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2O1F
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Natural Occuring Mutation of Human ABO(H) galactosyltransferase: GTB/M214R
Descriptor: ABO glycosyltransferase, MERCURY (II) ION
Authors:Letts, J.A, Borisova, S.N, Evans, S.V.
Deposit date:2006-11-28
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural effects of naturally occurring human blood group B galactosyltransferase mutations adjacent to the DXD motif.
J.Biol.Chem., 282, 2007
2O1G
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Natural occurring mutant of Human ABO(H) Galactosyltransferase: GTB/M214T
Descriptor: ABO glycosyltransferase, MERCURY (II) ION
Authors:Letts, J.A, Borisova, S.N, Evans, S.V.
Deposit date:2006-11-28
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structural effects of naturally occurring human blood group B galactosyltransferase mutations adjacent to the DXD motif.
J.Biol.Chem., 282, 2007
2O1H
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Naturally occurring mutation of Humna ABO(H) Galactosyltransferase in complex with UDP: GTB/M214T_UDP
Descriptor: ABO glycosyltransferase, MANGANESE (II) ION, MERCURY (II) ION, ...
Authors:Letts, J.A, Borisova, S.N, Evans, S.V.
Deposit date:2006-11-28
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural effects of naturally occurring human blood group B galactosyltransferase mutations adjacent to the DXD motif.
J.Biol.Chem., 282, 2007
2O1I
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RH(BPY)2CHRYSI complexed to mismatched DNA
Descriptor: 5'-D(*CP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*G)-3', bis(2,2'-bipyridine-kappa~2~N~1~,N~1'~)[chrysene-5,6-diiminato(2-)-kappa~2~N,N']rhodium(4+)
Authors:Pierre, V.C, Kaiser, J.T, Barton, J.K.
Deposit date:2006-11-28
Release date:2007-01-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Insights into finding a mismatch through the structure of a mispaired DNA bound by a rhodium intercalator.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2O1J
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Structure of the extended diarrhea-inducing domain of rotavirus enterotoxigenic protein NSP4
Descriptor: CALCIUM ION, Nonstructural protein NSP4
Authors:Suguna, K, Durga Rao, C, Deepa, R.
Deposit date:2006-11-29
Release date:2006-12-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the extended diarrhea-inducing domain of rotavirus enterotoxigenic protein NSP4
TO BE PUBLISHED
2O1K
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Structure of the extended diarrhea-inducing domain of rotavirus enterotoxigenic protein NSP4
Descriptor: CALCIUM ION, Non-structural glycoprotein NSP4
Authors:Deepa, R, Suguna, K, Durga Rao, C.
Deposit date:2006-11-29
Release date:2006-12-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structure of the extended diarrhea-inducing domain of rotavirus enterotoxigenic protein
TO BE PUBLISHED
2O1L
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Structure of a complex of C-terminal lobe of bovine lactoferrin with disaccharide at 1.97 A resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
Authors:Singh, N, Sharma, S, Perbandt, M, Kaur, P, Betzel, C, Singh, T.P.
Deposit date:2006-11-29
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of a complex of C-terminal lobe of bovine lactoferrin with disaccharide at 1.97 A resolution
To be Published
2O1M
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Crystal structure of the probable amino-acid ABC transporter extracellular-binding protein ytmK from Bacillus subtilis. Northeast Structural Genomics Consortium target SR572
Descriptor: Probable amino-acid ABC transporter extracellular-binding protein ytmK, SULFATE ION
Authors:Kuzin, A.P, Su, M, Seetharaman, J, Chen, C.X, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-11-29
Release date:2006-12-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the probable amino-acid ABC transporter extracellular-binding protein ytmK from Bacillus subtilis. Northeast Structural Genomics Consortium target SR572.
To be Published
2O1N
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Crystal structure of a complex of phospholipase A2 with a peptide Ala-Ile-Ala-Ser at 2.8 A resolution
Descriptor: Ala-Ile-Ala-Ser peptide, Phospholipase A2 VRV-PL-VIIIa
Authors:Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P.
Deposit date:2006-11-29
Release date:2006-12-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a complex of phospholipase A2 with a peptide Ala-Ile-Ala-Ser at 2.8 A resolution
To be Published
2O1O
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Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with risedronate.
Descriptor: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, MAGNESIUM ION, Putative farnesyl pyrophosphate synthase
Authors:Chruszcz, M, Artz, J.D, Dong, A, Dunford, J, Lew, J, Zhao, Y, Kozieradski, I, Kavanaugh, K.L, Oppermann, U, Sundstrom, M, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Minor, W, Structural Genomics Consortium (SGC)
Deposit date:2006-11-29
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis
Chem.Biol., 15, 2008
2O1P
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Structure of yeast Poly(A) Polymerase in a somewhat closed state
Descriptor: Poly(A) polymerase
Authors:Bohm, A, Balbo, P, Toth, J.
