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2OIN
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crystal structure of HCV NS3-4A R155K mutant
Descriptor: NS4A peptide, Polyprotein, ZINC ION
Authors:Wei, Y.
Deposit date:2007-01-11
Release date:2007-06-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Phenotypic and structural analyses of hepatitis C virus NS3 protease Arg155 variants: sensitivity to telaprevir (VX-950) and interferon alpha.
J.Biol.Chem., 282, 2007
2OIP
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Crystal Structure of the S290G Active Site Mutant of TS-DHFR from Cryptosporidium hominis
Descriptor: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Chain A, ...
Authors:Martucci, W.E, Vargo, M.A.
Deposit date:2007-01-11
Release date:2007-07-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nonconserved residues Ala287 and Ser290 of the Cryptosporidium hominis thymidylate synthase domain facilitate its rapid rate of catalysis
Biochemistry, 46, 2007
2OIQ
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Crystal Structure of chicken c-Src kinase domain in complex with the cancer drug imatinib.
Descriptor: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src
Authors:Seeliger, M.A, Nagar, B, Frank, F, Cao, X, Henderson, M.N, Kuriyan, J.
Deposit date:2007-01-11
Release date:2007-03-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:c-Src Binds to the Cancer Drug Imatinib with an Inactive Abl/c-Kit Conformation and a Distributed Thermodynamic Penalty.
Structure, 15, 2007
2OIT
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Crystal Structure of the N-terminal Domain of the Human Proto-oncogene Nup214/CAN
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoporin 214kDa
Authors:Napetschnig, J, Blobel, G, Hoelz, A.
Deposit date:2007-01-11
Release date:2007-02-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OIU
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L1 Ribozyme Ligase circular adduct
Descriptor: L1 Ribozyme RNA Ligase, MAGNESIUM ION
Authors:Robertson, M.P, Scott, W.G.
Deposit date:2007-01-11
Release date:2007-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structural basis of ribozyme-catalyzed RNA assembly.
Science, 315, 2007
2OIV
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Structural Analysis of Xanthomonas XopD Provides Insights Into Substrate Specificity of Ubiquitin-like Protein Proteases
Descriptor: PHOSPHATE ION, Xanthomonas outer protein D
Authors:Chosed, R, Tomchick, D.R, Brautigam, C.A, Machius, M, Orth, K.
Deposit date:2007-01-11
Release date:2007-05-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases.
J.Biol.Chem., 282, 2007
2OIW
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The structure of a predicted thioesterase from Bacillus stearothermophilus
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, putative 4-hydroxybenzoyl-CoA thioesterase
Authors:Cuff, M.E, Li, H, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-01-11
Release date:2007-02-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of a predicted thioesterase from Bacillus stearothermophilus
TO BE PUBLISHED
2OIX
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Xanthomonas XopD C470A Mutant
Descriptor: Xanthomonas outer protein D
Authors:Chosed, R, Tomchick, D.R, Brautigam, C.A, Machius, M, Orth, K.
Deposit date:2007-01-11
Release date:2007-05-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases.
J.Biol.Chem., 282, 2007
2OIY
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Crystal structure of the duplex form of the HIV-1(LAI) RNA dimerization initiation site
Descriptor: 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*AP*GP*CP*GP*CP*GP*CP*AP*CP*GP*GP*CP*AP*AP*G)-3', MAGNESIUM ION, POTASSIUM ION
Authors:Ennifar, E, Walter, P, Dumas, P.
Deposit date:2007-01-12
Release date:2007-12-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cation-dependent cleavage of the duplex form of the subtype-B HIV-1 RNA dimerization initiation site.
Nucleic Acids Res., 38, 2010
2OIZ
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Crystal Structure of the Tryptamine-Derived (Indol-3-Acetamide)-TTQ Adduct of Aromatic Amine Dehydrogenase
Descriptor: 2-(1H-INDOL-3-YL)ACETAMIDE, Aromatic amine dehydrogenase, large subunit, ...
Authors:Roujeinikova, A, Leys, D.
Deposit date:2007-01-12
Release date:2007-04-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:New insights into the reductive half-reaction mechanism of aromatic amine dehydrogenase revealed by reaction with carbinolamine substrates.
J.Biol.Chem., 282, 2007
2OJ0
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Crystal structure of the duplex form of the HIV-1(LAI) RNA dimerization initiation site MN soaked
Descriptor: 5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*AP*GP*CP*GP*CP*GP*CP*AP*CP*GP*GP*CP*AP*AP*G)-3', MANGANESE (II) ION, POTASSIUM ION, ...
Authors:Ennifar, E, Walter, P, Dumas, P.
Deposit date:2007-01-12
Release date:2007-12-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cation-dependent cleavage of the duplex form of the subtype-B HIV-1 RNA dimerization initiation site.
Nucleic Acids Res., 38, 2010
2OJ1
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Disulfide-linked dimer of azurin N42C/M64E double mutant
Descriptor: Azurin, COPPER (II) ION
Authors:de Jongh, T.E, Hoffmann, M, Einsle, O, Cavazzini, D, Rossi, G.L, Ubbink, M, Canters, G.W.
Deposit date:2007-01-12
Release date:2007-11-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Inter- and intramolecular electron transfer in modified azurin dimers
Eur.J.Inorg.Chem., 2007, 2007
2OJ2
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NMR Structure Analysis of the Hematopoetic Cell Kinase SH3 Domain complexed with an artificial high affinity ligand (PD1)
Descriptor: Hematopoetic Cell Kinase, SH3 domain, artificial peptide PD1
Authors:Schmidt, H, Hoffmann, S, Tran, T, Stoldt, M, Stangler, T, Wiesehan, K, Willbold, D.
