5UXV
 
 | |
5UXW
 | |
5U8M
 | |
3I5A
 | | Crystal structure of full-length WpsR from Pseudomonas syringae | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Response regulator/GGDEF domain protein, STRONTIUM ION | | Authors: | Navarro, M.V.A.S, De, N, Sondermann, H. | | Deposit date: | 2009-07-03 | | Release date: | 2009-08-18 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.796 Å) | | Cite: | Determinants for the activation and autoinhibition of the diguanylate cyclase response regulator WspR.
J.Mol.Biol., 393, 2009
|
|
5VFA
 | | RitR Mutant - C128D | | Descriptor: | Response regulator | | Authors: | Han, L, Silvaggi, N.R. | | Deposit date: | 2017-04-07 | | Release date: | 2018-04-11 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.452 Å) | | Cite: | RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
|
|
3HZH
 | | Crystal structure of the CheX-CheY-BeF3-Mg+2 complex from Borrelia burgdorferi | | Descriptor: | Chemotaxis operon protein (CheX), Chemotaxis response regulator (CheY-3), MAGNESIUM ION | | Authors: | Pazy, Y, Silversmith, R.E, Guarinari, M, Zhao, R. | | Deposit date: | 2009-06-23 | | Release date: | 2010-02-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Identical phosphatase mechanisms achieved through distinct modes of binding phosphoprotein substrate.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3KYI
 | | Crystal structure of the phosphorylated P1 domain of CheA3 in complex with CheY6 from R. sphaeroides | | Descriptor: | CheY6 protein, Putative histidine protein kinase | | Authors: | Bell, C.H, Porter, S.L, Armitage, J.P, Stuart, D.I. | | Deposit date: | 2009-12-06 | | Release date: | 2010-02-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Using structural information to change the phosphotransfer specificity of a two-component chemotaxis signalling complex
Plos Biol., 8, 2010
|
|
6RH0
 | | Revisiting pH-gated conformational switch. Complex HK853-RR468 pH 5.5 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Response regulator, ... | | Authors: | Mideros-Mora, C, Casino, P, Marina, A. | | Deposit date: | 2019-04-18 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.87 Å) | | Cite: | Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases.
Nat Commun, 11, 2020
|
|
1SD5
 | | Crystal structure of Rv1626 | | Descriptor: | IODIDE ION, putative antiterminator | | Authors: | Morth, J.P, Feng, V, Perry, L.J, Svergun, D.I, Tucker, P.A, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2004-02-13 | | Release date: | 2004-09-21 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis.
Structure, 12, 2004
|
|
4LDZ
 | | Crystal structure of the full-length response regulator DesR in the active state | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | | Deposit date: | 2013-06-25 | | Release date: | 2014-07-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
MBio, 5, 2014
|
|
1RNL
 | | THE NITRATE/NITRITE RESPONSE REGULATOR PROTEIN NARL FROM NARL | | Descriptor: | GLYCEROL, NITRATE/NITRITE RESPONSE REGULATOR PROTEIN NARL, PLATINUM (II) ION | | Authors: | Baikalov, I, Schroder, I, Kaczor-Grzeskowiak, M, Grzeskowiak, K, Gunsalus, R.P, Dickerson, R.E. | | Deposit date: | 1996-04-17 | | Release date: | 1996-11-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the Escherichia coli response regulator NarL.
Biochemistry, 35, 1996
|
|
4L4U
 | | Crystal structure of construct containing A. aeolicus NtrC1 receiver, central and DNA binding domains | | Descriptor: | Transcriptional regulator (NtrC family) | | Authors: | Vidangos, N.K, Maris, A.E, Young, A, Hong, E, Pelton, J.G, Batchelor, J.D, Wemmer, D.E. | | Deposit date: | 2013-06-09 | | Release date: | 2013-08-28 | | Last modified: | 2013-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure, function, and tethering of DNA-binding domains in sigma (54) transcriptional activators.
Biopolymers, 99, 2013
|
|
1S8N
 | | Crystal structure of Rv1626 from Mycobacterium tuberculosis | | Descriptor: | AZIDE ION, putative antiterminator | | Authors: | Morth, J.P, Feng, V, Perry, L.J, Svergun, D.I, Tucker, P.A, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2004-02-03 | | Release date: | 2004-09-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.482 Å) | | Cite: | The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis.