Deposit date:2006-11-29
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
2O1Q
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CRYSTAL STRUCTURE OF A PUTATIVE ACETYLACETONE DIOXYGENASE (MPE_A3659) FROM METHYLIBIUM PETROLEIPHILUM PM1 AT 1.50 A RESOLUTION
Descriptor: ACETATE ION, CHLORIDE ION, TETRAETHYLENE GLYCOL, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2006-11-29
Release date:2007-01-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of putative acetyl/propionyl-CoA carboxylase, alpha subunit (ZP_00243239.1) from Rubrivivax gelatinosus PM1 (Methylobium petroleophilum PM1) at 1.50 A resolution
To be published
2O1S
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1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Escherichia coli
Descriptor: 1-deoxy-D-xylulose-5-phosphate synthase, DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Xiang, S, Usunow, G, Lange, G, Busch, M, Tong, L.
Deposit date:2006-11-29
Release date:2006-12-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of 1-Deoxy-D-xylulose 5-Phosphate Synthase, a Crucial Enzyme for Isoprenoids Biosynthesis.
J.Biol.Chem., 282, 2007
2O1T
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Structure of Middle plus C-terminal domains (M+C) of GRP94
Descriptor: Endoplasmin
Authors:Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T.
Deposit date:2006-11-29
Release date:2007-10-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
2O1U
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Structure of full length GRP94 with AMP-PNP bound
Descriptor: Endoplasmin, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T.
Deposit date:2006-11-29
Release date:2007-10-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
2O1V
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Structure of full length GRP94 with ADP bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION
Authors:Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T.
Deposit date:2006-11-29
Release date:2007-10-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
2O1W
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Structure of N-terminal plus middle domains (N+M) of GRP94
Descriptor: Endoplasmin
Authors:Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T.
Deposit date:2006-11-29
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
2O1X
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1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Deinococcus radiodurans
Descriptor: 1-deoxy-D-xylulose-5-phosphate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
Authors:Xiang, S, Usunow, G, Lange, G, Busch, M, Tong, L.
Deposit date:2006-11-29
Release date:2006-12-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of 1-Deoxy-D-xylulose 5-Phosphate Synthase, a Crucial Enzyme for Isoprenoids Biosynthesis.
J.Biol.Chem., 282, 2007
2O1Y
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Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand
Descriptor: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-X
Authors:Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W.
Deposit date:2006-11-29
Release date:2007-02-27
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2O1Z
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Plasmodium vivax Ribonucleotide Reductase Subunit R2 (Pv086155)
Descriptor: FE (III) ION, Ribonucleotide Reductase Subunit R2, UNKNOWN ATOM OR ION
Authors:Dong, A, Tempel, W, Qiu, W, Lew, J, Wernimont, A.K, Lin, Y.H, Hassanali, A, Melone, M, Zhao, Y, Nordlund, P, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Artz, J.D, Amani, M, Structural Genomics Consortium (SGC)
Deposit date:2006-11-29
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Plasmodium vivax Ribonucleotide Reductase Subunit R2 (Pv086155)
To be Published
2O20
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Crystal structure of transcription regulator CcpA of Lactococcus lactis
Descriptor: CHLORIDE ION, Catabolite control protein A, SULFATE ION
Authors:Loll, B, Kowalczyk, M, Alings, C, Chieduch, A, Bardowski, J, Saenger, W, Biesiadka, J.
Deposit date:2006-11-29
Release date:2007-03-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the transcription regulator CcpA from Lactococcus lactis
Acta Crystallogr.,Sect.D, 63, 2007
2O21
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Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand
Descriptor: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2
Authors:Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W.
Deposit date:2006-11-29
Release date:2007-02-27
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2O22
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Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand
Descriptor: Apoptosis regulator Bcl-2, N-[(4-{[1,1-dimethyl-2-(phenylthio)ethyl]amino}-3-nitrophenyl)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamide
Authors:Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W.
Deposit date:2006-11-29
Release date:2007-02-27
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2O23
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The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A
Descriptor: GLYCEROL, HADH2 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kavanagh, K.L, Shafqat, N, Scholer, K, Debreczeni, J, Zschocke, J, von Delft, F, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2006-11-29
Release date:2006-12-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A
To be Published
2O24
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Spectroscopic and Structural Study of the Heterotropic Linkage between Halide and Proton Ion Binding to Gfp Proteins: E2(GFP)-Cl Complex
Descriptor: CHLORIDE ION, Green fluorescent protein
Authors:Garau, G.
Deposit date:2006-11-29
Release date:2007-05-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Spectroscopic and Structural Study of Proton and Halide Ion Cooperative Binding to GFP.
Biophys.J., 93, 2007

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