3H42
 
 | | Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody | | Descriptor: | Fab from LDLR competitive antibody: Heavy chain, Fab from LDLR competitive antibody: Light chain, Proprotein convertase subtilisin/kexin type 9, ... | | Authors: | Piper, D.E, Walker, N.P.C, Romanow, W.G, Thibault, S.T, Tsai, M.M, Yang, E. | | Deposit date: | 2009-04-17 | | Release date: | 2009-05-05 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | From the Cover: A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3H6T
 | | Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and cyclothiazide at 2.25 A resolution | | Descriptor: | ACETATE ION, CACODYLATE ION, CYCLOTHIAZIDE, ... | | Authors: | Hald, H, Gajhede, M, Kastrup, J.S. | | Deposit date: | 2009-04-24 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.
J.Mol.Biol., 391, 2009
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4NZK
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3UCH
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4O1L
 | | Human Adenosine Kinase in complex with inhibitor | | Descriptor: | 5-ethynyl-7-(beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Adenosine kinase, MAGNESIUM ION | | Authors: | Brynda, J, Dostal, J, Pichova, I, Hodcek, M. | | Deposit date: | 2013-12-16 | | Release date: | 2014-11-26 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides
J.Med.Chem., 57, 2014
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3H36
 | | Structure of an uncharacterized domain in polyribonucleotide nucleotidyltransferase from Streptococcus mutans UA159 | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Polyribonucleotide nucleotidyltransferase | | Authors: | Cuff, M.E, Hatzos, C, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-04-15 | | Release date: | 2009-05-12 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of an uncharacterized domain in polyribonucleotide nucleotidyltransferase from Streptococcus mutans UA159
TO BE PUBLISHED
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4O53
 | | Crystal Structure of Trichomonas vaginalis Triosephosphate Isomerase Ile45-Leu mutant (Tvag_497370) | | Descriptor: | SODIUM ION, Triosephosphate isomerase | | Authors: | Lara-Gonzalez, S, Montero-Moran, G.M, Estrella-Hernandez, P, Benitez-Cardoza, C.G, Brieba, L.G. | | Deposit date: | 2013-12-19 | | Release date: | 2014-12-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Engineering mutants with altered dimer-monomer equilibrium reveal the existence of stable monomeric Triosephosphate isomerases
To be Published
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3UJ1
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4O4W
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4O52
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3UCW
 | | Structure of MG2+ bound N-Terminal domain of Calmodulin | | Descriptor: | Calmodulin, MAGNESIUM ION | | Authors: | Senguen, F.T, Grabarek, Z. | | Deposit date: | 2011-10-27 | | Release date: | 2012-08-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | X-ray Structures of Magnesium and Manganese Complexes with the N-Terminal Domain of Calmodulin: Insights into the Mechanism and Specificity of Metal Ion Binding to an EF-Hand.
Biochemistry, 51, 2012
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3GT2
 | | Crystal Structure of the P60 Domain from M. avium paratuberculosis Antigen MAP1272c | | Descriptor: | 1,2-ETHANEDIOL, Putative uncharacterized protein, SULFATE ION | | Authors: | Ramyar, K.X, Lingle, C.K, McWhorter, W.J, Bouyain, S, Bannantine, J.P, Geisbrecht, B.V. | | Deposit date: | 2009-03-27 | | Release date: | 2010-04-07 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal Structures of Two P60-Family Antigens from Mycobacterium Avium Paratuberculosis
To be Published
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4O4V
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4O50
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4O57
 | | Crystal Structure of Trichomonas vaginalis Triosephosphate Isomerase Ile45-Tyr mutant (Tvag_497370) | | Descriptor: | SODIUM ION, Triosephosphate isomerase | | Authors: | Lara-Gonzalez, S, Estrella-Hernandez, P, Montero-Moran, G.M, Benitez-Cardoza, C.G, Brieba, L.G. | | Deposit date: | 2013-12-19 | | Release date: | 2014-12-24 | | Method: | X-RAY DIFFRACTION (1.793 Å) | | Cite: | Engineering mutants with altered dimer-monomer equilibrium reveal the existence of stable monomeric Triosephosphate isomerases
To be Published
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4O54
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3H8G
 | | Bestatin complex structure of leucine aminopeptidase from Pseudomonas putida | | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, BICARBONATE ION, Cytosol aminopeptidase, ... | | Authors: | Kale, A, Dijkstra, B.W, Sonke, T, Thunnissen, A.M.W.H. | | Deposit date: | 2009-04-29 | | Release date: | 2010-04-14 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of the leucine aminopeptidase from Pseudomonas putida reveals the molecular basis for its enantioselectivity and broad substrate specificity.
J.Mol.Biol., 398, 2010
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4O7S
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4O86
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3H7T
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3H0G
 | | RNA Polymerase II from Schizosaccharomyces pombe | | Descriptor: | DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D. | | Deposit date: | 2009-04-09 | | Release date: | 2009-08-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.65 Å) | | Cite: | Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3H7O
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3H8W
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3UWT
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4O82
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