM ION, RNA (5'-R(*CP*GP*CP*GP*(XAN)P*AP*UP*UP*AP*GP*CP*G)-3'), SODIUM ION | | Authors: | Ennifar, E, Micura, R. | | Deposit date: | 2022-01-17 | | Release date: | 2023-01-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA.
Nucleic Acids Res., 50, 2022
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4ITS
 | | Crystal structure of the catalytic domain of human Pus1 with MES in the active site | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, tRNA pseudouridine synthase A, ... | | Authors: | Czudnochowski, N, Finer-Moore, J.S, Stroud, R.M. | | Deposit date: | 2013-01-18 | | Release date: | 2013-06-05 | | Last modified: | 2013-10-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities.
J.Mol.Biol., 425, 2013
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7MKT
 | | Crystal structure of r(GU)11G-NMM complex | | Descriptor: | N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3') | | Authors: | Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E. | | Deposit date: | 2021-04-26 | | Release date: | 2022-11-02 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | An atypical RNA quadruplex marks RNAs as vectors for gene silencing.
Nat.Struct.Mol.Biol., 29, 2022
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6OMV
 | | CryoEM structure of the LbCas12a-crRNA-AcrVA4-DNA complex | | Descriptor: | AcrVA4, Cpf1, DNA (5'-D(*CP*GP*TP*CP*CP*TP*TP*TP*AP*GP*GP*A)-3'), ... | | Authors: | Chang, L, Li, Z, Zhang, H. | | Deposit date: | 2019-04-19 | | Release date: | 2019-06-12 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Cell Host Microbe, 25, 2019
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7UU4
 | | Crystal structure of APOBEC3G complex with ssRNA | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*AP*AP*UP*UP*U)-3'), SULFATE ION, ... | | Authors: | Yang, H, Li, S, Chen, X.S. | | Deposit date: | 2022-04-28 | | Release date: | 2023-01-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G.
Nat Commun, 13, 2022
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6P7M
 | | Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (1:2 complex) | | Descriptor: | Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ... | | Authors: | Knott, G.J, Liu, J.J, Doudna, J.A. | | Deposit date: | 2019-06-06 | | Release date: | 2019-08-21 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
Elife, 8, 2019
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6P7N
 | | Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (2:2 complex) | | Descriptor: | Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ... | | Authors: | Knott, G.J, Liu, J.J, Doudna, J.A. | | Deposit date: | 2019-06-06 | | Release date: | 2019-08-21 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
Elife, 8, 2019
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5FW3
 | | Crystal structure of SpCas9 variant VRER bound to sgRNA and TGCG PAM target DNA | | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | | Authors: | Anders, C, Bargsten, K, Jinek, M. | | Deposit date: | 2016-02-11 | | Release date: | 2016-06-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
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3S8U
 | | Crystal structure of a 2-azido-adenine-modified RNA | | Descriptor: | Ecoli 23 S rRNA Sarcin Ricin loop | | Authors: | Ennifar, E, Micura, R. | | Deposit date: | 2011-05-31 | | Release date: | 2012-04-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | 2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
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1RLG
 | | Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex | | Descriptor: | 25-MER, 50S ribosomal protein L7Ae | | Authors: | Moore, T, Zhang, Y, Fenley, M.O, Li, H. | | Deposit date: | 2003-11-25 | | Release date: | 2004-06-01 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular Basis of Box C/D RNA-Protein Interactions; Cocrystal Structure of Archaeal L7Ae and a Box C/D RNA.
STRUCTURE, 12, 2004
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5FW2
 | | Crystal structure of SpCas9 variant EQR bound to sgRNA and TGAG PAM target DNA | | Descriptor: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, NON-TARGET DNA STRAND, ... | | Authors: | Anders, C, Bargsten, K, Jinek, M. | | Deposit date: | 2016-02-11 | | Release date: | 2016-06-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.676 Å) | | Cite: | Structural Plasticity of Pam Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.
Mol.Cell, 61, 2016
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4J37
 | | Crystal structure of the catalytic domain of human Pus1 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... | | Authors: | Czudnochowski, N, Finer-Moore, J.S, Stroud, R.M. | | Deposit date: | 2013-02-05 | | Release date: | 2013-06-05 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities.
J.Mol.Biol., 425, 2013
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5APM
 | | Multiple capsid-stabilizing protein-RNA and protein-protein interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis | | Descriptor: | VP0, VP1, VP3 | | Authors: | Shakeel, S, Westerhuis, B.M, Domanska, A, Koning, R.I, Matadeen, R, Koster, A.J, Bakker, A.Q, Beaumont, T, Wolthers, K.C, Butcher, S.J. | | Deposit date: | 2015-09-17 | | Release date: | 2016-07-27 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Multiple Capsid-Stabilizing Interactions Revealed in a High-Resolution Structure of an Emerging Picornavirus Causing Neonatal Sepsis
Nat.Commun., 7, 2016
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7ODN
 | | Crystal structure of TD1-mebendazole complex | | Descriptor: | CHLORIDE ION, Designed Ankyrin Repeat Protein (DARPIN) D1, GLYCEROL, ... | | Authors: | Oliva, M.A, Bonato, F, Diaz, J.F. | | Deposit date: | 2021-04-30 | | Release date: | 2022-04-06 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Effect of Clinically Used Microtubule Targeting Drugs on Viral Infection and Transport Function.
Int J Mol Sci, 23, 2022
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3R9W
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5FSH
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6EVK
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8B8B
 | | Multimerization domain of Munia virus 1 phosphoprotein | | Descriptor: | Munia Bornavirus 1 phosphoprotein, NITRATE ION | | Authors: | Chenavier, F, Tarbouriech, N, Bourhis, J.M, Tomonaga, K, Horie, M, Crepin, T. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-23 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing.
Viruses, 14, 2022
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3S24
 | | Crystal structure of human mRNA guanylyltransferase | | Descriptor: | SULFATE ION, mRNA-capping enzyme | | Authors: | Das, K, Chu, C, Thyminski, J.R, Bauman, J.D, Guan, R, Qiu, W, Montelione, G.T, Arnold, E, Shatkin, A.J. | | Deposit date: | 2011-05-16 | | Release date: | 2011-06-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.0137 Å) | | Cite: | Structure of the guanylyltransferase domain of human mRNA capping enzyme.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3S7C
 | | Crystal structure of a 2'-azido-uridine-modified RNA | | Descriptor: | Ecoli 23 S rRNA Sarcin Ricin loop | | Authors: | Ennifar, E, Micura, R. | | Deposit date: | 2011-05-26 | | Release date: | 2012-04-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | 2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
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3MEI
 | | Regulatory motif from the thymidylate synthase mRNA | | Descriptor: | MAGNESIUM ION, RNA (5'-R(*CP*CP*GP*CP*CP*GP*CP*GP*CP*CP*AP*(5BU)P*GP*CP*CP*UP*GP*UP*GP*GP*CP*GP*G)-3') | | Authors: | Dibrov, S, McLean, J, Hermann, T. | | Deposit date: | 2010-03-31 | | Release date: | 2011-01-26 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.968 Å) | | Cite: | Structure of an RNA dimer of a regulatory element from human thymidylate synthase mRNA.
Acta Crystallogr.,Sect.D, 67, 2011
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5E02
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