1RGR
Cyclic Peptides Targeting PDZ Domains of PSD-95: Structural Basis for Enhanced Affinity and Enzymatic Stability
Summary for 1RGR
Entry DOI | 10.2210/pdb1rgr/pdb |
Descriptor | Presynaptic density protein 95, postsynaptic protein CRIPT peptide, BETA-ALANINE (3 entities in total) |
Functional Keywords | pdz1 domain, structural protein-de novo protein complex, structural protein/de novo protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane; Peripheral membrane protein: P31016 |
Total number of polymer chains | 2 |
Total formula weight | 11718.13 |
Authors | Piserchio, A.,Salinas, G.D.,Li, T.,Marshall, J.,Spaller, M.R.,Mierke, D.F. (deposition date: 2003-11-12, release date: 2004-05-18, Last modification date: 2021-10-27) |
Primary citation | Piserchio, A.,Salinas, G.D.,Li, T.,Marshall, J.,Spaller, M.R.,Mierke, D.F. Targeting Specific PDZ Domains of PSD-95; Structural Basis for Enhanced Affinity and Enzymatic Stability of a Cyclic Peptide. Chem.Biol., 11:469-473, 2004 Cited by PubMed: 15123241DOI: 10.1016/j.chembiol.2004.03.013 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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