4JAS
Structural basis of a rationally rewired protein-protein interface (HK853mutant A268V, A271G, T275M, V294T and D297E and RR468mutant V13P, L14I, I17M and N21V)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0000156 | molecular_function | phosphorelay response regulator activity |
| B | 0000160 | biological_process | phosphorelay signal transduction system |
| B | 0003677 | molecular_function | DNA binding |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP A 501 |
| Chain | Residue |
| A | ASN376 |
| A | TYR429 |
| A | ARG430 |
| A | VAL431 |
| A | SER434 |
| A | GLY441 |
| A | THR442 |
| A | GLY443 |
| A | GLY445 |
| A | LEU446 |
| A | MG502 |
| A | ASN380 |
| A | LYS383 |
| A | TYR384 |
| A | ASP411 |
| A | ILE414 |
| A | GLY415 |
| A | ILE416 |
| A | ILE424 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 502 |
| Chain | Residue |
| A | ASN376 |
| A | ASN380 |
| A | LYS383 |
| A | ADP501 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 201 |
| Chain | Residue |
| B | ASP10 |
| B | BFD53 |
| B | MET55 |
| B | HOH304 |
| B | HOH306 |
