2HKH
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![BU of 2hkh by Molmil](/molmil-images/mine/2hkh) | Crystal structure of the Fab M75 | Descriptor: | GLYCEROL, Immunoglobulin Heavy chain Fab fragment, Immunoglobulin Light chain Fab fragment | Authors: | Kral, V, Mader, P, Stouracova, R, Fabry, M, Sedlacek, J, Brynda, J. | Deposit date: | 2006-07-04 | Release date: | 2007-11-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Stabilization of antibody structure upon association to a human carbonic anhydrase IX epitope studied by X-ray crystallography, microcalorimetry, and molecular dynamics simulations. Proteins, 71, 2008
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2HKF
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![BU of 2hkf by Molmil](/molmil-images/mine/2hkf) | Crystal structure of the Complex Fab M75- Peptide | Descriptor: | Carbonic anhydrase 9, Immunoglobulin Heavy chain Fab fragment, Immunoglobulin Light chain Fab fragment | Authors: | Kral, V, Mader, P, Stouracova, R, Fabry, M, Horejsi, M, Brynda, J. | Deposit date: | 2006-07-04 | Release date: | 2007-11-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Stabilization of antibody structure upon association to a human carbonic anhydrase IX epitope studied by X-ray crystallography, microcalorimetry, and molecular dynamics simulations. Proteins, 71, 2008
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6MU3
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![BU of 6mu3 by Molmil](/molmil-images/mine/6mu3) | Anti-HIV-1 Fab 2G12 + Man7 re-refinement | Descriptor: | Fab 2G12, heavy chain, light chain, ... | Authors: | Wilson, I.A, Calarese, D.A, Stanfield, R.L. | Deposit date: | 2018-10-22 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.327 Å) | Cite: | Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc. Natl. Acad. Sci. U.S.A., 102, 2005
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6N41
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![BU of 6n41 by Molmil](/molmil-images/mine/6n41) | |
1YNT
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![BU of 1ynt by Molmil](/molmil-images/mine/1ynt) | Structure of the monomeric form of T. gondii SAG1 surface antigen bound to a human Fab | Descriptor: | 4F11E12 Fab variable heavy chain region, 4F11E12 Fab variable light chain region, CADMIUM ION, ... | Authors: | Graille, M, Stura, E.A, Bossus, M, Muller, B.H, Letourneur, O, Battail-Poirot, N, Sibai, G, Rolland, D, Le Du, M.H, Ducancel, F. | Deposit date: | 2005-01-25 | Release date: | 2005-12-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of the complex between the monomeric form of Toxoplasma gondii surface antigen 1 (SAG1) and a monoclonal antibody that mimics the human immune response J.Mol.Biol., 354, 2005
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1LO0
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![BU of 1lo0 by Molmil](/molmil-images/mine/1lo0) | Catalytic Retro-Diels-Alderase Transition State Analogue Complex | Descriptor: | 3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACID, If kappa light chain, Ig gamma 2a heavy chain | Authors: | Hugot, M, Reymond, J.L, Baumann, U. | Deposit date: | 2002-05-05 | Release date: | 2002-06-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue. Proc.Natl.Acad.Sci.USA, 99, 2002
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8G9X
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![BU of 8g9x by Molmil](/molmil-images/mine/8g9x) | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Changela, A, Gorman, J, Kwong, P.D. | Deposit date: | 2023-02-22 | Release date: | 2023-04-19 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (4.46 Å) | Cite: | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization. J.Virol., 97, 2023
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2A1W
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![BU of 2a1w by Molmil](/molmil-images/mine/2a1w) | Anti-cocaine antibody 7.5.21, crystal form I | Descriptor: | SULFATE ION, immunoglobulin heavy chain, immunoglobulin light chain kappa | Authors: | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | Deposit date: | 2005-06-21 | Release date: | 2005-06-28 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Flexibility Of Packing:
Four Crystal Forms Of An Anti-Cocaine Antibody 7.5.21 To be Published
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6ONA
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![BU of 6ona by Molmil](/molmil-images/mine/6ona) | |
2A77
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![BU of 2a77 by Molmil](/molmil-images/mine/2a77) | Anti-Cocaine Antibody 7.5.21, Crystal Form II | Descriptor: | GLYCEROL, Immunoglobulin Heavy Chain, Immunoglobulin Light Chain, ... | Authors: | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | Deposit date: | 2005-07-04 | Release date: | 2005-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Flexibility of Packing: Four Crystal Forms of an Anti-Cocaine Antibody 7.5.21 To be Published
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6UQR
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![BU of 6uqr by Molmil](/molmil-images/mine/6uqr) | Complex of IgE and Ligelizumab | Descriptor: | IgE, Ligelizumab, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Tarchevskaya, S.S, Kleinboelting, S, Jardetzky, T.S. | Deposit date: | 2019-10-21 | Release date: | 2019-12-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.6502912 Å) | Cite: | The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab. Nat Commun, 11, 2020
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1YEG
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![BU of 1yeg by Molmil](/molmil-images/mine/1yeg) | STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH REACTION PRODUCT | Descriptor: | ACETATE ION, IGG2A FAB FRAGMENT, PARANITROBENZYL ALCOHOL, ... | Authors: | Gigant, B, Knossow, M. | Deposit date: | 1997-05-29 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. Proc.Natl.Acad.Sci.USA, 94, 1997
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6OSR
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![BU of 6osr by Molmil](/molmil-images/mine/6osr) | |
4PTT
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![BU of 4ptt by Molmil](/molmil-images/mine/4ptt) | Crystal Structure of anti-23F strep Fab C05 | Descriptor: | ACETATE ION, Antibody pn132p2C05, heavy chain, ... | Authors: | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Smith, K, Schrader, J.W, Pai, E.F. | Deposit date: | 2014-03-11 | Release date: | 2015-03-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. J. Immunol., 196, 2016
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8G9W
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![BU of 8g9w by Molmil](/molmil-images/mine/8g9w) | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Changela, A, Gorman, J, Kwong, P.D. | Deposit date: | 2023-02-22 | Release date: | 2023-04-19 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (4.66 Å) | Cite: | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization. J.Virol., 97, 2023
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8G9Y
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![BU of 8g9y by Molmil](/molmil-images/mine/8g9y) | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Changela, A, Gorman, J, Kwong, P.D. | Deposit date: | 2023-02-22 | Release date: | 2023-04-19 | Last modified: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (4.28 Å) | Cite: | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization. J.Virol., 97, 2023
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5HDQ
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![BU of 5hdq by Molmil](/molmil-images/mine/5hdq) | MntC co-structure with mAB 305-78-7 | Descriptor: | ABC transporter substrate-binding protein, FE (III) ION, Fab Heavy Chain, ... | Authors: | Parris, K, Mosyak, L. | Deposit date: | 2016-01-05 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | High Resolution Mapping of Bactericidal Monoclonal Antibody Binding Epitopes on Staphylococcus aureus Antigen MntC. Plos Pathog., 12, 2016
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2BJM
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![BU of 2bjm by Molmil](/molmil-images/mine/2bjm) | SPE7:Anthrone Complex | Descriptor: | ANTHRONE, IGE SPE7 HEAVY CHAIN, IGE SPE7 LIGHT CHAIN | Authors: | James, L.C, Tawfik, D.S. | Deposit date: | 2005-02-04 | Release date: | 2005-08-18 | Last modified: | 2013-10-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure and Kinetics of a Transient Antibody Binding Intermediate Reveal a Kinetic Discrimination Mechanism in Antigen Recognition Proc.Natl.Acad.Sci.USA, 102, 2005
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2AI0
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![BU of 2ai0 by Molmil](/molmil-images/mine/2ai0) | Anti-Cocaine Antibody 7.5.21, Crystal Form III | Descriptor: | GLYCEROL, Immunoglobulin Heavy Chain, Immunoglobulin Light Chain kappa, ... | Authors: | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | Deposit date: | 2005-07-28 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Flexibility of Packing: Four Crystal Forms of an Anti-Cocaine Antibody 7.5.21 To be Published
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6MH2
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![BU of 6mh2 by Molmil](/molmil-images/mine/6mh2) | Structure of Herceptin Fab without antigen | Descriptor: | Herceptin Fab arm heavy chain, Herceptin Fab arm light chain | Authors: | Luthra, A, Langley, D.B, Christie, M, Christ, D. | Deposit date: | 2018-09-17 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Human Antibody Bispecifics through Phage Display Selection. Biochemistry, 58, 2019
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4DVA
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![BU of 4dva by Molmil](/molmil-images/mine/4dva) | The crystal structure of human urokinase-type plasminogen activator catalytic domain | Descriptor: | HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | Deposit date: | 2012-02-23 | Release date: | 2013-01-16 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody Biochem.J., 449, 2013
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1YEF
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![BU of 1yef by Molmil](/molmil-images/mine/1yef) | STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH SUBSTRATE ANALOGUE | Descriptor: | IGG2A FAB FRAGMENT, PARA-NITROBENZYL GLUTARYL GLYCINIC ACID, ZINC ION | Authors: | Gigant, B, Knossow, M. | Deposit date: | 1997-05-29 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release. Proc.Natl.Acad.Sci.USA, 94, 1997
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4PTU
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![BU of 4ptu by Molmil](/molmil-images/mine/4ptu) | Crystal Structure of anti-23F strep Fab C05 with rhamnose | Descriptor: | ACETATE ION, Antibody pn132p2C05, heavy chain, ... | Authors: | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Smith, K, Schrader, J.W, Pai, E.F. | Deposit date: | 2014-03-11 | Release date: | 2015-03-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.511 Å) | Cite: | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. J. Immunol., 196, 2016
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6VO3
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![BU of 6vo3 by Molmil](/molmil-images/mine/6vo3) | AMC009 SOSIP.v4.2 in complex with PGV04 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC009 SOSIP.v4.2 envelope glycoprotein gp120, ... | Authors: | Cottrell, C.A, de Val, N, Ward, A.B. | Deposit date: | 2020-01-29 | Release date: | 2020-09-23 | Last modified: | 2020-12-09 | Method: | ELECTRON MICROSCOPY (4.25 Å) | Cite: | Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers. J.Virol., 94, 2020
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12E8
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![BU of 12e8 by Molmil](/molmil-images/mine/12e8) | 2E8 FAB FRAGMENT | Descriptor: | IGG1-KAPPA 2E8 FAB (HEAVY CHAIN), IGG1-KAPPA 2E8 FAB (LIGHT CHAIN) | Authors: | Rupp, B, Trakhanov, S. | Deposit date: | 1998-03-14 | Release date: | 1998-08-05 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a monoclonal 2E8 Fab antibody fragment specific for the low-density lipoprotein-receptor binding region of apolipoprotein E refined at 1.9 A. Acta Crystallogr.,Sect.D, null, 1999
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