Structure, 12, 2004
|
|
1U0S
 | | Chemotaxis kinase CheA P2 domain in complex with response regulator CheY from the thermophile thermotoga maritima | | Descriptor: | Chemotaxis protein cheA, Chemotaxis protein cheY | | Authors: | Park, S.Y, Beel, B.D, Simon, M.I, Bilwes, A.M, Crane, B.R. | | Deposit date: | 2004-07-14 | | Release date: | 2004-08-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | In different organisms, the mode of interaction between two signaling proteins is not necessarily conserved
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
6RH2
 | | Revisiting pH-gated conformational switch. Complex HK853-RR468 D53A pH 5.3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Response regulator, SULFATE ION, ... | | Authors: | Mideros-Mora, C, Casino, P, Marina, A. | | Deposit date: | 2019-04-18 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases.
Nat Commun, 11, 2020
|
|
6RH1
 | | Revisiting pH-gated conformational switch. Complex HK853-RR468 D53A pH 7 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Response regulator, SULFATE ION, ... | | Authors: | Mideros-Mora, C, Casino, P, Marina, A. | | Deposit date: | 2019-04-18 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases.
Nat Commun, 11, 2020
|
|
6RH7
 | | Revisiting pH-gated conformational switch. Complex HK853 mutant H260A -RR468 mutant D53A pH 7.5 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Response regulator, SULFATE ION, ... | | Authors: | Mideros-Mora, C, Casino, P, Marina, A. | | Deposit date: | 2019-04-18 | | Release date: | 2020-02-19 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Revisiting the pH-gated conformational switch on the activities of HisKA-family histidine kinases.
Nat Commun, 11, 2020
|
|
1W25
 | | Response regulator PleD in complex with c-diGMP | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, STALKED-CELL DIFFERENTIATION CONTROLLING PROTEIN, ... | | Authors: | Chan, C, Schirmer, T, Jenal, U. | | Deposit date: | 2004-06-28 | | Release date: | 2004-11-18 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Basis of Activity and Allosteric Control of Diguanylate Cyclase
Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
3A0R
 | | Crystal structure of histidine kinase ThkA (TM1359) in complex with response regulator protein TrrA (TM1360) | | Descriptor: | MERCURY (II) ION, Response regulator, Sensor protein | | Authors: | Yamada, S, Sugimoto, H, Kobayashi, M, Ohno, A, Nakamura, H, Shiro, Y. | | Deposit date: | 2009-03-24 | | Release date: | 2009-10-20 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structure of PAS-linked histidine kinase and the response regulator complex
Structure, 17, 2009
|
|
3BRE
 | | Crystal Structure of P.aeruginosa PA3702 | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Probable two-component response regulator | | Authors: | De, N, Pirruccello, M, Krasteva, P.V, Bae, N, Raghavan, R.V, Sondermann, H. | | Deposit date: | 2007-12-21 | | Release date: | 2008-04-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Phosphorylation-independent regulation of the diguanylate cyclase WspR.
Plos Biol., 6, 2008
|
|
3C3W
 | | Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR | | Descriptor: | SULFATE ION, TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR | | Authors: | Wisedchaisri, G, Wu, M, Sherman, D.R, Hol, W.G.J. | | Deposit date: | 2008-01-28 | | Release date: | 2008-04-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation
J.Mol.Biol., 378, 2008
|
|
4HYE
 | |
4IF4
 | |
4JAS
 | | Structural basis of a rationally rewired protein-protein interface (HK853mutant A268V, A271G, T275M, V294T and D297E and RR468mutant V13P, L14I, I17M and N21V) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Histidine kinase, MAGNESIUM ION, ... | | Authors: | Podgornaia, A.I, Casino, P, Marina, A, Laub, M.T. | | Deposit date: | 2013-02-19 | | Release date: | 2013-09-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling
Structure, 21, 2013
|
|
4JAV
 | | Structural basis of a rationally rewired protein-protein interface (HK853wt and RR468mutant V13P, L14I, I17M and N21V) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Histidine kinase, ... | | Authors: | Podgornaia, A.I, Casino, P, Marina, A, Laub, M.T. | | Deposit date: | 2013-02-19 | | Release date: | 2013-09-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling
Structure, 21, 2013
|
|
