4JAS

Structural basis of a rationally rewired protein-protein interface (HK853mutant A268V, A271G, T275M, V294T and D297E and RR468mutant V13P, L14I, I17M and N21V)

Summary for 4JAS

Entry DOI	10.2210/pdb4jas/pdb
Related	4JA2 4JAU 4JAV
Descriptor	Histidine kinase, Response regulator, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywords	bergerat fold, alpha/beta domain, signal transduction, autophosphorylation, phosphotransferase, dephosphorylation, histidine kinase, response regulator, phosphorylation, transferase-signaling protein complex, transferase/signaling protein
Biological source	Thermotoga maritima More
Total number of polymer chains	2
Total formula weight	43828.52
Authors	Podgornaia, A.I.,Casino, P.,Marina, A.,Laub, M.T. (deposition date: 2013-02-19, release date: 2013-09-04, Last modification date: 2023-11-08)
Primary citation	Podgornaia, A.I.,Casino, P.,Marina, A.,Laub, M.T. Structural basis of a rationally rewired protein-protein interface critical to bacterial signaling Structure, 21:1636-1647, 2013 Cited by PubMed: 23954504 DOI: 10.1016/j.str.2013.07.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation