4HME
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![BU of 4hme by Molmil](/molmil-images/mine/4hme) | Crystal structure of cold-adapted chitinase from Moritella marina with a reaction product - NAG2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase 60, GLYCEROL, ... | Authors: | Malecki, P.H, Vorgias, C.E, Raczynska, J.E, Rypniewski, W. | Deposit date: | 2012-10-18 | Release date: | 2013-05-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium Acta Crystallogr.,Sect.D, 69, 2013
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4HU0
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4HK2
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![BU of 4hk2 by Molmil](/molmil-images/mine/4hk2) | U7Ub25.2540 | Descriptor: | SULFATE ION, Ubiquitin | Authors: | Murray, J.M, Rouge, L. | Deposit date: | 2012-10-14 | Release date: | 2012-11-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization to be published
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4HOV
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![BU of 4hov by Molmil](/molmil-images/mine/4hov) | DypB N246A in complex with manganese | Descriptor: | CHLORIDE ION, DypB, FORMIC ACID, ... | Authors: | Grigg, J.C, Singh, R, Eltis, L.D, Murphy, M.E.P. | Deposit date: | 2012-10-22 | Release date: | 2013-01-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Improved Manganese-Oxidizing Activity of DypB, a Peroxidase from a Lignolytic Bacterium. Acs Chem.Biol., 8, 2013
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2RKL
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![BU of 2rkl by Molmil](/molmil-images/mine/2rkl) | Crystal Structure of S.cerevisiae Vta1 C-terminal domain | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Vacuolar protein sorting-associated protein VTA1 | Authors: | Xiao, J, Xia, H, Zhou, J, Xu, Z. | Deposit date: | 2007-10-16 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of vta1 function in the multivesicular body sorting pathway. Dev.Cell, 14, 2008
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4HR3
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3FJ5
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![BU of 3fj5 by Molmil](/molmil-images/mine/3fj5) | Crystal structure of the c-src-SH3 domain | Descriptor: | ACETATE ION, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... | Authors: | Camara-Artigas, A. | Deposit date: | 2008-12-14 | Release date: | 2009-03-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding Febs Lett., 583, 2009
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4HOG
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![BU of 4hog by Molmil](/molmil-images/mine/4hog) | Candida glabrata dihydrofolate reductase complexed with NADPH and 5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111H) | Descriptor: | 5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, CHLORIDE ION, Dihydrofolate Reductase, ... | Authors: | Paulsen, J.L, Anderson, A.C. | Deposit date: | 2012-10-22 | Release date: | 2014-03-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata. J.Med.Chem., 57, 2014
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2RIZ
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3FN2
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![BU of 3fn2 by Molmil](/molmil-images/mine/3fn2) | Crystal structure of a putative sensor histidine kinase domain from Clostridium symbiosum ATCC 14940 | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, POTASSIUM ION, ... | Authors: | Cuff, M.E, Tesar, C, Freeman, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-12-23 | Release date: | 2009-01-27 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure of a putative sensor histidine kinase domain from Clostridium symbiosum ATCC 14940 TO BE PUBLISHED
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3CI0
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4HRN
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4HHV
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![BU of 4hhv by Molmil](/molmil-images/mine/4hhv) | Crystal structure of ceramide transfer protein pleckstrin homology domain | Descriptor: | ACETATE ION, CHLORIDE ION, Collagen type IV alpha-3-binding protein, ... | Authors: | Prashek, J, Truong, T, Yao, X. | Deposit date: | 2012-10-10 | Release date: | 2013-11-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal Structure of the Pleckstrin Homology Domain from the Ceramide Transfer Protein: Implications for Conformational Change upon Ligand Binding. Plos One, 8, 2013
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4HN4
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![BU of 4hn4 by Molmil](/molmil-images/mine/4hn4) | Tryptophan synthase in complex with alpha aminoacrylate E(A-A) form and the F9 inhibitor in the alpha site | Descriptor: | 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, BICINE, ... | Authors: | Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. | Deposit date: | 2012-10-18 | Release date: | 2013-12-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states. Biochemistry, 52, 2013
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4HRL
