PDB: 5515 resultsInfo pagesStatus searchChemie searchBIRD

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5HRY	Computationally Designed Cyclic Dimer ank3C2_1 Descriptor: ank3C2_1 Authors: Cascio, D, McNamara, D.E, Fallas, J.A, Baker, D, Yeates, T.O. Deposit date: 2016-01-24 Release date: 2017-04-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
5J7D	Computationally Designed Thioredoxin dF106 Descriptor: COPPER (II) ION, Designed Thioredoxin dF106 Authors: Horowitz, S, Johansen, N, Olsen, J.G, Winther, J.R. Deposit date: 2016-04-06 Release date: 2016-10-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Computational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone Template. J.Mol.Biol., 428, 2016
6N4N	Crystal structure of the designed protein DNCR2/danoprevir/NS3a complex Descriptor: (2R,6S,12Z,13aS,14aR,16aS)-6-[(tert-butoxycarbonyl)amino]-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxo-1,2,3,5,6,7,8 ,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoro-2H-isoindole-2-carboxylate, NS3 protease, Rosetta-designed danoprevir/NS3a complex reader 2, ... Authors: Wang, Z, Foight, G.W, Baker, D, Maly, D.J. Deposit date: 2018-11-19 Release date: 2019-09-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Multi-input chemical control of protein dimerization for programming graded cellular responses. Nat.Biotechnol., 37, 2019
6MQU	PL5, synthetic transmembrane domain variant of human phospholamban Descriptor: PL5, designed TM pentamer Authors: Mravic, M, Thomaston, J.L, DeGrado, W.F. Deposit date: 2018-10-10 Release date: 2019-04-03 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.17 Å) Cite: Packing of apolar side chains enables accurate design of highly stable membrane proteins. Science, 363, 2019
6M9B	Wild-type streptavidin in complex with biotin solved by native SAD with data collected at 6 keV Descriptor: BIOTIN, Streptavidin Authors: Finke, A.D. Deposit date: 2018-08-23 Release date: 2019-04-17 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.548 Å) Cite: Making routine native SAD a reality: lessons from beamline X06DA at the Swiss Light Source. Acta Crystallogr D Struct Biol, 75, 2019
4HRL	Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2 Descriptor: Designed Ankyrin Repeat Protein 9_29, Receptor tyrosine-protein kinase erbB-2 Authors: Jost, C, Schilling, J, Plueckthun, A. Deposit date: 2012-10-28 Release date: 2013-10-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2. Structure, 21, 2013
4HRN	Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2 Descriptor: Designed Ankyrin Repeat Protein H10-2-G, Receptor tyrosine-protein kinase erbB-2 Authors: Jost, C, Schilling, J, Plueckthun, A. Deposit date: 2012-10-28 Release date: 2013-10-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2. Structure, 21, 2013
4HRM	Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2 Descriptor: Designed Ankyrin Repeat Protein 9_26, Domain I of receptor tyrosine-protein kinase erbB-2 Authors: Jost, C, Schilling, J, Plueckthun, A. Deposit date: 2012-10-28 Release date: 2013-10-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2. Structure, 21, 2013
1QYS	Crystal structure of Top7: A computationally designed protein with a novel fold Descriptor: TOP7 Authors: Kuhlman, B, Dantas, G, Ireton, G.C, Varani, G, Stoddard, B.L, Baker, D. Deposit date: 2003-09-11 Release date: 2003-11-25 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Design of a Novel Globular Protein Fold with Atomic-Level Accuracy Science, 302, 2003
1OPR	THE CRYSTAL STRUCTURE OF THE OROTATE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH OROTATE AND ALPHA-D-5-PHOSPHORIBOSYL-1-PYROPHOSPHATE Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, OROTATE PHOSPHORIBOSYLTRANSFERASE, ... Authors: Scapin, G, Sacchettini, J.C. Deposit date: 1995-01-06 Release date: 1996-01-06 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The crystal structure of the orotate phosphoribosyltransferase complexed with orotate and alpha-D-5-phosphoribosyl-1-pyrophosphate. Biochemistry, 34, 1995
7MLL	Solution structure of Exenatide (exendin-4) in 30-vol% trifluoroethanol using CS-Rosetta Descriptor: Exendin-4 Authors: Mishra, S.H, Bhavaraju, S. Deposit date: 2021-04-28 Release date: 2021-05-19 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Facilitated structure verification of the biopharmaceutical peptide exenatide by 2D heteronuclear NMR maps. J Pharm Biomed Anal, 203, 2021
7MP7	Rules for designing protein fold switches and their implications for the folding code Descriptor: Sb3 Authors: He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. Deposit date: 2021-05-04 Release date: 2022-05-18 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
7MN1	Rules for designing protein fold switches and their implications for the folding code Descriptor: Sa1 Authors: He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. Deposit date: 2021-04-30 Release date: 2022-05-18 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
7MQ4	Rules for designing protein fold switches and their implications for the folding code Descriptor: Sb1 Authors: He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. Deposit date: 2021-05-05 Release date: 2022-05-18 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
1RGR	Cyclic Peptides Targeting PDZ Domains of PSD-95: Structural Basis for Enhanced Affinity and Enzymatic Stability Descriptor: BETA-ALANINE, Presynaptic density protein 95, postsynaptic protein CRIPT peptide Authors: Piserchio, A, Salinas, G.D, Li, T, Marshall, J, Spaller, M.R, Mierke, D.F. Deposit date: 2003-11-12 Release date: 2004-05-18 Last modified: 2021-10-27 Method: SOLUTION NMR Cite: Targeting Specific PDZ Domains of PSD-95; Structural Basis for Enhanced Affinity and Enzymatic Stability of a Cyclic Peptide. Chem.Biol., 11, 2004
1RIM	E6-binding zinc finger (E6apc2) Descriptor: E6apc2 peptide Authors: Liu, Y, Liu, Z, Androphy, E, Chen, J, Baleja, J.D. Deposit date: 2003-11-17 Release date: 2004-08-03 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus. Biochemistry, 43, 2004
7NBI	Crystal structure of a monomeric FLT3 Ligand variant Descriptor: Fms-related tyrosine kinase 3 ligand, SULFATE ION Authors: Pannecoucke, E, Raes, L, Savvides, S.N. Deposit date: 2021-01-26 Release date: 2021-04-28 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Engineering and crystal structure of a monomeric FLT3 ligand variant. Acta Crystallogr.,Sect.F, 77, 2021
1R9V	NMR Structure of a D,L-Alternating Dodecamer of Norleucine Descriptor: BOC-(D-NLE-L-NLE)4-D-NLE(METHYL)-L-NLE-D-NLE-L-NLE METHYL ESTER Authors: Navarro, E, Celda, B. Deposit date: 2003-10-31 Release date: 2003-12-02 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Solution NMR Structure of a D,L-Alternating Oligonorleucine as a Model of Beta-Helix Biopolymers, 59, 2001
7MN2	Rules for designing protein fold switches and their implications for the folding code Descriptor: Sb2 Authors: He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. Deposit date: 2021-04-30 Release date: 2022-05-18 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
1RIJ	E6-bind Trp-cage (E6apn1) Descriptor: E6apn1 peptide Authors: Liu, Y, Liu, Z, Androphy, E, Chen, J, Baleja, J.D. Deposit date: 2003-11-17 Release date: 2004-08-03 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus. Biochemistry, 43, 2004
7NLV	WILDTYPE CORE-STREPTAVIDIN WITH a conjugated BIOTINYLATED PYRROLIDINE II Descriptor: 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-((S)-pyrrolidin-3-yl)pentanamide, Streptavidin Authors: Nodling, A.R, Santi, N, Tsai, Y.H, Rizkallah, P, Luk, L.Y.P, Jin, Y. Deposit date: 2021-02-22 Release date: 2022-03-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.29 Å) Cite: The role of streptavidin and its variants in catalysis by biotinylated secondary amines. Org.Biomol.Chem., 19, 2021
6VEH	Computationally designed C3-symmetric homotrimer from HEAT repeat protein Descriptor: HEAT repeat domain-containing protein Authors: Bick, M.J, Ueda, G, Baker, D. Deposit date: 2020-01-02 Release date: 2020-08-05 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.303 Å) Cite: Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens. Elife, 9, 2020
7LIB	X-ray crystal structure of a cyclic peptide containing beta-2-microglobulin (63-69) and a gamma-methylornithine turn unit Descriptor: Cyclic peptide ORD-TYR-LEU-LEU-PHI-TYR-THR-GLU-GMO-LYS-VAL-THR-MVA-THR-VAL-LYS Authors: Wierzbicki, M, Nowick, J.S, Li, X. Deposit date: 2021-01-26 Release date: 2021-08-11 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.1 Å) Cite: An Improved Turn Structure for Inducing beta-Hairpin Formation in Peptides. Angew.Chem.Int.Ed.Engl., 60, 2021
7LL7	[2]Catenane From MccJ25 Variant G12C G21C Descriptor: GLY-GLY-ALA-GLY-HIS-VAL-PRO-GLU-TYR-PHE, VAL-CYS-ILE-GLY-THR-PRO-ILE-SER-PHE-TYR-CYS Authors: Link, A.J, Schroeder, H.V. Deposit date: 2021-02-03 Release date: 2021-08-04 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Dynamic covalent self-assembly of mechanically interlocked molecules solely made from peptides. Nat.Chem., 13, 2021
6V8E	Computationally designed C3-symmetric homotrimer from TPR repeat protein Descriptor: Designed protein Authors: Sankaran, B, Ueda, G, Zwart, P.H, Baker, D. Deposit date: 2019-12-10 Release date: 2020-08-12 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens. Elife, 9, 2020

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