Deposit date:2007-01-12
Release date:2007-01-30
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of a Hck SH3 Domain Ligand Complex Reveals Novel Interaction Modes
J.Mol.Biol., 365, 2007
2OJ3
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Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+)
Descriptor: COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ...
Authors:Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
Deposit date:2007-01-12
Release date:2007-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
2OJ4
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Crystal structure of RGS3 RGS domain
Descriptor: Regulator of G-protein signaling 3
Authors:Boura, E, Obsil, T.
Deposit date:2007-01-12
Release date:2007-01-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3).
J.Struct.Biol., 170, 2010
2OJ5
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BU of 2oj5 by Molmil
Crystal Structure of Reovirus T3D Attachment Protein Sigma1 head domain wild-type at 1.75 A resolution
Descriptor: GLYCEROL, MAGNESIUM ION, Viral attachment protein sigma 1
Authors:Stehle, T, Schelling, P, Kirchner, E, Dermody, T.S.
Deposit date:2007-01-12
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The Reovirus Sigma1 Aspartic Acid Sandwich: A TRIMERIZATION MOTIF POISED FOR CONFORMATIONAL CHANGE.
J.Biol.Chem., 282, 2007
2OJ6
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Crystal Structure of Reovirus T3D Attachment Protein Sigma1 head domain D345N mutant
Descriptor: MAGNESIUM ION, Viral attachment protein sigma 1
Authors:Stehle, T, Kirchner, E, Dermody, T.S.
Deposit date:2007-01-12
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Reovirus Sigma1 Aspartic Acid Sandwich: A TRIMERIZATION MOTIF POISED FOR CONFORMATIONAL CHANGE.
J.Biol.Chem., 282, 2007
2OJ7
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NMR structure of the UGUU tetraloop of Duck Epsilon apical stem loop
Descriptor: 5'-R(P*GP*CP*UP*GP*UP*UP*GP*U)-3'
Authors:Girard, F.C, Ottink, O.M, Ampt, K.A.M, Tessari, M, Wijmenga, S.S.
Deposit date:2007-01-12
Release date:2007-05-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Thermodynamics and NMR studies on Duck, Heron and Human HBV encapsidation signals.
Nucleic Acids Res., 35, 2007
2OJ8
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NMR structure of the UGUU tetraloop of Duck Epsilon apical stem loop of the Hepatitis B virus
Descriptor: 5'-R(P*GP*CP*UP*GP*UP*UP*GP*U)-3'
Authors:Girard, F.C, Ottink, O.M, Ampt, K.A.M, Tessari, M, Wijmenga, S.S.
Deposit date:2007-01-12
Release date:2007-05-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Thermodynamics and NMR studies on Duck, Heron and Human HBV encapsidation signals.
Nucleic Acids Res., 35, 2007
2OJ9
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Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor
Descriptor: 3-[5-(1H-IMIDAZOL-1-YL)-7-METHYL-1H-BENZIMIDAZOL-2-YL]-4-[(PYRIDIN-2-YLMETHYL)AMINO]PYRIDIN-2(1H)-ONE, Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen)
Authors:Sack, J.S, Jacobson, B.L.
Deposit date:2007-01-12
Release date:2007-05-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery and initial SAR of 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-ones as inhibitors of insulin-like growth factor 1-receptor (IGF-1R).
Bioorg.Med.Chem.Lett., 17, 2007
2OJE
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Mycoplasma arthritidis-derived mitogen complexed with class II MHC molecule HLA-DR1/HA complex in the presence of EDTA
Descriptor: HLA class II histocompatibility antigen, DR alpha chain precursor, DRB1-1 beta chain precursor, ...
Authors:Li, H, Zhao, Y, Guo, Y, Li, Z, Eisele, L, Mourad, W.
Deposit date:2007-01-12
Release date:2007-01-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Zinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen.
J.Biol.Chem., 282, 2007
2OJF
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Crystal structure of Protein Kinase A in complex with Pyridine-Pyrazolopyridine based inhibitors
Descriptor: (2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE, Inhibitory peptide, cAMP-dependent protein kinase, ...
Authors:Stoll, V.S.
Deposit date:2007-01-12
Release date:2007-03-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design and synthesis of pyridine-pyrazolopyridine-based inhibitors of protein kinase B/Akt.
Bioorg.Med.Chem., 15, 2007
2OJG
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Crystal structure of ERK2 in complex with N,N-dimethyl-4-(4-phenyl-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
Descriptor: Mitogen-activated protein kinase 1, N,N-DIMETHYL-4-(4-PHENYL-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE, SULFATE ION
Authors:Xie, X, Jacobs, M.D.
Deposit date:2007-01-12
Release date:2007-02-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors.
J.Med.Chem., 50, 2007
2OJH
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The structure of putative TolB from Agrobacterium tumefaciens
Descriptor: ACETIC ACID, Uncharacterized protein Atu1656/AGR_C_3050
Authors:Cuff, M.E, Xu, X, Gu, J, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-01-12
Release date:2007-02-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The structure of putative TolB from Agrobacterium tumefaciens
TO BE PUBLISHED
2OJI
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Crystal structure of ERK2 in complex with N-benzyl-4-(4-(3-chlorophenyl)-1H-pyrazol-3-yl)-1H-pyrrole-2-carboxamide
Descriptor: Mitogen-activated protein kinase 1, N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE, SULFATE ION
Authors:Xie, X, Jacobs, M.D.
Deposit date:2007-01-12
Release date:2007-02-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors.
J.Med.Chem., 50, 2007

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