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4HU7
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![BU of 4hu7 by Molmil](/molmil-images/mine/4hu7) | E. coli thioredoxin variant with Pro76 as single proline residue | Descriptor: | COPPER (II) ION, SODIUM ION, Thioredoxin-1 | Authors: | Glockshuber, R, Scharer, M.A, Capitani, G, Rubini, M. | Deposit date: | 2012-11-02 | Release date: | 2013-05-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | (4R)- and (4S)-Fluoroproline in the Conserved cis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering. Chembiochem, 14, 2013
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4HNK
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![BU of 4hnk by Molmil](/molmil-images/mine/4hnk) | Crystal structure of an Enzyme | Descriptor: | ATP-dependent Clp protease proteolytic subunit, GLYCEROL | Authors: | El Bakkouri, M, Calmettes, C, Wernimont, A.K, Houry, W.A, Hui, R, Structural Genomics Consortium (SGC) | Deposit date: | 2012-10-19 | Release date: | 2012-12-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural Insights into the Inactive Subunit of the Apicoplast-localized Caseinolytic Protease Complex of Plasmodium falciparum. J.Biol.Chem., 288, 2013
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4HI9
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![BU of 4hi9 by Molmil](/molmil-images/mine/4hi9) | 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974 | Descriptor: | IODIDE ION, Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ... | Authors: | Stiegler, A.L, Jakoncic, J, Stojanoff, V, Chiswell, B.P, Calderwood, D.A, Boggon, T.J. | Deposit date: | 2012-10-11 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.203 Å) | Cite: | 1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974 To be Published
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4HK3
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![BU of 4hk3 by Molmil](/molmil-images/mine/4hk3) | I2 Fab (unbound) from CH65-CH67 Lineage | Descriptor: | I2 heavy chain, I2 light chain | Authors: | Schmidt, A.G, Harrison, S.C. | Deposit date: | 2012-10-14 | Release date: | 2012-11-21 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
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4HKG
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![BU of 4hkg by Molmil](/molmil-images/mine/4hkg) | Crystal Structure of Free-Standing Peptidyl Carrier Protein from Uncharacterized Acinetobacter baumannii Secondary Metabolic Pathway | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Allen, C.L, Gulick, A.M. | Deposit date: | 2012-10-15 | Release date: | 2013-10-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.3002 Å) | Cite: | Structural and bioinformatic characterization of an Acinetobacter baumannii type II carrier protein. Acta Crystallogr. D Biol. Crystallogr., 70, 2014
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4HKP
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![BU of 4hkp by Molmil](/molmil-images/mine/4hkp) | Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with CMP-N3-oxide | Descriptor: | 5-hydroxycytidine 5'-(dihydrogen phosphate), GLYCEROL, N-hydroxycytidine 5'-(dihydrogen phosphate), ... | Authors: | To, T.K, Kotra, L.P, Pai, E.F. | Deposit date: | 2012-10-15 | Release date: | 2012-11-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist. J.Med.Chem., 55, 2012
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4HMJ
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![BU of 4hmj by Molmil](/molmil-images/mine/4hmj) | Crystal structure of Staphylococcal nuclease variant Delta+PHS L36D at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Robinson, A.C, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. | Deposit date: | 2012-10-18 | Release date: | 2012-10-31 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS L36D at cryogenic temperature To be Published
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4HLB
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4HNO
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![BU of 4hno by Molmil](/molmil-images/mine/4hno) | High resolution crystal structure of DNA Apurinic/apyrimidinic (AP) endonuclease IV Nfo from Thermatoga maritima | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... | Authors: | Shin, D.S, Hosfield, D.J, Arvai, A.S, Tsutakawa, S.E, Tainer, J.A. | Deposit date: | 2012-10-20 | Release date: | 2013-01-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (0.9194 Å) | Cite: | Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes. J.Biol.Chem., 288, 2013
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3D27
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![BU of 3d27 by Molmil](/molmil-images/mine/3d27) | E. coli methionine aminopeptidase with Fe inhibitor W29 | Descriptor: | 4-(3-ethylthiophen-2-yl)benzene-1,2-diol, MANGANESE (II) ION, Methionine aminopeptidase | Authors: | Ye, Q.Z, Chai, S, He, H.Z. | Deposit date: | 2008-05-07 | Release date: | 2008-08-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity. J.Med.Chem., 51, 2008
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