3LWO
 
 | | Structure of H/ACA RNP bound to a substrate RNA containing 5BrU | | Descriptor: | 5'-R(*GP*AP*GP*CP*GP*(5BU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, H/ACA RNA, ... | | Authors: | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | | Deposit date: | 2010-02-24 | | Release date: | 2010-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.855 Å) | | Cite: | Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study.
J.Mol.Biol., 401, 2010
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3LWP
 | | Structure of H/ACA RNP bound to a substrate RNA containing 5BrdU | | Descriptor: | 5'-R(*GP*AP*GP*CP*GP*(BRU)P*GP*CP*GP*GP*UP*UP*U)-3, 50S ribosomal protein L7Ae, H/ACA RNA, ... | | Authors: | Zhou, J, Liang, B, Lv, C, Yang, W, Li, H. | | Deposit date: | 2010-02-24 | | Release date: | 2010-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Glycosidic bond conformation preference plays a pivotal role in catalysis of RNA pseudouridylation: a combined simulation and structural study.
J.Mol.Biol., 401, 2010
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7SOQ
 | | LaM domain of human LARP1 in complex with AAA RNA | | Descriptor: | Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*A)-3') | | Authors: | Kozlov, G, Gehring, K. | | Deposit date: | 2021-11-01 | | Release date: | 2022-08-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
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7SOR
 | | LaM domain of human LARP1 in complex with AAA RNA | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Isoform 2 of La-related protein 1, ... | | Authors: | Kozlov, G, Gehring, K. | | Deposit date: | 2021-11-01 | | Release date: | 2022-08-03 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Structural basis of 3'-end poly(A) RNA recognition by LARP1.
Nucleic Acids Res., 50, 2022
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6V5C
 | | Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - partially docked state | | Descriptor: | Microprocessor complex subunit DGCR8, Pri-miR-16-2 (66-MER), Ribonuclease 3 | | Authors: | Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y. | | Deposit date: | 2019-12-04 | | Release date: | 2020-04-08 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.
Mol.Cell, 78, 2020
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7SOP
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6V5B
 | | Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - Active state | | Descriptor: | CALCIUM ION, Microprocessor complex subunit DGCR8, Pri-miR-16-2 (78-MER), ... | | Authors: | Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y. | | Deposit date: | 2019-12-04 | | Release date: | 2020-04-08 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA.
Mol.Cell, 78, 2020
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2JEB
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4HT8
 | | Crystal structure of E coli Hfq bound to poly(A) A7 | | Descriptor: | Protein hfq, RNA (5'-R(*AP*AP*AP*AP*AP*AP*A)-3') | | Authors: | Wang, W.W, Wang, L.J. | | Deposit date: | 2012-11-01 | | Release date: | 2013-04-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Hfq-bridged ternary complex is important for translation activation of rpoS by DsrA.
Nucleic Acids Res., 41, 2013
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2JE6
 | | Structure of a 9-subunit archaeal exosome | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, EXOSOME COMPLEX EXONUCLEASE 1, ... | | Authors: | Lorentzen, E, Conti, E. | | Deposit date: | 2007-01-15 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | RNA Channelling by the Archaeal Exosome.
Embo Rep., 8, 2007
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7OFZ
 | | Nontypeable Haemophillus influenzae SapA in complex with double stranded RNA | | Descriptor: | ABC-type transport system, periplasmic component, involved in antimicrobial peptide resistance, ... | | Authors: | Lukacik, P, Owen, C.D, Nettleship, J.E, Bird, L.E, Owens, R.J, Walsh, M.A. | | Deposit date: | 2021-05-05 | | Release date: | 2021-10-27 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.
Plos One, 16, 2021
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5M8I
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4YCP
 | | E. coli dihydrouridine synthase C (DusC) in complex with tRNATrp | | Descriptor: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, SULFATE ION, ... | | Authors: | Byrne, R.T, Jenkins, H.T, Peters, D.T, Whelan, F, Stowell, J, Aziz, N, Kasatsky, P, Rodnina, M.V, Koonin, E.V, Konevega, A.L, Antson, A.A. | | Deposit date: | 2015-02-20 | | Release date: | 2015-04-22 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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8D1V
 | | Cryo-EM structure of guide RNA and target RNA bound Cas7-11 | | Descriptor: | CRISPR RNA (34-MER), CRISPR-associated RAMP family protein, SS target RNA (5'-R(P*AP*GP*CP*UP*UP*GP*GP*UP*UP*CP*AP*AP*AP*GP*AP*AP*CP*G)-3'), ... | | Authors: | Rai, J, Goswami, H, Li, H. | | Deposit date: | 2022-05-27 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | Molecular mechanism of active Cas7-11 in processing CRISPR RNA and interfering target RNA.
Elife, 11, 2022
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5NQI
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6SX0
 | | Specific dsRNA recognition by wild type H7N1 NS1 RNA-binding domain | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Non-structural protein 1, ... | | Authors: | Coste, F, Wacquiez, A, Marc, D, Castaing, B. | | Deposit date: | 2019-09-24 | | Release date: | 2020-10-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
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1IBK
 | | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTIC PAROMOMYCIN | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | Authors: | Ogle, J.M, Brodersen, D.E, Clemons Jr, W.M, Tarry, M.J, Carter, A.P, Ramakrishnan, V. | | Deposit date: | 2001-03-28 | | Release date: | 2001-05-04 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (3.31 Å) | | Cite: | Recognition of cognate transfer RNA by the 30S ribosomal subunit.
Science, 292, 2001
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4TZ0
 | | DEAD-box helicase Mss116 bound to ssRNA and GDP-BeF | | Descriptor: | ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | | Deposit date: | 2014-07-09 | | Release date: | 2014-12-31 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
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4TYY
 | | DEAD-box helicase Mss116 bound to ssRNA and CDP-BeF | | Descriptor: | ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | | Deposit date: | 2014-07-09 | | Release date: | 2014-12-31 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
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4TYW
 | | DEAD-box helicase Mss116 bound to ssRNA and ADP-BeF | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, mitochondrial, ... | | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | | Deposit date: | 2014-07-09 | | Release date: | 2014-12-31 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.197 Å) | | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
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4TZ6
 | | DEAD-box helicase Mss116 bound to ssRNA and UDP-BeF | | Descriptor: | ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | | Deposit date: | 2014-07-09 | | Release date: | 2015-01-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.209 Å) | | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
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5F0S
 | | Crystal structure of C-terminal domain of the human DNA primase large subunit with bound DNA template/RNA primer and manganese ion | | Descriptor: | DNA (5'-D(*GP*CP*CP*GP*CP*CP*AP*AP*CP*AP*TP*A)-3'), DNA primase large subunit, IRON/SULFUR CLUSTER, ... | | Authors: | Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. | | Deposit date: | 2015-11-28 | | Release date: | 2016-03-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.
J.Biol.Chem., 291, 2016
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5WNV
 | | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | | Descriptor: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | | Authors: | DeMirci, H. | | Deposit date: | 2017-08-01 | | Release date: | 2018-02-21 | | Last modified: | 2020-10-21 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation.
Nat. Struct. Mol. Biol., 25, 2018
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7OG0
 | | Nontypeable Haemophillus influenzae SapA in open and closed conformations, in complex with double stranded RNA | | Descriptor: | ABC-type transport system, periplasmic component, involved in antimicrobial peptide resistance, ... | | Authors: | Lukacik, P, Owen, C.D, Nettleship, J.E, Bird, L.E, Owens, R.J, Walsh, M.A. | | Deposit date: | 2021-05-05 | | Release date: | 2021-10-27 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.
Plos One, 16, 2021
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3D2S
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