2OJ2

NMR Structure Analysis of the Hematopoetic Cell Kinase SH3 Domain complexed with an artificial high affinity ligand (PD1)

Replaces:  2A4Y

Summary for 2OJ2

• Entry DOI: 10.2210/pdb2oj2/pdb
• NMR Information: BMRB: 6581
• Descriptor: Hematopoetic Cell Kinase, SH3 domain, artificial peptide PD1 (2 entities in total)
• Functional Keywords: human hck; sh3; src-type tyrosine kinase; nmr, signaling protein, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform p59-HCK: Membrane; Lipid-anchor. Isoform p60-HCK: Membrane; Lipid-anchor: P08631
• Total number of polymer chains: 2
• Total formula weight: 10872.02

Authors

Schmidt, H.,Hoffmann, S.,Tran, T.,Stoldt, M.,Stangler, T.,Wiesehan, K.,Willbold, D. (deposition date: 2007-01-12, release date: 2007-01-30, Last modification date: 2023-12-27)

• Primary citation: Schmidt, H.,Hoffmann, S.,Tran, T.,Stoldt, M.,Stangler, T.,Wiesehan, K.,Willbold, D.; Solution Structure of a Hck SH3 Domain Ligand Complex Reveals Novel Interaction Modes; J.Mol.Biol., 365:1517-1532, 2007; PubMed: 17141806; DOI: 10.1016/j.jmb.2006.11.013

Experimental method

SOLUTION NMR