4J37

Crystal structure of the catalytic domain of human Pus1

Summary for 4J37

Entry DOI	10.2210/pdb4j37/pdb
Related	4IQM 4ITS
Descriptor	tRNA pseudouridine synthase A, mitochondrial, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	beta sheet, pseudouridine synthase, rna binding protein, trna, pre-trna, steroid receptor rna activator, u2 snrna, isomerase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	38240.01
Authors	Czudnochowski, N.,Finer-Moore, J.S.,Stroud, R.M. (deposition date: 2013-02-05, release date: 2013-06-05, Last modification date: 2023-09-20)
Primary citation	Czudnochowski, N.,Wang, A.L.,Finer-Moore, J.,Stroud, R.M. In Human Pseudouridine Synthase 1 (hPus1), a C-Terminal Helical Insert Blocks tRNA from Binding in the Same Orientation as in the Pus1 Bacterial Homologue TruA, Consistent with Their Different Target Selectivities. J.Mol.Biol., 425:3875-3887, 2013 Cited by PubMed: 23707380 DOI: 10.1016/j.jmb.2013.05.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation