Crystal structure of the Fab M75

Summary for 2HKH

DescriptorImmunoglobulin Light chain Fab fragment, Immunoglobulin Heavy chain Fab fragment, GLYCEROL, ... (4 entities in total)
Functional Keywordsimmunoglobulin, fab fragment, immune system
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total molecular weight47640.03
Kral, V.,Mader, P.,Stouracova, R.,Fabry, M.,Sedlacek, J.,Brynda, J. (deposition date: 2006-07-04, release date: 2007-11-13, Last modification date: 2017-10-18)
Primary citation
Kral, V.,Mader, P.,Collard, R.,Fabry, M.,Horejsi, M.,Rezacova, P.,Kozisek, M.,Zavada, J.,Sedlacek, J.,Rulisek, L.,Brynda, J.
Stabilization of antibody structure upon association to a human carbonic anhydrase IX epitope studied by X-ray crystallography, microcalorimetry, and molecular dynamics simulations.
Proteins, 71:1275-1287, 2008
PubMed: 18041760 (PDB entries with the same primary citation)
DOI: 10.1002/prot.21821
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26314 1.2% 10.1% 5.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25